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In the 17th century, mice began to be used in animal modeling. Today, the mouse has become the most widely used and detailed experimental animal. However, since mice have no sweat glands and prefer to live in a dark environment that is less adapted t...
2020-07-22At the end of the 19th century, the application of animal-derived serum to treat infections in animal experiments was the first attempt to develop antibody drugs. The successful establishment of hybridoma technology in 1975 greatly promoted the devel...
2020-07-22How many years has your pet dog been with you? According to the famous \"dog\'s age rule\", a dog\'s year is equal to a person\'s seven years. A study published in \"Cell Systems\" (CellPress Cell Press) on July 2 shows that this ...
2020-07-22
Many friends who cooperate with Zhonghong Boyuan in animal modeling will ask, how do you prepare reagents when modeling?...
2020-07-21In animal experiments, it may be necessary to anesthetize animals, but most of the references to anesthetics in the data are limited to effects, route of administration, side effects, etc. In addition to certain drugs for injection (such as barbitura...
2020-07-21...
2020-07-21Esophageal cancer is mainly divided into squamous cell carcinoma (SCC) and adenocarcinoma (EAC) in histology, and more than 90% are SCC. The animal models of esophageal cancer mainly include esophageal squamous cell carcinoma animal models and esoph...
2020-07-21Perioperative neurocognitive disorder (PND) refers to the changes in mental activity, personality, social ability, and cognitive ability of patients after anesthesia and surgery. It is common in elderly patients. Clarifying its pathophysiological mec...
2020-07-20How to choose animal experiment base? As a researcher in pathological biology in Nanchang, animal experiments are indispensable, but the experiments have very strict requirements on resources and venues. Therefore, it is difficult for general schools...
2020-07-17将对数生长的肿瘤细胞收集 ， 用无血清基质 10.0ml， 于 1500 转/ 分， 离心3min， 连续洗 3 次， 最后用无血清基质混匀， 用血球计数器计算肿瘤细胞数量( 平均 5 个中方格的细胞计数×104即是肿瘤数/ 毫升) 。...
2020-07-17Since Bernard injected bile and olive oil in 1856 and made the first acute pancreatitis animal model in canine pancreas control, after more than a century of development, scholars from various countries have designed many animal models of AP and cond...
2020-07-17To simulate human PD, the ideal animal model should have the following characteristics: (1) The number and morphology of dopaminergic neurons at birth are normal, and gradually decrease gradually during youth, the reduction is more than 50%, and it i...
2020-07-17Adeno-associated viruses belong to the Parvovirus family, which are non-enveloped single-stranded linear DNA viruses with a genome size of approximately 4.7 kb. Using adeno-associated viruses can transfer foreign genes into animal tissues and cells. ...
2020-07-17Medical device safety and effectiveness evaluation research should use scientific and reasonable evaluation methods, of which animal experiment is one of the important means, which is an important research in product design and development, and can p...
2020-07-17Some research institutes clearly require that animal experiment results must be reproducible before they enter the clinic. But NIH said there is no plan for all institutes to implement such standards. In 2014, NIH began requiring researchers to inclu...
2020-07-17The benefits of experiment outsourcing are obvious, but it is precisely because many people ran for these intuitive benefits that they didn’t know anything or consulted this information before outsourcing, so they fell behind and should pay attention...
2020-07-17