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【Animal Modeling】-Establishment and evaluation of a rat model of mixed bacterial pneumonia

【Animal Modeling】-Establishment and evaluation of a rat model of mixed bacterial pneumonia

To establish a mixed bacterial infection pneumonia model of Staphylococcus aureus, Streptococcus pneumoniae and Escherichia coli, and provide animal model support for drug efficacy evaluation...

2022-08-05
【Animal Modeling】-Comparison of pathological damage and intestinal flora of two UC mouse models

【Animal Modeling】-Comparison of pathological damage and intestinal flora of two UC mouse models

To establish a mouse model of ulcerative colitis with dextran sodium sulfate (DSS) and 2,4,6-trinitrobenzenesulfonic acid (TNBS), and to compare the clinical symptoms, pathological damage of colon and colonic flora...

2022-08-05
【Animal Modeling】-Establishment and evaluation of a mouse model of human coronavirus 229E cold-damp epidemic virus attacking the lung syndrome and disease-syndrome combination

【Animal Modeling】-Establishment and evaluation of a mouse model of human coronavirus 229E cold-damp epidemic virus attacking the lung syndrome and disease-syndrome combination

To establish a mouse model of human coronavirus 229E cold-damp epidemic virus attacking the lung syndrome combined with disease and syndrome, to observe the consistency of TCM syndromes, disease manifestations and typical clinical manifestations of v...

2022-08-05
【Animal Modeling】-Comparative study of photochemical method and suture method to make focal cerebral infarction rat model

【Animal Modeling】-Comparative study of photochemical method and suture method to make focal cerebral infarction rat model

To investigate the photochemical method and suture method for two different animal models of focal cerebral infarction, and to analyze the correlation between the infarct volume and behavior of experimental animals caused by different modeling method...

2022-08-05
【Animal Modeling】-Construction of a comparative transcriptomic database of animal models of coronavirus infection

【Animal Modeling】-Construction of a comparative transcriptomic database of animal models of coronavirus infection

To construct a comparative transcriptomic database of animal models of coronavirus infection, compare the similarities and differences between human and animal models of coronavirus infection from the level of gene expression, and provide data suppor...

2022-08-05
【Animal modeling】-Study on establishment of rat model of uric acid nephropathy

【Animal modeling】-Study on establishment of rat model of uric acid nephropathy

To establish a reasonable and stable rat model of uric acid nephropathy, and to provide a pathological model for screening and research on the treatment of uric acid nephropathy...

2022-08-05
【Animal modeling】-Comparative study on the establishment of rabbit knee osteoarthritis model by modified Hulth method and type Ⅱ collagenase injection method

【Animal modeling】-Comparative study on the establishment of rabbit knee osteoarthritis model by modified Hulth method and type Ⅱ collagenase injection method

To compare and analyze the differences between two common modeling methods for rabbit knee osteoarthritis models, and to provide reference for the selection of different types of knee osteoarthritis animal models...

2022-08-05
【Animal modeling】-Preliminary study on the myocardial injury model of rhesus monkeys induced by isoproterenol

【Animal modeling】-Preliminary study on the myocardial injury model of rhesus monkeys induced by isoproterenol

To explore the method of using isoproterenol to induce myocardial injury in rhesus monkeys...

2022-08-05
【Animal modeling】-Expression and significance of HIF-1α, RhoA and SOX9 in adenine-induced chronic kidney disease rat model

【Animal modeling】-Expression and significance of HIF-1α, RhoA and SOX9 in adenine-induced chronic kidney disease rat model

To observe the expression of HIF-1α, RhoA and SOX9 in adenine-induced chronic kidney disease model in rats and their relationship with renal interstitial fibrosis...

2022-08-05
【Animal modeling】-Methods and comparison of orthotopic mouse pancreatic cancer model suitable for minimally invasive ablation research

【Animal modeling】-Methods and comparison of orthotopic mouse pancreatic cancer model suitable for minimally invasive ablation research

To explore the advantages and disadvantages of using tumor cell orthotopic injection and tumor tissue block transplantation to establish a mouse pancreatic cancer orthotopic model, and to provide technical reference for the establishment of a mouse p...

2022-08-05
【Animal modeling】-Construction and evaluation of doxorubicin-induced chronic cardiotoxicity model in mice

【Animal modeling】-Construction and evaluation of doxorubicin-induced chronic cardiotoxicity model in mice

To evaluate the modeling effect of different concentrations of doxorubicin-induced cardiotoxicity model in mice based on pathological changes...

2022-08-05
【Animal Modeling】- Overexpression of LAMP2A in the substantia nigra improves motor function in a rhesus monkey model of Parkinson\'s disease

【Animal Modeling】- Overexpression of LAMP2A in the substantia nigra improves motor function in a rhesus monkey model of Parkinson's disease

To observe the effect of overexpression of lysosome-associated membrane protein 2A in substantia nigra on chaperone-mediated autophagy on motor behavior in a rhesus monkey model of Parkinson\'s disease...

2022-08-04
【Animal Modeling】-Construction and Evaluation of Humanized Mouse Model of Pancreatic Cancer Immune System

【Animal Modeling】-Construction and Evaluation of Humanized Mouse Model of Pancreatic Cancer Immune System

To construct and evaluate a humanized mouse model of pancreatic cancer immune system, in order to provide an ideal preclinical model for the immunotherapy of pancreatic cancer...

2022-08-04
【Animal Modeling】-3D Reconstruction and Vascular 3D Printing Model of Miniature Pig Lungs

【Animal Modeling】-3D Reconstruction and Vascular 3D Printing Model of Miniature Pig Lungs

To discuss the establishment of 3D reconstruction model of minipig lungs and the application of 3D printing model...

2022-08-04
【Animal modeling】-Arachidonic acid-induced establishment of diffuse cerebral thrombosis model in rats

【Animal modeling】-Arachidonic acid-induced establishment of diffuse cerebral thrombosis model in rats

Objective To establish and optimize the rat model of diffuse cerebral thrombosis induced by arachidonic acid...

2022-08-04
【Animal Modeling】-Preparation of a mouse model of diarrhea-type irritable bowel syndrome induced by acetic acid combined with restraint stress

【Animal Modeling】-Preparation of a mouse model of diarrhea-type irritable bowel syndrome induced by acetic acid combined with restraint stress

A mouse model of diarrhea-predominant irritable bowel syndrome was established by rectal infusion of 3% acetic acid (AA) combined with restraint stress, and the feasibility of the model was evaluated...

2022-08-04