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【Animal Modeling】-Miniature Pig Parotid Gland Atrophy Model

【Animal Modeling】-Miniature Pig Parotid Gland Atrophy Model

Due to the effects of radiotherapy on head and neck tumors, Sjogren’s syndrome and sialitis, the human’s major salivary glands experience gland atrophy and saliva reduction, which seriously affects the patient’s physiology and psychology...

2022-02-19
Cochlear implants have been upgraded due to gene therapy

Cochlear implants have been upgraded due to gene therapy

Researchers at the University of New South Wales School of Medicine in Australia use a gene therapy called electrical gene delivery, which uses electric fields to limit gene delivery near cochlear electrodes...

2022-02-19
【Animal Modeling】-Effect of Metformin on Learning and Memory Ability in Mice Aging

【Animal Modeling】-Effect of Metformin on Learning and Memory Ability in Mice Aging

To explore the effect and possible mechanism of metformin supplementation on the learning and memory ability of mice during the aging process of D-galactose-induced mice...

2022-02-18
【Animal modeling】-Effect of Tempol on NF-κB signaling pathway in myocardial hypertrophy rats

【Animal modeling】-Effect of Tempol on NF-κB signaling pathway in myocardial hypertrophy rats

To investigate the effect of 2, 2, 6, 6-tetramethyl-4-piperidinol (temPol) on NF-κB signaling pathway in rat cardiac hypertrophy?...

2022-02-18
【Animal modeling】-Analysis of the effect of portal hypertension on serum endotoxin and intestinal mucosa in rats

【Animal modeling】-Analysis of the effect of portal hypertension on serum endotoxin and intestinal mucosa in rats

To study the effect of simple portal hypertension on serum endotoxin and intestinal mucosa in rats?...

2022-02-18
【Animal Modeling】-Effect of Qingzao Jiufei Decoction and its decomposers on pulmonary inflammation-related factors in mice infected with Mycoplasma pneumoniae

【Animal Modeling】-Effect of Qingzao Jiufei Decoction and its decomposers on pulmonary inflammation-related factors in mice infected with Mycoplasma pneumoniae

To investigate the effect of Qingzao Jiufei Decoction (QJD) and its decomposers on the content of TNF-α?INF-γ in serum and the expression of MPN372?P1?AQP5 in lung tissue of mice infected with Mycoplasma pneumoniae (MP), and to clarify its anti-infla...

2022-02-18
【Animal Modeling】-Effect of high-fat diet feeding time on type 2 diabetic nephropathy rat model

【Animal Modeling】-Effect of high-fat diet feeding time on type 2 diabetic nephropathy rat model

To explore the effects of different high-fat diet feeding time on blood glucose, insulin resistance index (HOMA-IR) and urinary albumin excretion rate (UAER) in induced type 2 diabetic nephropathy (DN) rat model...

2022-02-18
【Animal modeling】-The effect of TRPV4 receptor on angiotensin II-induced renal damage in mice

【Animal modeling】-The effect of TRPV4 receptor on angiotensin II-induced renal damage in mice

To investigate the role of TRPV4 receptor in angiotensin II (Ang II)-induced renal damage by using transient receptor potential vanilloid isoform 4 knockout (TRPV4 - / - ) mice...

2022-02-18
【Animal Modeling】-Effect of Feilongzhi blood extract on inflammatory factors in hyperlipidemia rats with myocardial ischemia

【Animal Modeling】-Effect of Feilongzhi blood extract on inflammatory factors in hyperlipidemia rats with myocardial ischemia

To observe the effect of the blood extract of Feilongzhi on inflammatory factors in hyperlipidemia rats with myocardial ischemia, and to preliminarily explore the mechanism of TAE on cardiovascular protection...

2022-02-18
【Animal modeling】-Optimization of dose-response relationship between N-ethyl-N-nitrosourea and cyclophosphamide in pig-a gene mutation test in rats

【Animal modeling】-Optimization of dose-response relationship between N-ethyl-N-nitrosourea and cyclophosphamide in pig-a gene mutation test in rats

To study the effect of different doses of N-ethyl-N-nitrosourea (ENU) and cyclophosphamide (CP) on the deletion rate of ankyrin CD59 on the peripheral blood red blood cell surface of SD rats, and to optimize the Pig-a gene mutation test Detection met...

2022-02-18
【Animal modeling】-The protective effect and mechanism of glycyrrhizic acid on hippocampal neuron damage in epileptic rats

【Animal modeling】-The protective effect and mechanism of glycyrrhizic acid on hippocampal neuron damage in epileptic rats

To investigate the protective effect and related mechanism of glycyrrhizic acid on hippocampal neuron damage in epileptic rats...

2022-02-17
【Animal Modeling】- Nutrient Elements and Protein Combined Intervention of Fluorosis on Ovarian Function in Female Rats

【Animal Modeling】- Nutrient Elements and Protein Combined Intervention of Fluorosis on Ovarian Function in Female Rats

To investigate the changes of ovarian function in female mice by the combined intervention of calcium, magnesium, copper, zinc, vitamin D and protein on coal-burning fluorosis...

2022-02-17
【Animal modeling】-Effect of Xuanfei recipe on mTOR/S6K1 signaling pathway in endotoxin-induced acute lung injury in rats

【Animal modeling】-Effect of Xuanfei recipe on mTOR/S6K1 signaling pathway in endotoxin-induced acute lung injury in rats

To observe the effect of Xuanfei Decoction on the mTOR/S6K1 signaling pathway of endotoxin-induced acute lung injury in rats, and to explore its mechanism of action...

2022-02-17
【Animal Modeling】-Myocardial Fibrosis and Changes of Myocardial AGEs/RAGE Levels in Diabetic Rats

【Animal Modeling】-Myocardial Fibrosis and Changes of Myocardial AGEs/RAGE Levels in Diabetic Rats

To study the changes of myocardial fibrosis and myocardial AGEs/RAGE levels by constructing a type Ⅱ diabetic rat model...

2022-02-17
【Animal modeling】-Study on the effect of compound Ejiao paste on the endometrium of mice

【Animal modeling】-Study on the effect of compound Ejiao paste on the endometrium of mice

To investigate the effect of Compound Ejiao paste on the endometrium of mice...

2022-02-17
【Animal modeling】-Effect of curcumin pretreatment on myocardial oxidative stress and apoptosis in rats with heat stroke in dry heat environment

【Animal modeling】-Effect of curcumin pretreatment on myocardial oxidative stress and apoptosis in rats with heat stroke in dry heat environment

To observe the effects of curcumin pretreatment on myocardial oxidative stress and apoptosis in rats with heat stroke in a dry heat environment and explore its possible mechanism...

2022-02-16