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【Animal modeling】-Screening EV71 pathogenic related genes by genetically diverse mice

【Animal modeling】-Screening EV71 pathogenic related genes by genetically diverse mice

To screen the pathogenic related genes of enterovirus 71 through genetically diverse mouse resources, to deeply understand the pathogenic mechanism of the virus, and to provide the basis for clinical diagnosis, treatment and prognosis...

2022-07-12
【Animal modeling】-Analysis of the effects of calcium and vitamin D dietary supplementation on osteoclast activity and bone mass in a rat ankle fracture trauma model

【Animal modeling】-Analysis of the effects of calcium and vitamin D dietary supplementation on osteoclast activity and bone mass in a rat ankle fracture trauma model

To investigate the effect of calcium and vitamin D (Ca/VitD) diet on osteoclast activity and bone mass in a rat ankle fracture trauma model...

2022-07-12
【Animal Modeling】-Comparison of the pressure of goat maxillary sinus and frontal sinus mucosa

【Animal Modeling】-Comparison of the pressure of goat maxillary sinus and frontal sinus mucosa

To investigate the difference in pressure tolerance of goat sinus (maxillary sinus and frontal sinus) mucosa and analyze the reasons for the difference, so as to provide theoretical basis and guidance for mucosal problems during maxillary sinus floor...

2022-07-12
【Animal modeling】-Effect of IGF-1 gene and electrical stimulation therapy on rat model of postpartum stress urinary incontinence

【Animal modeling】-Effect of IGF-1 gene and electrical stimulation therapy on rat model of postpartum stress urinary incontinence

To study the effect of IGF-1 gene therapy on the rat model of postpartum stress urinary incontinence, and to explore the ideal treatment method for the disease...

2022-07-12
【Animal Modeling】-Human retinal graft improves visual acuity in a rat model of severe retinal degeneration

【Animal Modeling】-Human retinal graft improves visual acuity in a rat model of severe retinal degeneration

Age-related macular degeneration, Stargardt disease, and retinitis pigmentosa are common RD disorders that often lead to irreversible blindness...

2022-07-12
【Animal Modeling】-High-fat and high-purine diet combined with potassium oxonate induces glucose and lipid metabolism disorder and its complications in quail

【Animal Modeling】-High-fat and high-purine diet combined with potassium oxonate induces glucose and lipid metabolism disorder and its complications in quail

To establish a practical animal model of chronic metabolic diseases, and to explore the correlation between hyperuricemia and glucose and lipid metabolism, as well as its pathological damage mechanism...

2022-07-12
【Animal modeling】-Effect of N-acetylcysteine on hepatic oxidative stress and FoxO1 activity in type 2 diabetic rats

【Animal modeling】-Effect of N-acetylcysteine on hepatic oxidative stress and FoxO1 activity in type 2 diabetic rats

To investigate the effect of antioxidant N-acetylcysteine on hepatic oxidative stress and FoxO1 activity in type 2 diabetic rats...

2022-07-12
【Animal modeling】-Edaravone can reduce oxidative stress and delay myocardial fibrosis in rats

【Animal modeling】-Edaravone can reduce oxidative stress and delay myocardial fibrosis in rats

To investigate the effect of edaravone on reducing oxidative stress and anti-myocardial fibrosis...

2022-07-12
【Animal Model】-Long-term effects of sublethal dose of γ-ray whole body irradiation on hematopoietic immune function in mice

【Animal Model】-Long-term effects of sublethal dose of γ-ray whole body irradiation on hematopoietic immune function in mice

To observe the changes of hematopoietic and immune function indexes in C57BL/6J mice 6 months after total body irradiation with 4Gy and 6Gy...

2022-07-12
【Animal modeling】-Pathological observation of renal artery embolism by microsphere embolization agent in Beagle dogs

【Animal modeling】-Pathological observation of renal artery embolism by microsphere embolization agent in Beagle dogs

To establish a model of canine renal artery embolization with microsphere embolization agent, and to evaluate the effect of unilateral renal artery embolization and local tissue observation...

2022-07-12
【Animal Modeling】-Effect of Qingzao Jiufei Decoction and its decomposers on pulmonary inflammation-related factors in mice infected with Mycoplasma pneumoniae

【Animal Modeling】-Effect of Qingzao Jiufei Decoction and its decomposers on pulmonary inflammation-related factors in mice infected with Mycoplasma pneumoniae

To investigate the effect of Qingzao Jiufei Decoction (QJD) and its decomposers on the content of TNF-α?INF-γ in serum and the expression of MPN372?P1?AQP5 in lung tissue of mice infected with Mycoplasma pneumoniae (MP), and to clarify its anti-infla...

2022-07-12
【Animal Modeling】-Protective effect of Shenmai on brain tissue of mice with acute cerebral infarction and its related mechanism

【Animal Modeling】-Protective effect of Shenmai on brain tissue of mice with acute cerebral infarction and its related mechanism

To study the protective effect of Shenmai injection on brain tissue in mice with acute cerebral infarction and to preliminarily explore its possible mechanism...

2022-07-11
【Animal Modeling】-Comparison of three methods of tracheal infusion of bleomycin to induce pulmonary fibrosis in mice

【Animal Modeling】-Comparison of three methods of tracheal infusion of bleomycin to induce pulmonary fibrosis in mice

To inject bleomycin into C57BL/6J mice to induce pulmonary fibrosis by three different methods: lumbar puncture tracheal intubation, indwelling needle tracheal intubation and tracheotomy, and to explore the modeling of lumbar puncture tracheal intuba...

2022-07-11
【Animal modeling】-Effect of curcumin on glucose transport and PI3K/Akt signaling pathway in adipocytes of type 2 diabetic rats

【Animal modeling】-Effect of curcumin on glucose transport and PI3K/Akt signaling pathway in adipocytes of type 2 diabetic rats

To investigate the effect of curcumin on glucose transport and phosphatidylinositol kinase-3 (PI3K)/protein kinase B (Akt) signaling pathway in adipocytes of type 2 diabetes mellitus (T2DM) rats...

2022-07-11
【Animal modeling】-Experimental observation of porcine circovirus type 3 infection in BALB/c mice

【Animal modeling】-Experimental observation of porcine circovirus type 3 infection in BALB/c mice

To study the infection of porcine circovirus type 3 in BALB/c mice...

2022-07-11
【Animal Modeling】-Application of Micro-arc Oxidation and Alkali Treatment Technology in Repairing Rabbit Skull Defect with Porous Tantalum

【Animal Modeling】-Application of Micro-arc Oxidation and Alkali Treatment Technology in Repairing Rabbit Skull Defect with Porous Tantalum

To observe the effects of micro-arc oxidation and alkali treatment on the surface properties, biocompatibility and osteogenic ability of porous tantalum...

2022-07-11