【Animal Modeling】-A new lethal virus model

The Middle East Respiratory Syndrome Coronavirus is a new type of highly pathogenic coronavirus that has emerged in recent years....

2022-02-12

【Animal Modeling】-How to establish a lung cancer brain metastasis model in nude mice?

Using Lanthanum Nitrate Tracer Electron Microscope to Observe the Ultrastructure of the Blood Brain Barrier in Nude Mice with Lung Cancer Brain Metastasis...

2022-02-12

【Animal Modeling】-Animal study on two different types of left atrial appendage occluder

To evaluate the feasibility and safety of occlusion of the left atrial appendage in animals with two different left atrial appendage occluders, the single-disc cylindrical type and the double-disc split type...

2022-02-12

【Animal Modeling】-The effect of human umbilical cord mesenchymal stem cells on the level of autophagy in the hippocampus of natural aging rats

To investigate whether transplantation of human umbilical cord mesenchymal stem cells can improve learning and memory and cognitive decline by regulating the level of autophagy in naturally aging rats...

2022-02-12

【Animal Modeling】-Protective effect and mechanism of estrogen on oxidative stress injury of mouse osteoblast MC3T3-E1

To investigate the protective effect and mechanism of estrogen on mouse osteoblast MC3T3-E1 oxidative stress injury...

2022-02-12

【Animal Model】-Interventional effect of valsartan on the activity of rat glomerular mesangial cells induced by high glucose

To investigate the effect and mechanism of valsartan on the proliferation and apoptosis of rat renal cells induced by high glucose...

2022-02-12

【Animal Modeling】-Effects of electroacupuncture on synaptic plasticity and microglia polarization in rats with cerebral ischemia

To explore synaptic plasticity and microglial polarization in rats with focal cerebral ischemia by electroacupuncture, and to detect the expression of miR-21/signal transducer and activator of transcription 3 (STAT3) pathway...

2022-02-12

【Animal Modeling】-Effect of ubiquitin carboxyl-terminal hydrolase 1 gene deletion on the reproductive system development of female mice

To study the effect of ubiquitin carboxyl-terminal hydrolase L1 gene deletion on the reproductive system of female mice...

2022-02-11

【Animal Modeling】-Systematic evaluation of the effects of placental differentially expressed proteins on the growth and development of placenta in a rat model of gestational diabetes mellitus

To systematically evaluate the effect of placental differentially expressed proteins on the growth and development of placenta in a rat model of gestational diabetes mellitus...

2022-02-11

【Animal modeling】-Effect and mechanism of Shenqu Xiaoshi oral liquid on gastrointestinal motility in mice with functional dyspepsia

To explore the effect and mechanism of Shenqu Xiaoshi Oral Liquid on gastrointestinal motility in functional dyspepsia (FD) mice...

2022-02-11

【Animal modeling】-The effect of paeoniflorin on Bayk8644-induced depression-anxiety-like behavior in rats and its mechanism

To investigate the pharmacological mechanism of paeoniflorin in improving depression-anxiety-like behavior in rats based on L-type voltage-dependent calcium channel...

2022-02-11

【Animal Model】-Effect of α-mangostin on the immune function of immunosuppressed mice

To investigate the effect of α-mangostin on the immune function of cyclophosphamide-induced immunosuppression in mice, and to provide experimental basis for the follow-up mechanism research and the development of new drugs to increase immune function...

2022-02-11

To investigate the therapeutic effect of rapamycin on 3,5-diethoxycarbonyl 1,4-dihydrocollidine (DDC)-induced mouse primary sclerosing cholangitis (PSC), and to explore its potential mechanism

To investigate the therapeutic effect of rapamycin on 3,5-diethoxycarbonyl 1,4-dihydrocollidine (DDC)-induced mouse primary sclerosing cholangitis (PSC), and to explore its potential mechanism...

2022-02-11

【Animal modeling】-Protective effect of curcumin on acute kidney injury in pregnant hypertensive rats

To investigate the protective effect of curcumin on acute kidney injury in rats caused by gestational hypertension and to explore its potential mechanism...

2022-02-11

【Animal Modeling】-Chronic toxicity test of Deinococcus radiodurans R1 in rats

To observe the chronic toxicity of Deinococcus radiodurans R1 to SD rats...

2022-02-10

【Animal modeling】-Protective effect of Xiaoxianxiong decoction on vascular endothelium in hyperlipidemic mice

To investigate the effect of Xiaoxianxiong Decoction on vascular endothelial injury in hyperlipidemia mice...

2022-02-10