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【Animal modeling】-Protective effect of trigonelline on testicular injury induced by heat stress in mice

【Animal modeling】-Protective effect of trigonelline on testicular injury induced by heat stress in mice

To study the protective effect of trigonelline on heat stress-induced testicular injury in mice...

2022-06-28
【Animal Modeling】-Effect of high-fat diet-induced obesity on ovarian function in female reproductive rats

【Animal Modeling】-Effect of high-fat diet-induced obesity on ovarian function in female reproductive rats

To evaluate the effect of high-fat diet-induced obesity on ovarian function in female rats, and to explore its mechanism...

2022-06-28
【Animal Modeling】-Effect of chronic PM2.5 exposure on lung inflammation and NLRP3 inflammasome activity in C57BL/6J mice

【Animal Modeling】-Effect of chronic PM2.5 exposure on lung inflammation and NLRP3 inflammasome activity in C57BL/6J mice

To study the effects of chronic PM2.5 exposure on pneumonia and NLRP3 inflammasome activity in mice, and to provide new targets for the prevention and treatment of PM2.5-induced lung injury...

2022-06-28
【Animal Modeling】-Therapeutic effect of puerarin on acute liver failure in mice and its mechanism of action

【Animal Modeling】-Therapeutic effect of puerarin on acute liver failure in mice and its mechanism of action

To investigate the protective effect of puerarin on D-galactosamine-induced acute liver failure (ALF) in mice and to preliminarily observe its mechanism...

2022-06-28
【Animal Modeling】-Effect of psycho-dependent heroin on embryonic development and Bax expression in brain tissue of rats

【Animal Modeling】-Effect of psycho-dependent heroin on embryonic development and Bax expression in brain tissue of rats

To investigate the effect of heroin, a psychotropic substance, on the development of embryonic rats and the expression of Bax in the brain...

2022-06-28
【Animal modeling】-The effect of amputation trauma on cardiac electrophysiology, cardiac function and eNOS pathway in rats

【Animal modeling】-The effect of amputation trauma on cardiac electrophysiology, cardiac function and eNOS pathway in rats

To investigate the changes of cardiac electrophysiology and cardiac function after amputation in rats and their relationship with endothelial nitric oxide synthase/nitric oxide (eNOS/NO) pathway...

2022-06-28
【Animal Modeling】-The changes of cytokines in the process of hepatocellular carcinoma in rats with oxymatrine combined with all-trans retinoic acid

【Animal Modeling】-The changes of cytokines in the process of hepatocellular carcinoma in rats with oxymatrine combined with all-trans retinoic acid

To observe the effect of oxymatrine combined with all-trans retinoic acid in inhibiting the formation of liver cancer in rats induced by diethylnitrosamine (DEN), and to explore its mechanism...

2022-06-28
【Animal Modeling】-The regulatory mechanism of peripheral pain sensation in rats based on the interaction of TRPV1 and P2X3

【Animal Modeling】-The regulatory mechanism of peripheral pain sensation in rats based on the interaction of TRPV1 and P2X3

To observe the relationship between peripheral TRPV1 and P2X3 in rats, in order to partially elucidate the regulatory mechanism of peripheral pain sensation...

2022-06-28
【Animal modeling】-Effect of -FOXO3A on radiation injury of hematopoietic system in mice with total body irradiation

【Animal modeling】-Effect of -FOXO3A on radiation injury of hematopoietic system in mice with total body irradiation

To investigate the effect of FOXO3A on ionizing radiation injury in the hematopoietic system using FOXO3A knockout mice...

2022-06-27
【Animal modeling】-Effect of a compound Chinese medicine prescription on lung injury in mice infected with influenza virus A/PR/8/H1N1

【Animal modeling】-Effect of a compound Chinese medicine prescription on lung injury in mice infected with influenza virus A/PR/8/H1N1

To observe the effect of a compound Chinese medicine prescription on lung injury in mice infected with influenza virus A/PR/8/H1N1...

2022-06-27
【Animal Modeling】-Effect of total alkaloids of Dendrobium officinale on insulin resistance in diabetic rats with non-alcoholic fatty liver disease

【Animal Modeling】-Effect of total alkaloids of Dendrobium officinale on insulin resistance in diabetic rats with non-alcoholic fatty liver disease

To study the effect of total alkaloids of Dendrobium officinale on insulin resistance in diabetic rats with non-alcoholic fatty liver disease (NAFLD)...

2022-06-27
【Animal Modeling】-The effect of rapid modeling of KK mouse diet on related indicators of KK/Upj-Ay/J mice

【Animal Modeling】-The effect of rapid modeling of KK mouse diet on related indicators of KK/Upj-Ay/J mice

To study the rapid modeling of KK mouse diet and its effect on related indexes in KK/Upj-Ay/J mice...

2022-06-27
【Animal modeling】-Effect of lamotrigine on the expression of PGP, MVP and amino acid content in the hippocampus of chronic epilepsy rats

【Animal modeling】-Effect of lamotrigine on the expression of PGP, MVP and amino acid content in the hippocampus of chronic epilepsy rats

To investigate the effect of lamotrigine on the expression and amino acid content of P-glycoprotein and main vault protein in the hippocampus of chronic epilepsy rats...

2022-06-27
【Animal Modeling】-Protein Transformation Regulation Mechanism of Rat Skeletal Muscle Atrophy Induced by Hypoxia Exposure

【Animal Modeling】-Protein Transformation Regulation Mechanism of Rat Skeletal Muscle Atrophy Induced by Hypoxia Exposure

To compare the expression of genes related to protein synthesis and decomposition in skeletal muscle of rats under hypoxia exposure and normoxia paired with hypoxic feeding intervention (semi-starvation state), in order to explore the possible mechan...

2022-06-27
【Animal Modeling】-Effect of fasting time on glucose tolerance and insulin secretion in Kunming mice

【Animal Modeling】-Effect of fasting time on glucose tolerance and insulin secretion in Kunming mice

In order to explore the stable, reliable and reasonable fasting time of OGTT in Kunming mice, which are used the most in China in a specific environment...

2022-06-27
【Animal Modeling】-Human umbilical cord mesenchymal stem cell transplantation repairs premature ovarian failure in rats

【Animal Modeling】-Human umbilical cord mesenchymal stem cell transplantation repairs premature ovarian failure in rats

To investigate the mechanism of transplantation of human umbilical cord mesenchymal stem cells (hUCMSCs) to restore ovarian function in rats with premature ovarian failure...

2022-06-27