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In the field of medical and biological research, especially in the safety assessment of tumors, immunity, drugs, biologics, and preclinical screening of effective drugs, NudeMouse (\"naked mice\") has always been an indispensable experiment...
2020-07-23Spinal cord injury (SCI) is caused by the displacement of herniated bone fragments in the vertebral body or spinal canal, causing varying degrees of damage to the spinal cord or cauda equina, as well as changes in motor, sensory and sphincter functio...
2020-07-23
Reviewing the data collected from the review and the summary of Table 11 at the end of the review, we can see that the choice of the appropriate system is different, as long as the metabolism of the compound under consideration involves different enz...
2020-07-23
Zika virus (ZIKV) infection is a major public health problem in the world. The World Health Organization has declared Zika virus a “public health emergency of international concern”. In 2015, Zika disease broke out in Brazil, where a large number of ...
2020-07-23Type 1 (HSV-1) and type 2 (HSV-2) herpes simplex virus (HSV) infections are the most common human infections. The herpes simplex virus usually causes self-limiting oral and genital bullous ulcers that often recur. However, HSV can cause more serious ...
2020-07-23Although the national epidemic gradually disappeared, the epidemic in Beijing \"rebounded\" and affected the hearts of people across the country. During active screening, several asymptomatic carriers were found. This must have taught us al...
2020-07-23Recently, in the fight against the global pandemic, exciting innovations have inspired the world, and the world has successfully established a new coronavirus animal model! The mission of the Institute of Animal Science of the Chinese Academy of Medi...
2020-07-23Non-alcoholic fatty liver disease (NAFLD) is a liver syndrome without alcohol abuse, including simple fatty liver, steatohepatitis, fatty liver fibrosis and cirrhosis. It can range from simple fatty liver to non-alcoholic steatohepatitis (NASH) to li...
2020-07-23
Human viral diseases include Creutzfeldt-Jakob disease (CJD) and Gerstmann syndrome (GSS). Scientists from University College London and other institutions recently published a research report in the international journal PLoSBiology, which is based ...
2020-07-23Retinal vascular diseases, such as exudative age-related macular degeneration (eAMD), diabetic macular edema (DME), and proliferative diabetic retinopathy (PDR), all cause persistent and progressive vascular leakage. The disease indicates leakage and...
2020-07-23
Atherosclerosis is the most common underlying cause of cardiovascular disease in many people, and the main cause of morbidity and mortality. Atherosclerosis is a chronic inflammatory process involving multiple cell types and cytokines. Its developmen...
2020-07-22
The global research and development of the new global coronavirus vaccine has made considerable progress, and vaccines prepared through various technical methods have entered phase II clinical trials. However, the relative lack of animal models has h...
2020-07-22Biomedicine has always been a world dominated by men, which is not only reflected in the vast majority of researchers engaged in biomedical research, but also in the laboratory animals they use. This number far exceeds that of women....
2020-07-22In the 17th century, mice began to be used in animal modeling. Today, the mouse has become the most widely used and detailed experimental animal. However, since mice have no sweat glands and prefer to live in a dark environment that is less adapted t...
2020-07-22At the end of the 19th century, the application of animal-derived serum to treat infections in animal experiments was the first attempt to develop antibody drugs. The successful establishment of hybridoma technology in 1975 greatly promoted the devel...
2020-07-22How many years has your pet dog been with you? According to the famous \"dog\'s age rule\", a dog\'s year is equal to a person\'s seven years. A study published in \"Cell Systems\" (CellPress Cell Press) on July 2 shows that this ...
2020-07-22