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Phase III clinical trials show that olaparib, used in the treatment of breast and ovarian cancer, will lead to changes in the treatment of advanced prostate cancer

Phase III clinical trials show that olaparib, used in the treatment of breast and ovarian cancer, will lead to changes in the treatment of advanced prostate cancer

In a phase III clinical trial that changes clinical practice, drugs used to treat breast and ovarian cancer can extend the lifespan of certain men with prostate cancer, making it a new standard treatment for the disease...

2020-10-30
New 3D tumor models developed in the laboratory may help improve therapies for ovarian cancer

New 3D tumor models developed in the laboratory may help improve therapies for ovarian cancer

In the latest research report published in the international journal \"Science Advances\", scientists from the University of Nottingham and other institutions studied the 3D tumor model of ovarian cancer in the laboratory through research...

2020-10-30
Reveal the structural mechanism of nucleosomes inhibiting cGAS

Reveal the structural mechanism of nucleosomes inhibiting cGAS

In all mammals, cyclic GMP-AMP synthase (cGAS) can sense the invasion of pathogenic DNA and stimulate inflammation signals, autophagy and apoptosis...

2020-10-30
Revealing the structural mechanism of SARS-CoV-2 spike protein binding to human ACE2 receptor

Revealing the structural mechanism of SARS-CoV-2 spike protein binding to human ACE2 receptor

In a new study, researchers from the Francis-Crick Institute in the United Kingdom found that the spike protein (S protein) on the surface of the SARS-CoV-2 coronavirus can be used when it comes into contact with the human virus receptor ACE2. At lea...

2020-10-30
Tsinghua University and Zhejiang University join forces to reveal the molecular structure of the new coronavirus

Tsinghua University and Zhejiang University join forces to reveal the molecular structure of the new coronavirus

The new coronavirus SARS-CoV-2 caused Coronavirus Disease (COVID-19) in 2019 and is currently rampant around the world....

2020-10-30
Reveal the neutralization site and immunodominant site of the RBD domain of the new coronavirus S protein

Reveal the neutralization site and immunodominant site of the RBD domain of the new coronavirus S protein

The new coronavirus SARS-CoV-2 caused Coronavirus Disease (COVID-19) in 2019 and is currently rampant around the world....

2020-10-30
Chinese scientists structurally reveal that BD-368-2 antibody can effectively treat hamsters severely infected by the new coronavirus

Chinese scientists structurally reveal that BD-368-2 antibody can effectively treat hamsters severely infected by the new coronavirus

Understanding how effective neutralizing antibodies (NAbs) inhibit SARS-CoV-2 is the key to developing effective therapies. In a previous new study, using the expertise of single-cell genomics, Peking University Beijing Advanced Innovation Center for...

2020-10-30
Analysis of the structure and function of the SARS-CoV-2 spike protein variant D614G

Analysis of the structure and function of the SARS-CoV-2 spike protein variant D614G

Since December 8, 2019, several cases of pneumonia of unknown etiology have been reported in Wuhan City, Hubei Province, China. Most patients work or live near the local Huanan Seafood Wholesale Market...

2020-10-30
Solve the three-dimensional structure of the BAF complex in human cells

Solve the three-dimensional structure of the BAF complex in human cells

A key molecular \\\"machine\\\" called the BAF complex can change the structure of DNA, and mutations often occur in cancer and other diseases...

2020-10-30
Susceptible cells may be able to protect themselves from pathogen infection by removing cholesterol on the cell surface

Susceptible cells may be able to protect themselves from pathogen infection by removing cholesterol on the cell surface

A few days ago, in a research report published in the international journal Nature Microbiology, scientists at the University of Texas Southwestern Medical Center and other institutions found that when the immune system detects danger, certain bodies...

2020-10-30
Cholesterol drugs can effectively alleviate the spread of breast cancer cells to the brain

Cholesterol drugs can effectively alleviate the spread of breast cancer cells to the brain

A new study by the University of Notre Dame in Paris shows that drugs used to treat high cholesterol may interfere with the way breast cancer cells adapt to the brain microenvironment, thereby preventing the spread of cancer to the brain...

2020-10-30
Blocking cellular cholesterol storage may be expected to inhibit the progression of pancreatic cancer

Blocking cellular cholesterol storage may be expected to inhibit the progression of pancreatic cancer

In a research report recently published in the International Journal of Experimental Medicine, scientists from the Cold Spring Harbor Institute and other institutions studied mouse and laboratory-grown pancreatic tissue models to show how cells store...

2020-10-30
\"Good cholesterol\" can be used to predict the risk of heart disease and stroke

"Good cholesterol" can be used to predict the risk of heart disease and stroke

High-density lipoprotein (HDL) cholesterol has been called \"good cholesterol\" for decades because it can remove fat and other cholesterol molecules from artery walls...

2020-10-30
Research reveals the effect of cholesterol on cell membranes

Research reveals the effect of cholesterol on cell membranes

For more than a decade, scientists have admitted that cholesterol (an important part of cell membranes) cannot uniformly affect different types of membranes...

2020-10-30
Reveal the mechanism that cholesterol-25-hydroxylase inhibits SARS-CoV-2 and other coronavirus infections

Reveal the mechanism that cholesterol-25-hydroxylase inhibits SARS-CoV-2 and other coronavirus infections

The new coronavirus SARS-CoV-2 caused Coronavirus Disease (COVID-19) in 2019 and is currently rampant around the world....

2020-10-30
Demystifying the mysterious link between obesity and cancer metastasis

Demystifying the mysterious link between obesity and cancer metastasis

Recently, scientists from Tufts University and other institutions have revealed the relationship between obesity and cancer metastasis through research...

2020-10-29