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【Animal Modeling】-Metabolic rate determines primate brain development and lifespan

【Animal Modeling】-Metabolic rate determines primate brain development and lifespan

Researchers at Loyola University Chicago, co-authors of the groundbreaking study, found that humans have a higher metabolic rate than closely related primates, allowing humans to evolve to be larger brain...

2022-03-01
【Animal Modeling】-Aniline-induced DNA damage in mouse hepatocytes and lymphocytes and its repair effect

【Animal Modeling】-Aniline-induced DNA damage in mouse hepatocytes and lymphocytes and its repair effect

To study the genotoxicity of aniline and its repair kinetics...

2022-03-01
【Animal modeling】-Effect of octachlorodibenzodioxin on gene expression profile of mouse testis tissue

【Animal modeling】-Effect of octachlorodibenzodioxin on gene expression profile of mouse testis tissue

To investigate the effect of octachlorodibenzodioxins on the changes of gene expression profiles in the testis of male mice...

2022-03-01
【Animal modeling】-The protective effect of Zhenwu decoction on the heart of mice with uremic cardiomyopathy induced by most nephrectomy

【Animal modeling】-The protective effect of Zhenwu decoction on the heart of mice with uremic cardiomyopathy induced by most nephrectomy

To investigate the cardioprotective effect and mechanism of Zhenwu Decoction on uremic cardiomyopathy in mice...

2022-03-01
【Animal Modeling】-Effects of Four Commonly Used Experimental Anesthetics on Cardiovascular System of Rats

【Animal Modeling】-Effects of Four Commonly Used Experimental Anesthetics on Cardiovascular System of Rats

To investigate the effects of different animal experimental anesthetics on the cardiovascular system of rats...

2022-03-01
【Animal modeling】-Losartan reduces ventilator-related lung injury in mice and inhibits the expression of caveolin-1 and NOX4 in lung tissue

【Animal modeling】-Losartan reduces ventilator-related lung injury in mice and inhibits the expression of caveolin-1 and NOX4 in lung tissue

To establish a mouse model of mechanical lung injury by ventilator hyperventilation, intervene with angiotensin II receptor inhibitor losartan, and explore the effect of losartan on caveolin-1 in the lung of mice with mechanically ventilated lung inj...

2022-03-01
【Animal modeling】-nicotine inhibits MIA-induced apoptosis of rat osteoarthritis chondrocytes

【Animal modeling】-nicotine inhibits MIA-induced apoptosis of rat osteoarthritis chondrocytes

To investigate the inhibition of nicotine on the apoptosis of osteoarthritis chondrocytes induced by sodium iodoacetate (MIA)...

2022-02-28
【Animal modeling】-Construction and effect evaluation of Noggin gene silencing expression vector

【Animal modeling】-Construction and effect evaluation of Noggin gene silencing expression vector

To construct lentivirus-mediated Noggin RNAi interference sequences, and to analyze the silencing effect of these interference sequences on Noggin gene...

2022-02-28
【Animal Modeling】-Effect of triptolide on the expression of Notch pathway receptors and ligand genes in rats with adjuvant arthritis pulmonary function

【Animal Modeling】-Effect of triptolide on the expression of Notch pathway receptors and ligand genes in rats with adjuvant arthritis pulmonary function

To observe the effect of triptolide (TPT) on the expression of Notch receptor and ligand in adjuvant arthritis (AA) rats...

2022-02-28
【Animal modeling】-Estrogen reduces microvascular injury induced by chronic hypoperfusion in rat brain by up-regulating VEGF expression

【Animal modeling】-Estrogen reduces microvascular injury induced by chronic hypoperfusion in rat brain by up-regulating VEGF expression

By detecting the pathological changes of cerebral microvessels in different periods after permanent ligation of bilateral common carotid arteries (BCCAO) in rats and the effect of physiological dose of 17-β-estradiol (E2) replacement therapy, to expl...

2022-02-28
【Animal modeling】-Effect of dexmedetomidine pretreatment on inflammatory factors and oxidative stress in rats with septic kidney injury

【Animal modeling】-Effect of dexmedetomidine pretreatment on inflammatory factors and oxidative stress in rats with septic kidney injury

To investigate the effect of dexmedetomidine on inflammatory factors and oxidative stress of AKI (acute kidney injury) in septic rats...

2022-02-28
【Animal modeling】-New polycitric acid filler material induces soft tissue regeneration after rat skull defect

【Animal modeling】-New polycitric acid filler material induces soft tissue regeneration after rat skull defect

To evaluate the ability of two novel polycitric acid degradable biomaterials to induce soft tissue regeneration after calvarial defect in rats...

2022-02-28
【Animal Modeling】-Experimental study of CD45 mAb-mediated 188Re-avidin two-step pretargeting targeting lymphoma

【Animal Modeling】-Experimental study of CD45 mAb-mediated 188Re-avidin two-step pretargeting targeting lymphoma

To establish a CD45 mAb-mediated two-step pre-localization method for 188Re-avidin, observe its biological distribution in tumor-bearing mice, and evaluate its feasibility in the treatment of lymphoma...

2022-02-28
【Animal Modeling】-Research on the antidepressant mechanism of licorice and its application in animal behavior

【Animal Modeling】-Research on the antidepressant mechanism of licorice and its application in animal behavior

Depression, also known as \"emotional cold\", is a common affective disorder characterized by persistent low mood...

2022-02-28
【Animal modeling】-Protective effect of myricetin on ischemia-reperfusion injury in isolated rat hearts

【Animal modeling】-Protective effect of myricetin on ischemia-reperfusion injury in isolated rat hearts

To study the protective effect and mechanism of myricetin on ischemia-reperfusion injury in isolated rat hearts...

2022-02-28
【Animal Modeling】-Effect of subchronic exposure to diflubenzuron on the blood system of rats

【Animal Modeling】-Effect of subchronic exposure to diflubenzuron on the blood system of rats

Based on the study of the subchronic oral toxicity of diflubenzuron to rats, the effect on the blood system of rats after exposure was preliminarily discussed...

2022-02-28