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【Animal Modeling】-Effect of DPP4 inhibitor sitagliptin on the expression of Egr-1 and FN in the kidney of ApoE knockout mice

【Animal Modeling】-Effect of DPP4 inhibitor sitagliptin on the expression of Egr-1 and FN in the kidney of ApoE knockout mice

To observe the effect of DPP4 inhibitor sitagliptin on the expression of early growth response factor-1 (Egr-1) and fibronectin (FN) in kidney tissue of ApoE knockout mice...

2022-07-12
【Animal Modeling】-Intervention and Mechanism of Low Molecular Weight Heparin Calcium on Mouse Embryonic Implantation

【Animal Modeling】-Intervention and Mechanism of Low Molecular Weight Heparin Calcium on Mouse Embryonic Implantation

To investigate the intervention effect and mechanism of low molecular weight heparin calcium on mouse embryo implantation...

2022-07-12
【Animal modeling】-Effect of fluoxetine on behavior and hippocampal neurogenesis in post-stroke depression model rats

【Animal modeling】-Effect of fluoxetine on behavior and hippocampal neurogenesis in post-stroke depression model rats

To explore the effect of fluoxetine on behavior and hippocampal neurogenesis in post-stroke depression model rats...

2022-07-12
【Animal Modeling】-Influence of inflammatory factor storm on immune response to infection in aged mice

【Animal Modeling】-Influence of inflammatory factor storm on immune response to infection in aged mice

After highly pathogenic avian influenza infects mice, over-expressed inflammatory factors, namely inflammatory factor storm, are detected in the lungs. A high level of inflammatory response is more common in elderly infected patients. This paper expl...

2022-07-12
【Animal modeling】-Exploration of the protective effect of bifidobacteria on liver function in rats with chronic alcoholic liver injury

【Animal modeling】-Exploration of the protective effect of bifidobacteria on liver function in rats with chronic alcoholic liver injury

To investigate the protective or influence of bifidobacteria on liver function in rats with chronic alcoholic liver injury, and to explore its mechanism preliminarily...

2022-07-12
【Animal modeling】-Effect of repeated propofol anesthesia on spatial memory and long-term enhancement in young rats under hypoxia

【Animal modeling】-Effect of repeated propofol anesthesia on spatial memory and long-term enhancement in young rats under hypoxia

Propofol is the most commonly used intravenous anesthesia for induction and maintenance anesthesia...

2022-07-12
【Animal modeling】-Effect of maca combined with exercise therapy on renal mitochondrial respiratory chain enzyme activity and renal function in diabetic rats

【Animal modeling】-Effect of maca combined with exercise therapy on renal mitochondrial respiratory chain enzyme activity and renal function in diabetic rats

To observe the effect of maca combined with exercise therapy on renal mitochondrial respiratory enzyme activity and renal function in diabetic rats...

2022-07-12
【Animal modeling】-Application of mouse regional lymph node test in skin sensitization detection of 25% Cyhalofop-butyl EC

【Animal modeling】-Application of mouse regional lymph node test in skin sensitization detection of 25% Cyhalofop-butyl EC

To detect the sensitization of 25% Cyhalofop-ethyl EC by mouse regional lymph node assay (BrdU-ELISA)...

2022-07-12
【Animal modeling】-Effect of Astragalus on endoplasmic reticulum stress response in vascular remodeling in hypertensive rats

【Animal modeling】-Effect of Astragalus on endoplasmic reticulum stress response in vascular remodeling in hypertensive rats

To study the effect of Astragalus on endoplasmic reticulum stress response (ERS) in vascular remodeling in hypertensive rats, and to explore the molecular mechanism of its vascular protection...

2022-07-12
【Animal modeling】-Effect of rosuvastatin on myocardial matrix metalloproteins and inflammatory factors in rats with acute myocardial infarction

【Animal modeling】-Effect of rosuvastatin on myocardial matrix metalloproteins and inflammatory factors in rats with acute myocardial infarction

To observe the changes of matrix metalloproteinase MMPs, TIMP2 and inflammatory factors TNF-α and IL-1β in myocardial tissue of rats with acute myocardial infarction (AMI) treated with rosuvastatin...

2022-07-12
【Animal modeling】-Study on the protective effect of salvianolic acid A on the kidney of ZDF rats and the inhibition of lipoprotein-associated phospholipase A2

【Animal modeling】-Study on the protective effect of salvianolic acid A on the kidney of ZDF rats and the inhibition of lipoprotein-associated phospholipase A2

To observe the protective effect of salvianolic acid A on nephropathy in Zucker diabetic obese rats and its effect on the expression of lipoprotein-related phospholipase A2...

2022-07-12
【Animal modeling】-Study on the protective effect of morroniside administered 24 hours after operation on focal cerebral ischemia-reperfusion in rats

【Animal modeling】-Study on the protective effect of morroniside administered 24 hours after operation on focal cerebral ischemia-reperfusion in rats

To study the effect of morroniside on angiogenesis-related factors and neurological function 24 hours after focal cerebral ischemia-reperfusion in rats...

2022-07-12
【Animal Modeling】-Effects of chronic arsenic exposure on brain and serum metabolomics in mice

【Animal Modeling】-Effects of chronic arsenic exposure on brain and serum metabolomics in mice

To observe the effects of chronic arsenic exposure on the metabolomics of mouse cortex and serum, and to explore its neurotoxicity mechanism...

2022-07-12
【Animal Modeling】-Effects of experimental intervention of normal saline on caecal microflora and short-chain fatty acid content in broilers

【Animal Modeling】-Effects of experimental intervention of normal saline on caecal microflora and short-chain fatty acid content in broilers

To study the effects of experimental intervention of normal saline on the microflora and content of short-chain fatty acids in the caecum of broilers, in order to provide a theoretical basis for the study of early microbiota intervention experiments...

2022-07-12
【Animal Modeling】-Anti-depressant effect of luteolin on chronic unpredictable mild stress mice

【Animal Modeling】-Anti-depressant effect of luteolin on chronic unpredictable mild stress mice

To observe the effect of hyaluronan on antidepressant, and to preliminarily explore its possible mechanism of action...

2022-07-12
【Animal modeling】-Protective effect of curcumin on renal fibrosis in 5/6 kidney ligation-induced chronic kidney disease mouse model

【Animal modeling】-Protective effect of curcumin on renal fibrosis in 5/6 kidney ligation-induced chronic kidney disease mouse model

To study the protective effect of curcumin on renal fibrosis in chronic kidney disease, and to explore the possible mechanism of action...

2022-07-12