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【Animal modeling】-Foxo3a gene regulates the development of rat ovarian granulosa cells in vitro and prevents the toxic effect of cisplatin on the ovary

【Animal modeling】-Foxo3a gene regulates the development of rat ovarian granulosa cells in vitro and prevents the toxic effect of cisplatin on the ovary

To study the regulation of Foxo3a gene on the development of rat ovarian granulosa cells in vitro and its preventive effect on the ovarian toxicity of cisplatin...

2022-02-25
【Animal Modeling】-Effect of Maca Extract on Toxicity and Immune Organs of Mice

【Animal Modeling】-Effect of Maca Extract on Toxicity and Immune Organs of Mice

To investigate the effects of maca extract on the toxicity and immune organs of mice...

2022-02-25
【Animal modeling】-Effect of tacrolimus on the expression of rat liver tissue protein phosphatase 2A and P-AKT

【Animal modeling】-Effect of tacrolimus on the expression of rat liver tissue protein phosphatase 2A and P-AKT

By observing the effects of tacrolimus on blood glucose, insulin levels, hepatic tissue protein phosphatase 2A and phosphorylated AKT expression in rats, to further explore the mechanism of tacrolimus-induced blood glucose elevation...

2022-02-25
【Animal Modeling】-Effect and mechanism of propofol intervention on optic nerve injury in rats

【Animal Modeling】-Effect and mechanism of propofol intervention on optic nerve injury in rats

To investigate the effect and mechanism of propofol intervention on the injured optic nerve and retinal ganglia after optic nerve injury in rats...

2022-02-25
【Animal modeling】-Effect of miR-126 on myocardial cell apoptosis in rats with acute myocardial infarction

【Animal modeling】-Effect of miR-126 on myocardial cell apoptosis in rats with acute myocardial infarction

To investigate the effect of miR-126 on myocardial cell apoptosis in acute myocardial infarction (AMI) rats...

2022-02-25
【Animal Modeling】-Comparison of the effect of gene therapy and traditional non-surgical therapy on postpartum stress urinary incontinence model rats

【Animal Modeling】-Comparison of the effect of gene therapy and traditional non-surgical therapy on postpartum stress urinary incontinence model rats

To study the effect of TGF-β1 gene therapy on rat model of postpartum stress urinary incontinence, and to explore the ideal new non-surgical treatment method for the disease...

2022-02-25
【Animal Modeling】-SOD activity of diabetic rats and the effect of antioxidant treatment on the antioxidant status of the body

【Animal Modeling】-SOD activity of diabetic rats and the effect of antioxidant treatment on the antioxidant status of the body

To explore the changes of SOD activity and protein expression in main organs of diabetic rats, and to observe the effect of the antioxidant N-acetylcysteine (NAC) on the antioxidant status of the body after short-term treatment (4 weeks)...

2022-02-25
【Animal Modeling】-Effect of Trichinella spiralis and its worm-derived protein on cecal ligation and puncture-induced sepsis in mice

【Animal Modeling】-Effect of Trichinella spiralis and its worm-derived protein on cecal ligation and puncture-induced sepsis in mice

To observe the effect of Trichinella spiralis and its parasite-derived protein on cecal ligation and puncture (CLP)-induced sepsis in mice...

2022-02-25
【Animal modeling】-Protective effect of liraglutide on stress-stressed chronic heart failure in rats

【Animal modeling】-Protective effect of liraglutide on stress-stressed chronic heart failure in rats

To study the effect and mechanism of liraglutide on cardiac function in pressure-stressed chronic heart failure rats...

2022-02-25
【Animal Model】-Diabetic Retinopathy Model

【Animal Model】-Diabetic Retinopathy Model

NOD xiǎo shǔ shì yánjiū rénlèi 1 xíng tángniàobìng zuì hǎo de móxíng, qí zài yíchuán hé miǎnyì fāngmiàn yǔ rénlèi jíqí xiāngsì 37/5000 NOD mice are the best model for studying human type 1 diabetes, which is very similar to humans in terms of genet...

2022-02-24
【Animal model】-Preparation of metabolic cataract model

【Animal model】-Preparation of metabolic cataract model

This type of cataract model uses various drugs to affect the metabolism of the lens to form cataracts. Commonly used are D-galactose, sodium selenate, naphthalene, glucocorticoids, and the less commonly used bleomycin, pinyangmycin and baiyao. , Cyst...

2022-02-24
【Animal Model】-Bacterial Keratitis Model

【Animal Model】-Bacterial Keratitis Model

The corneal stroma occupies 90% of the thickness of the cornea. It is composed of 100 to 200 layers of regularly arranged collagen fibers with a small amount of endogenous corneal cells between the corneal laminar fibers...

2022-02-24
【Animal Modeling】-Preparation method of genetically modified leukemia

【Animal Modeling】-Preparation method of genetically modified leukemia

bcr/abl transgenic mouse model: Cloning and analysis of the sequence and function of the mouse Tec gene promoter show that the genes controlled by the Tec promoter are only specifically expressed in the cytoplasm of hematopoietic stem cells...

2022-02-24
【Animal model】-Intubation injury rabbit aorta to form thrombus

【Animal model】-Intubation injury rabbit aorta to form thrombus

Copy method Experimental rabbits were fixed after anesthesia. Take a polyethylene tube (0.5 to 0.7 mm in diameter) and insert it into the aorta through the right femoral artery. After 4 hours, insert another polyethylene tube into the left carotid ar...

2022-02-24
[Animal Modeling]-Rat model of severe trauma and hemorrhagic shock

[Animal Modeling]-Rat model of severe trauma and hemorrhagic shock

Establish an improved rat model of severe traumatic shock and explore the protective effect of anesthesia on STHS rat model...

2022-02-24
【Animal Modeling】-Effects of chronic arsenic exposure on brain and serum metabolomics in mice

【Animal Modeling】-Effects of chronic arsenic exposure on brain and serum metabolomics in mice

To observe the effects of chronic arsenic exposure on the metabolomics of mouse cortex and serum, and to explore its neurotoxicity mechanism...

2022-02-23