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What are the limitations of animal models of infectious diseases?

What are the limitations of animal models of infectious diseases?

After all, infectious animal models use animals for artificial infections and simulation studies. In particular, pathogens of human origin infect animals...

2020-07-24
【Animal Modeling】-Testing of Genetic Quality of Laboratory Animals

【Animal Modeling】-Testing of Genetic Quality of Laboratory Animals

Significance The genetic testing of experimental animals is mainly the genetic testing of experimental mice. Since the use of laboratory mice as research tools, people have bred many laboratory strains, and these strains are now distributed all over...

2020-07-24
Preparation of H5N1 virus infection BALB/c mouse model

Preparation of H5N1 virus infection BALB/c mouse model

The design, observation, sampling and detection methods of BALB/c mouse infection: 4-6 weeks old BALB/c mice weighing 18-18 g were selected. Instill 100 TCID50 virus (50 μl volume) into each animal through the nasal cavity. 5 birds/cage, drink water ...

2020-07-24
【Animal Modeling】-Aluminum hydroxide induced chronic epilepsy model

【Animal Modeling】-Aluminum hydroxide induced chronic epilepsy model

1. Material animal model: rhesus monkey, medicine: aluminum hydroxide, anesthetic....

2020-07-24
【Animal Modeling】-Cobalt-induced chronic epilepsy model

【Animal Modeling】-Cobalt-induced chronic epilepsy model

1. Model material: rat; drug: pentobarbital, cobalt powder, kanamycin; instrument: stereotaxic device....

2020-07-24
Heating, air conditioning, ventilation and air purification systems in animal laboratories

Heating, air conditioning, ventilation and air purification systems in animal laboratories

The environmental requirements of animal laboratories depend on the laboratory level. According to the classification of laboratory environment facilities, animal laboratories are divided into three levels: normal environment, isolated environment an...

2020-07-24
Construction process of Zhonghong Boyuan laboratory animal facilities

Construction process of Zhonghong Boyuan laboratory animal facilities

In the planning and project approval of laboratory animal facilities, in addition to following the above basic principles, the following requirements should also be fully considered from the planning stage....

2020-07-24
Genetic Quality Control of Laboratory Animals in Closed Group

Genetic Quality Control of Laboratory Animals in Closed Group

Losedcolony is a group of animals with different genotypes, also known as inbred species. This refers to a group of experimental animals that are reproduced and produced by hybrids without introducing new animals from outside. Individual circumstance...

2020-07-24
How to control the genetic quality of inbred experimental animals?

How to control the genetic quality of inbred experimental animals?

Inbreeding refers to the mating of all siblings in 20 consecutive generations. All individuals in succession can be traced back to paired common ancestors that have appeared since 20 generations. After more than 20 consecutive parents and offspring h...

2020-07-24
How is the genetics of laboratory animals classified?

How is the genetics of laboratory animals classified?

From a genetics point of view, laboratory animals are genetically restricted animals. According to different genetic characteristics, the experimental animals are divided into inbred, closed and hybrid groups. According to the degree of homozygous ge...

2020-07-24
Mitochondrial ultrastructure data of photoreceptor cells in pig, rabbit and mouse retina

Mitochondrial ultrastructure data of photoreceptor cells in pig, rabbit and mouse retina

According to reports, the pig retina contains a large number of mitochondria. Since there are few reports of large mitochondria in mammalian photoreceptors, scanning electron microscopy (SEM) was used to evaluate the morphology of pig, rabbit, and mo...

2020-07-24
【Animal Experiment】-The effects of four organic solvents on zebrafish eye development

【Animal Experiment】-The effects of four organic solvents on zebrafish eye development

Objective To evaluate the effects of ethanol, isopropanol, acetone and dimethyl sulfoxide on zebrafish embryonic development, especially eye development, and to provide references for its application in the study of zebrafish eye disease models....

2020-07-24
The newly discovered swine flu virus in China may cause a human flu pandemic!

The newly discovered swine flu virus in China may cause a human flu pandemic!

Pigs are considered to be an important host or \"mixing container\" for the production of pandemic influenza viruses. Systematic surveillance of swine flu viruses is essential for early warning and prevention of the next pandemic....

2020-07-24
【Zhonghong Boyuan】-Establishment of acute and chronic hyperuricemia animal models

【Zhonghong Boyuan】-Establishment of acute and chronic hyperuricemia animal models

Objective: To establish acute and chronic hyperuricemia models in rats, use positive drugs to verify the sclerosis of the two models, and provide model tools for the development of anti-hyperuric acid drugs....

2020-07-23
Interpretation of simulated human primate aging model

Interpretation of simulated human primate aging model

Simulating human aging: Ideally, all biomedical research related to humans should be conducted in humans, but due to many ethical and technical considerations, this is obviously unrealistic. Therefore, it is necessary to model human aging in non-huma...

2020-07-23
Mouse model uses cell therapy to complete axon remyelination

Mouse model uses cell therapy to complete axon remyelination

\\\"Demyelination diseases, such as multiple sclerosis and leukocyte dystrophy, are characterized by the destruction of the protective myelin sheath surrounding axons. This demyelination phenomenon may be due to autoimmune reactions or the myeli...

2020-07-23