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【Animal modeling】-IVC cage changing standard operating procedures and the risk of transmission of mouse virus pathogens

【Animal modeling】-IVC cage changing standard operating procedures and the risk of transmission of mouse virus pathogens

To study the risk of virus infection in mice raised with IVC equipment in the standard operating procedure of cage changing in independent ventilation cages and laboratory animal negative pressure barrier facilities...

2022-05-07
【Animal Modeling】-Manufacture and Application of Laser Localizer for Experimental Animal Magnetic Resonance Imaging System

【Animal Modeling】-Manufacture and Application of Laser Localizer for Experimental Animal Magnetic Resonance Imaging System

To design and develop a simple laser locator for rats and mice, and to provide a safe, convenient, accurate, low-cost and easy-to-operate experimental tool for medical nuclear magnetic resonance experiments...

2022-05-07
【Animal Modeling】-Analysis of Main Nutrient Components and Amino Acid Composition of SPF Golden Hamster Milk

【Animal Modeling】-Analysis of Main Nutrient Components and Amino Acid Composition of SPF Golden Hamster Milk

To understand the composition of SPF golden hamster milk, and to compare it with other rodent (mouse, rat, guinea pig) milk, rabbit milk, cow milk and infant formula...

2022-05-07
【Animal Modeling】-Analysis of Spontaneous Lesions in Young SD Rats

【Animal Modeling】-Analysis of Spontaneous Lesions in Young SD Rats

To study the occurrence of spontaneous lesions in young SPF SD rats, and to provide data for the preclinical safety evaluation of drugs, especially the preclinical evaluation of pediatric drugs...

2022-05-07
【Animal modeling】-Gene cloning and preliminary functional study of junctional adhesion molecule A in tree ferrets

【Animal modeling】-Gene cloning and preliminary functional study of junctional adhesion molecule A in tree ferrets

To obtain the full-length coding sequence of junctional adhesion molecule A in tree ferrets and analyze its molecular characteristics, and to explore the mechanism of JAM-A as a receptor for reovirus invading primary lung cells of arborvitae...

2022-05-07
【Animal Modeling】-Establishment of real-time quantitative PCR method for mouse hepatitis virus and its application in some rodents

【Animal Modeling】-Establishment of real-time quantitative PCR method for mouse hepatitis virus and its application in some rodents

To establish a real-time quantitative PCR detection method for mouse hepatitis virus (MHV), and apply it to the detection of rodents such as nude-waisted mice...

2022-05-07
【Animal modeling】- Breeding and genotype identification of Bmal1 clock gene knockout mice

【Animal modeling】- Breeding and genotype identification of Bmal1 clock gene knockout mice

To breed and identify the genotype of Bmal1 knockout mice to provide an ideal animal model for biological rhythm research...

2022-05-07
【Animal modeling】-Effect of p53 knockout on neurobehavior and the number of neurons in barrel cortex in mice

【Animal modeling】-Effect of p53 knockout on neurobehavior and the number of neurons in barrel cortex in mice

To explore the role of p53 gene in neurobehavioral activity in mice and its effect on the number of neurons in barrel cortex...

2022-05-07
【Animal modeling】-Establishment and preliminary application of FO-PCR detection method for mouse pox virus

【Animal modeling】-Establishment and preliminary application of FO-PCR detection method for mouse pox virus

To establish a TaqMan probe-based fluorescent quantitative PCR detection method for mouse pox virus (ECTV), and to detect the nude mole rat tissue samples, mouse tissue samples and chinchilla tissue samples preserved in the laboratory...

2022-05-07
【Animal Modeling】-Relationship between vascular calcification and bone metabolism markers in rats with chronic kidney disease

【Animal Modeling】-Relationship between vascular calcification and bone metabolism markers in rats with chronic kidney disease

To study the correlation between vascular calcification and serum bone metabolism markers in chronic kidney disease (CKD) rats...

2022-05-07
【Animal Modeling】-Relationship between the expression of vitamin D metabolizing enzyme CYP24A1 in testis of adult tree shrew and fertility

【Animal Modeling】-Relationship between the expression of vitamin D metabolizing enzyme CYP24A1 in testis of adult tree shrew and fertility

To study the transcript levels of vitamin D metabolizing enzymes and vitamin D receptors in the testis of adult tree shrew, detect the protein expression of CYP24A1, and explore the causes of reproductive disorders in male experimental tree shrew...

2022-05-07
【Animal Modeling】-Analysis and establishment and hematopoietic phenotype of Marcksl1 knockout mice

【Animal Modeling】-Analysis and establishment and hematopoietic phenotype of Marcksl1 knockout mice

To establish Marcksl1 knockout mice, and to preliminarily explore the effect of this gene deletion on the development of hematopoietic system...

2022-05-07
【Animal modeling】-Prnp-SNCA-A53T Parkinson\'s disease transgenic mice with different intestinal flora

【Animal modeling】-Prnp-SNCA-A53T Parkinson's disease transgenic mice with different intestinal flora

A number of evidences indicate that the intestinal flora of Parkinson\'s disease patients is abnormal, and whether Prnp-SNCA-A53T Parkinson\'s disease transgenic mice also have intestinal flora dysbiosis has not been reported. Microbial ecological ch...

2022-05-07
【Animal modeling】-Isolation and identification of exosomes from skin fibroblasts of naked mole rats

【Animal modeling】-Isolation and identification of exosomes from skin fibroblasts of naked mole rats

To isolate and culture naked mole rat skin fibroblasts, identify them, and explore whether naked mole rat skin fibroblasts have the ability to secrete exosomes...

2022-05-06
【Animal Modeling】-Effect and mechanism of fine particulate matter PM2.5 on atherosclerosis in ApoE knockout mice

【Animal Modeling】-Effect and mechanism of fine particulate matter PM2.5 on atherosclerosis in ApoE knockout mice

The purpose of this experiment was to investigate the effect and mechanism of fine particulate matter PM2.5 on ApoE knockout (Apoe-/-) mice (atherosclerosis model mice)...

2022-05-06
【Animal Modeling】-Screening of polymorphic microsatellite loci of guinea pig individuals and strains

【Animal Modeling】-Screening of polymorphic microsatellite loci of guinea pig individuals and strains

To screen polymorphic microsatellite markers in guinea pigs and provide basic information for identifying the genetic structure and gene location of guinea pigs...

2022-05-06