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Objective To evaluate the effects of ethanol, isopropanol, acetone and dimethyl sulfoxide on zebrafish embryonic development, especially eye development, and to provide references for its application in the study of zebrafish eye disease models....
2020-07-24
Pigs are considered to be an important host or \"mixing container\" for the production of pandemic influenza viruses. Systematic surveillance of swine flu viruses is essential for early warning and prevention of the next pandemic....
2020-07-24Objective: To establish acute and chronic hyperuricemia models in rats, use positive drugs to verify the sclerosis of the two models, and provide model tools for the development of anti-hyperuric acid drugs....
2020-07-23Simulating human aging: Ideally, all biomedical research related to humans should be conducted in humans, but due to many ethical and technical considerations, this is obviously unrealistic. Therefore, it is necessary to model human aging in non-huma...
2020-07-23
\\\"Demyelination diseases, such as multiple sclerosis and leukocyte dystrophy, are characterized by the destruction of the protective myelin sheath surrounding axons. This demyelination phenomenon may be due to autoimmune reactions or the myeli...
2020-07-23In the field of medical and biological research, especially in the safety assessment of tumors, immunity, drugs, biologics, and preclinical screening of effective drugs, NudeMouse (\"naked mice\") has always been an indispensable experiment...
2020-07-23Spinal cord injury (SCI) is caused by the displacement of herniated bone fragments in the vertebral body or spinal canal, causing varying degrees of damage to the spinal cord or cauda equina, as well as changes in motor, sensory and sphincter functio...
2020-07-23
Reviewing the data collected from the review and the summary of Table 11 at the end of the review, we can see that the choice of the appropriate system is different, as long as the metabolism of the compound under consideration involves different enz...
2020-07-23
Zika virus (ZIKV) infection is a major public health problem in the world. The World Health Organization has declared Zika virus a “public health emergency of international concern”. In 2015, Zika disease broke out in Brazil, where a large number of ...
2020-07-23Although the national epidemic gradually disappeared, the epidemic in Beijing \"rebounded\" and affected the hearts of people across the country. During active screening, several asymptomatic carriers were found. This must have taught us al...
2020-07-23Recently, in the fight against the global pandemic, exciting innovations have inspired the world, and the world has successfully established a new coronavirus animal model! The mission of the Institute of Animal Science of the Chinese Academy of Medi...
2020-07-23Non-alcoholic fatty liver disease (NAFLD) is a liver syndrome without alcohol abuse, including simple fatty liver, steatohepatitis, fatty liver fibrosis and cirrhosis. It can range from simple fatty liver to non-alcoholic steatohepatitis (NASH) to li...
2020-07-23
Human viral diseases include Creutzfeldt-Jakob disease (CJD) and Gerstmann syndrome (GSS). Scientists from University College London and other institutions recently published a research report in the international journal PLoSBiology, which is based ...
2020-07-23Retinal vascular diseases, such as exudative age-related macular degeneration (eAMD), diabetic macular edema (DME), and proliferative diabetic retinopathy (PDR), all cause persistent and progressive vascular leakage. The disease indicates leakage and...
2020-07-23
Atherosclerosis is the most common underlying cause of cardiovascular disease in many people, and the main cause of morbidity and mortality. Atherosclerosis is a chronic inflammatory process involving multiple cell types and cytokines. Its developmen...
2020-07-22Biomedicine has always been a world dominated by men, which is not only reflected in the vast majority of researchers engaged in biomedical research, but also in the laboratory animals they use. This number far exceeds that of women....
2020-07-22