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【Animal Modeling】-Long non-coding RNA TUG1 regulates the mechanism of miR-137 involved in nerve injury in rats with focal cerebral ischemia

【Animal Modeling】-Long non-coding RNA TUG1 regulates the mechanism of miR-137 involved in nerve injury in rats with focal cerebral ischemia

To investigate the role of long non-coding RNA (LncRNA) taurine up-regulated gene 1 (TUG1) regulating microRNA (miR)-137 involved in nerve injury in rats with focal cerebral ischemia...

2022-05-05
【Animal Modeling】-Effect and mechanism of propofol intervention on optic nerve injury in rats

【Animal Modeling】-Effect and mechanism of propofol intervention on optic nerve injury in rats

To investigate the effect and mechanism of propofol intervention on the injured optic nerve and retinal ganglia after optic nerve injury in rats...

2022-04-29
【Animal Modeling】-Screening and optimization of microsatellite loci in gerbils using genomic data

【Animal Modeling】-Screening and optimization of microsatellite loci in gerbils using genomic data

To use genomic data to screen more effective microsatellite loci of gerbils for genetic quality analysis of inbred lines and closed groups, and to enrich the genetic data of gerbils...

2022-04-29
【Animal modeling】-Proliferation and differentiation of endogenous neural stem cells in the subventricular zone after traumatic brain injury in rats

【Animal modeling】-Proliferation and differentiation of endogenous neural stem cells in the subventricular zone after traumatic brain injury in rats

To investigate the time course changes of the proliferation and differentiation of neural stem cells (NSCs) in the subventricular zone (SVZ) after traumatic brain injury...

2022-04-29
【Animal Modeling】-Analysis of basic physiological and biochemical indicators of male and female FMMU albino guinea pigs

【Animal Modeling】-Analysis of basic physiological and biochemical indicators of male and female FMMU albino guinea pigs

To measure and compare the blood indexes, heart rate, common carotid arterial pressure, ventricular pressure and organ parameters of female and male common-grade FMMU albino guinea pigs...

2022-04-28
【Animal modeling】-Optimization of in vivo chromosomal aberration test in ICR mice

【Animal modeling】-Optimization of in vivo chromosomal aberration test in ICR mice

To carry out in vivo chromosomal aberration experiments in ICR mice, by administering cyclophosphamide and colchicine at different time points, to compare the effects of different administration/collection time points and different administration con...

2022-04-28
【Animal Modeling】-Effect of first mating age on reproductive performance of NIH mice

【Animal Modeling】-Effect of first mating age on reproductive performance of NIH mice

To systematically study the effects of different first mating days on the reproductive performance of NIH mice...

2022-04-28
【Animal modeling】-Protective effect of liraglutide on stress-stressed chronic heart failure in rats

【Animal modeling】-Protective effect of liraglutide on stress-stressed chronic heart failure in rats

To study the effect and mechanism of liraglutide on cardiac function in pressure-stressed chronic heart failure rats...

2022-04-28
【Animal modeling】-Effect of percutaneous electrical stimulation on end-to-side anastomosis of peripheral nerves in rats

【Animal modeling】-Effect of percutaneous electrical stimulation on end-to-side anastomosis of peripheral nerves in rats

To observe and explore the effect of percutaneous electrical stimulation on nerve regeneration after nerve end-to-side anastomosis and its clinical value...

2022-04-28
【Animal modeling】-Effect of Jiuxieling granules on the expression of TLR4 and NF-κB p65 in rats with ulcerative colitis of spleen and kidney yang deficiency

【Animal modeling】-Effect of Jiuxieling granules on the expression of TLR4 and NF-κB p65 in rats with ulcerative colitis of spleen and kidney yang deficiency

To investigate the effect of Jiuxieling Granules on the expression of TLR4 and NF-κB p65 protein genes in colon tissue of rats with ulcerative colitis due to spleen and kidney yang deficiency...

2022-04-28
【Animal Modeling】-Inhibition of PAR2-PKA/PKCε pathway in peripheral neurons affects pain threshold in rats with pain transformation

【Animal Modeling】-Inhibition of PAR2-PKA/PKCε pathway in peripheral neurons affects pain threshold in rats with pain transformation

To investigate the role of peripheral neuron protease-activated receptor 2-protein kinase A/protein kinase Cε (PAR2-PKA/PKCε) pathway in pain transformation, and to find a possible solution to simultaneously intervene in acute pain and chronic pain...

2022-04-28
【Animal modeling】-Evaluation of mouse renal ischemia-reperfusion injury by combining ultrasound radiation force with targeted ultrasound microbubbles

【Animal modeling】-Evaluation of mouse renal ischemia-reperfusion injury by combining ultrasound radiation force with targeted ultrasound microbubbles

  Study ultrasound radiation to promote the adhesion of target microbubbles and improve the sensitivity and feasibility of renal ischemia-reperfusion injury detection...

2022-04-28
【Animal modeling】-Expression and significance of basic leucine zipper transcription factor ATF-like protein in kidney tissue of lupus mice

【Animal modeling】-Expression and significance of basic leucine zipper transcription factor ATF-like protein in kidney tissue of lupus mice

To investigate the expression and clinical significance of basic leucine zipper transcription factor ATF-like protein in kidney tissue of lupus mice...

2022-04-28
【Animal modeling】-Effect of hypoxia on the expressions of drug transporters MDR1 and MRP2 in rats

【Animal modeling】-Effect of hypoxia on the expressions of drug transporters MDR1 and MRP2 in rats

To study the effect of simulated rapid altitude hypoxia on some physiological indexes and the expression of MDR1 and MRP2 efflux drug transporters in the small intestine, liver and kidney of rats, and to preliminarily explore the effect of high altit...

2022-04-28
【Animal modeling】-Effect of Ghrelin on the expression of DKK-1 in the hippocampus and learning and memory function of diabetic rats

【Animal modeling】-Effect of Ghrelin on the expression of DKK-1 in the hippocampus and learning and memory function of diabetic rats

To observe the expression changes of Ghrelin on DKK-1 and WNT signaling pathways in diabetic rats, and to explore the mechanism involved in learning and memory function...

2022-04-28
【Animal Modeling】-Analysis of Bacterial Community Diversity in Large Intestine Contents of Tree Shrews

【Animal Modeling】-Analysis of Bacterial Community Diversity in Large Intestine Contents of Tree Shrews

To analyze the structure and composition of E. coli bacteria in tree shrew by high-throughput sequencing technology...

2022-04-28