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What is the mechanism of Peli1\'s regulation of microglia phagocytosis and Alzheimer\'s pathology?

What is the mechanism of Peli1's regulation of microglia phagocytosis and Alzheimer's pathology?

E3 ubiquitin ligase (ie Peli1) directly mediates C/EBPβ ubiquitination modification and induces its degradation, a new mechanism that affects the phagocytic function of amyloid β (Amyloid-β, Aβ) by microglia. The pathological mechanism and clinical t...

2020-10-23
Type 1 diabetes may start in the womb as early as possible?

Type 1 diabetes may start in the womb as early as possible?

Diabetes diagnosed within 6 months of age is usually considered to be caused by a single gene mutation, not type 1 diabetes...

2020-10-23
Respiratory syncytial virus (RSV) vaccine quickly induces strong immunity!

Respiratory syncytial virus (RSV) vaccine quickly induces strong immunity!

GlaxoSmithKline (GSK) recently announced that its respiratory syncytial virus (RSV) candidate vaccine is well tolerated and immune to maternal immunity (GSK3888550A vaccine) and elderly immunity (GSK3844766A vaccine) in Phase I/II studies. Strong ori...

2020-10-23
The new generation of PI3Kδ inhibitor/new CD20 monoclonal antibody combination is more effective in the treatment of leukemia

The new generation of PI3Kδ inhibitor/new CD20 monoclonal antibody combination is more effective in the treatment of leukemia

The U.S. Food and Drug Administration (FDA) granted Fast Track Qualification (FTD) for the combined use of ubrituximab and umbralisib (U2) to treat adult chronic lymphocytic leukemia (CLL)...

2020-10-23
Key brain mutations affect obesity

Key brain mutations affect obesity

Scientists at the University of Copenhagen have found that obesity is a brain-related disease. Specifically, because genetic mutations affect the way the brain processes sensory information and regulates diet and behavior, some people are at increase...

2020-10-23
What are the risks of breast cancer drugs?

What are the risks of breast cancer drugs?

New research led by Flinders University has found a link between beta-blockers and the survival outcomes of certain breast cancer patients...

2020-10-23
Research reveals the vulnerability of cancer cells

Research reveals the vulnerability of cancer cells

One of the biggest challenges in developing cancer drugs is the diversity of cancer types. Cancers originate from a variety of cells and tissues. Each cancer has its own characteristics, performance and sensitivity to anticancer drugs....

2020-10-23
COVID-19 rapid test shows high sensitivity

COVID-19 rapid test shows high sensitivity

Researchers from the University of Sheffield recently published their evaluation results of a new, rapid COVID-19 testing technology...

2020-10-23
Spinal cord stem cells can help repair after injury

Spinal cord stem cells can help repair after injury

Spinal cord injury usually leads to permanent dysfunction. A new study published in the \\\"Science\\\" magazine of the Karolinska Institute in Sweden shows that it can stimulate mouse spinal cord stem cells to form a large number of new ol...

2020-10-23
Oral microorganisms cause cancer

Oral microorganisms cause cancer

A study by Yvonne Kapila of the University of California, San Francisco and others published in the journal PLOS Pathogen on October 1 showed that pathogens found in the tissues around the teeth can lead to the occurrence of highly aggressive oral ca...

2020-10-23
DNA mutations cause bladder cancer

DNA mutations cause bladder cancer

In a recent study, the first comprehensive study of DNA mutations in bladder tissues in healthy and bladder cancer patients showed that \"cancer-driven\" mutations are common in healthy bladder tissues...

2020-10-23
Nitric oxide can be used to treat COVID-19

Nitric oxide can be used to treat COVID-19

Researchers at Uppsala University found that the effective treatment of the coronavirus behind the 2003 SARS epidemic also applies to the closely related SARS-CoV-2...

2020-10-23
Targeted DNA damage repair can help treat cancer

Targeted DNA damage repair can help treat cancer

Due to the lack of good targets and the genetic variation characteristics of tumors, platinum-based chemotherapy is still the main treatment for many cancers...

2020-10-23
Individualized cancer therapy can effectively improve patient outcomes

Individualized cancer therapy can effectively improve patient outcomes

Researchers from the University of California, San Diego School of Medicine reported that for patients receiving advanced cancer treatment at the Moores Cancer Center of UC San Diego Health, if they receive personalized cancer treatment, they are mor...

2020-10-23
Miniature brain \"tweezers\" help treat Parkinson\'s disease

Miniature brain "tweezers" help treat Parkinson's disease

A collaborative study led by Dr. Nora Bengoa-Vergniory of the Oxford Parkinson’s Disease Center suggests that compounds called “molecular tweezers” may become promising disease-modifying treatments for Parkinson’s disease...

2020-10-23
Genetic barcode reveals evolutionary route of new coronavirus

Genetic barcode reveals evolutionary route of new coronavirus

In a recent study, researchers from Drexel University reported a method that can quickly identify and flag mutations of the COVID-19 virus...

2020-10-23