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【Animal modeling】-Propofol protects against cerebral ischemia-reperfusion injury and may be related to the inhibition of gap junction function

【Animal modeling】-Propofol protects against cerebral ischemia-reperfusion injury and may be related to the inhibition of gap junction function

To investigate the relationship between the protective effect of propofol on cerebral ischemia-reperfusion injury and gap junctions and its possible mechanism...

2022-07-04
What is an animal with NK cell immune deficiency? -【Animal Modeling】

What is an animal with NK cell immune deficiency? -【Animal Modeling】

Beige mice are mutant mice with immunodeficiency in NK cells, and bg is a recessive mutant gene on chromosome 13...

2022-07-04
【Animal Modeling】-Effect of ovariectomy on skin aging in osteoporotic rats

【Animal Modeling】-Effect of ovariectomy on skin aging in osteoporotic rats

The osteoporosis model constructed by ovariectomized rats is the most suitable model for the study of postmenopausal osteoporosis. However, there is little research on the effect of ovariectomized rats on the skin. The purpose of this study was to ob...

2022-07-04
【Animal modeling】-Effect of p53 knockout on neurobehavior and the number of neurons in barrel cortex in mice

【Animal modeling】-Effect of p53 knockout on neurobehavior and the number of neurons in barrel cortex in mice

To explore the role of p53 gene in neurobehavioral activity in mice and its effect on the number of neurons in barrel cortex...

2022-07-04
【Animal modeling】-Biological characteristics of type 2 diabetes db/db mice

【Animal modeling】-Biological characteristics of type 2 diabetes db/db mice

To observe the biological characteristics of db/db mice, and to provide the basis for the experimental research and application of this strain of animals...

2022-07-04
【Animal modeling】-Effect of thalidomide on bisphosphonate-related osteonecrosis of the jaw

【Animal modeling】-Effect of thalidomide on bisphosphonate-related osteonecrosis of the jaw

To study the effect of thalidomide on bisphosphonate-related osteonecrosis of the jaw...

2022-07-04
【Animal modeling】-Effect of repeated propofol anesthesia on spatial memory and long-term enhancement in young rats under hypoxia

【Animal modeling】-Effect of repeated propofol anesthesia on spatial memory and long-term enhancement in young rats under hypoxia

Propofol is the most commonly used intravenous anesthesia for induction and maintenance anesthesia...

2022-07-04
【Animal Modeling】-Ultrasonic radiation force combined with targeted ultrasound microbubbles to evaluate renal ischemia-reperfusion injury in mice

【Animal Modeling】-Ultrasonic radiation force combined with targeted ultrasound microbubbles to evaluate renal ischemia-reperfusion injury in mice

To investigate the sensitivity and feasibility of ultrasonic radiation force to promote the adhesion of targeted microbubbles to improve the detection of renal ischemia-reperfusion (IR) injury...

2022-07-04
【Animal modeling】-Study on the protective effect of salvianolic acid A on the kidney of ZDF rats and the inhibition of lipoprotein-associated phospholipase A2

【Animal modeling】-Study on the protective effect of salvianolic acid A on the kidney of ZDF rats and the inhibition of lipoprotein-associated phospholipase A2

To observe the protective effect of salvianolic acid A on Zucker diabetic obese rats (nephropathy) and the effect on the expression of lipoprotein-related phospholipase A2...

2022-07-02
【Animal Modeling】-Comparison of the effect of gene therapy and traditional non-surgical therapy on postpartum stress urinary incontinence model rats

【Animal Modeling】-Comparison of the effect of gene therapy and traditional non-surgical therapy on postpartum stress urinary incontinence model rats

To study the effect of TGF-β1 gene therapy on rat model of postpartum stress urinary incontinence, and to explore the ideal new non-surgical treatment method for the disease...

2022-07-02
【Animal modeling】-M4 receptor blocker MT3 inhibits form deprivation myopia in guinea pigs

【Animal modeling】-M4 receptor blocker MT3 inhibits form deprivation myopia in guinea pigs

To investigate the inhibitory effect of the highly selective M4 receptor blocker MT3 on form deprivation myopia in guinea pigs and its potential mechanism...

2022-07-02
【Animal Modeling】-Intervention of Fufang Dihuang Granules on Microglia Activation and Neurobehavior in Parkinson\\

【Animal Modeling】-Intervention of Fufang Dihuang Granules on Microglia Activation and Neurobehavior in Parkinson

To investigate the intervention effect of Fufang Dihuang Granules on the activation of nigrostriatal microglia, the expression of inflammatory factors and neurobehavior in different rat models...

2022-07-01
【Animal modeling】-Effect of hypoxia on the expressions of drug transporters MDR1 and MRP2 in rats

【Animal modeling】-Effect of hypoxia on the expressions of drug transporters MDR1 and MRP2 in rats

To study the effect of simulated rapid altitude hypoxia on some physiological indexes and the expression of MDR1 and MRP2 efflux drug transporters in the small intestine, liver and kidney of rats, and to preliminarily explore the effect of high altit...

2022-07-01
【Animal Modeling】-Transcranial ultrasound perfusion imaging performance and safety evaluation in rats after skull thinning

【Animal Modeling】-Transcranial ultrasound perfusion imaging performance and safety evaluation in rats after skull thinning

To observe and quantitatively evaluate the performance of right brain transcranial ultrasound perfusion imaging by thinning the local skull of SD rats to improve the acoustic window, and to preliminarily evaluate the effect of bone grinding and trans...

2022-07-01
【Animal Modeling】-Effect of ubiquitin carboxyl-terminal hydrolase 1 gene deletion on the reproductive system development of female mice

【Animal Modeling】-Effect of ubiquitin carboxyl-terminal hydrolase 1 gene deletion on the reproductive system development of female mice

To study the effect of ubiquitin carboxyl-terminal hydrolase L1 gene deletion on the reproductive system of female mice...

2022-07-01
【Animal modeling】-Protective effect of Paijiangcao on acetaminophen-induced drug-induced liver injury in rats

【Animal modeling】-Protective effect of Paijiangcao on acetaminophen-induced drug-induced liver injury in rats

Paijiangcao is the whole rooted herb of the perennial herbs of the family Paiaceae, Huanghuabaijiang and Baihuabaijiang, with various pharmacological activities. The purpose of this study was to investigate the protective effect of Patrinia on acetam...

2022-07-01