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【Animal Modeling】-Establishment of a Rat Model of Hyperuricemia and Its Complications

【Animal Modeling】-Establishment of a Rat Model of Hyperuricemia and Its Complications

To establish a stable and efficient rat model of hyperuricemia complicated with liver and kidney injury and gouty arthritis...

2022-08-23
【Animal modeling】-Evaluation of the curative effect of Fenbid on the model of lumbar disc herniation in rats

【Animal modeling】-Evaluation of the curative effect of Fenbid on the model of lumbar disc herniation in rats

To study the effect of cyclooxygenase inhibitor Fenbid on lumbar disc herniation...

2022-08-23
【Animal Modeling】-Comparative Study of Graves Disease Animal Models in Mice and Macaques

【Animal Modeling】-Comparative Study of Graves Disease Animal Models in Mice and Macaques

This study aims to start from the immune-related mechanism of Graves\' disease, compare the mouse and macaque GD animal models in our previous studies, and explore the differences in the characteristics of different animal GD models, and based on the...

2022-08-23
【Animal Modeling】-Carbon tetrachloride induced inbred C57BL/6 mice to establish liver fibrosis model

【Animal Modeling】-Carbon tetrachloride induced inbred C57BL/6 mice to establish liver fibrosis model

To compare the effects of different doses of carbon tetrachloride in inducing hepatic fibrosis in inbred C57BL/6 mice, so as to establish a stable hepatic fibrosis model...

2022-08-23
【Animal Modeling】-Characteristics of cardiac structure and function pathological process in a mouse model of pressure overload heart failure

【Animal Modeling】-Characteristics of cardiac structure and function pathological process in a mouse model of pressure overload heart failure

To establish a mouse model of heart failure, and to comprehensively evaluate the characteristic changes of cardiac function and structure during the development of the disease by using ultrasound imaging and pathological techniques...

2022-08-23
【Animal modeling】-Lipopolysaccharide-induced knee joint fibroblast-like synovial cell inflammation model in SD rats and analysis of its characteristics

【Animal modeling】-Lipopolysaccharide-induced knee joint fibroblast-like synovial cell inflammation model in SD rats and analysis of its characteristics

To establish a primary culture method of normal knee synovial cells in (SD) rats and a lipopolysaccharide-induced fibroblast-like synovial cell inflammation model...

2022-08-23
【Animal modeling】-Establishment and applicability evaluation of animal model of pelvic organ prolapse

【Animal modeling】-Establishment and applicability evaluation of animal model of pelvic organ prolapse

To establish a rat animal model that can reflect the similar pathological changes of the sacral ligament in patients with pelvic organ prolapse, to explore the effects of increasing the intensity of birth trauma and simulating menopause on the histop...

2022-08-23
【Animal modeling】-Experimental study on the preparation of SD rat portal hypertension animal model by ligation of left branch

【Animal modeling】-Experimental study on the preparation of SD rat portal hypertension animal model by ligation of left branch

To explore whether simple left portal vein ligation can form stable portal hypertension and whether nitric oxide plays a corresponding role in it...

2022-08-23
【Animal Modeling】-Study on the establishment of a rat model of coronary heart disease combined with Qi deficiency and blood stasis syndrome

【Animal Modeling】-Study on the establishment of a rat model of coronary heart disease combined with Qi deficiency and blood stasis syndrome

To explore the establishment of the rat model of CHD combined with qi deficiency and blood stasis syndrome by analyzing the tongue manifestations of the rat model of coronary heart disease with qi deficiency and blood stasis syndrome combined with pa...

2022-08-23
【Animal Modeling】- Establishment of a mouse model of lung metastasis and postoperative recurrence after bone marrow injection

【Animal Modeling】- Establishment of a mouse model of lung metastasis and postoperative recurrence after bone marrow injection

To establish a model of lung metastasis and postoperative recurrence by bone marrow injection, to reveal the superiority and feasibility of the model by bone marrow injection, and to provide a new research basis for the study of lung metastasis of ma...

2022-08-23
【Animal Modeling】-Making a Rabbit Myocardial Infarction Model with Minimally Invasive Cardiac Catheterization

【Animal Modeling】-Making a Rabbit Myocardial Infarction Model with Minimally Invasive Cardiac Catheterization

To investigate the myocardial infarction (MI) model in rabbits created by occlusion of coronary artery by cardiac catheterization...

2022-08-23
【Animal Modeling】-High-fat diet-induced non-alcoholic fatty liver disease cynomolgus monkey model

【Animal Modeling】-High-fat diet-induced non-alcoholic fatty liver disease cynomolgus monkey model

To establish an animal model of high-fat diet-induced non-alcoholic fatty liver disease in cynomolgus monkeys, to analyze the effect of high-fat diet feeding time on the formation of NAFLD in animals, and to explore the relationship between high-fat ...

2022-08-23
【Animal Modeling】-Usage-guided injection of human lung cancer cells into the left ventricle to establish a mouse model of bone metastasis

【Animal Modeling】-Usage-guided injection of human lung cancer cells into the left ventricle to establish a mouse model of bone metastasis

To establish a mouse model of bone metastasis by intracardiac injection of human lung cancer cells by ultrasound guidance...

2022-08-23
【Animal modeling】-Construction of inhibin gene knockout mouse model and preliminary analysis of phenotype

【Animal modeling】-Construction of inhibin gene knockout mouse model and preliminary analysis of phenotype

To construct an inhibin knockout mouse model by gene editing technology of clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated protein 9 (Cas9) and preliminary analysis of its phenotype...

2022-08-23
【Animal Modeling】-Experimental Study on Establishing Rat Obesity Model with High Calorie Feed

【Animal Modeling】-Experimental Study on Establishing Rat Obesity Model with High Calorie Feed

To observe the effect of using high-calorie diet to establish an obesity model in rats, as well as the modeling differences between the two breeds of rats, and to compare different methods of evaluating obesity and screening methods of obesity-sensit...

2022-08-23
【Animal modeling】-Establishment of a mouse model of salt-sensitive hypertension

【Animal modeling】-Establishment of a mouse model of salt-sensitive hypertension

To establish a mouse model of salt-sensitive hypertension, and use the antihypertensive drug nifedipine to verify the validity of the model....

2022-08-23