【Animal modeling】-Effect of IGF-1 gene and electrical stimulation therapy on rat model of postpartum stress urinary incontinence

To study the effect of IGF-1 gene therapy on the rat model of postpartum stress urinary incontinence, and to explore the ideal treatment method for the disease...

2022-03-03

【Animal Modeling】-Effect of repetitive hypoxic preconditioning on liver injury induced by renal ischemia-reperfusion in rats

To investigate the effect of repetitive hypoxic preconditioning (RHP) on liver injury induced by renal ischemia-reperfusion injury (IRI) in rats and to preliminarily explore its mechanism...

2022-03-03

【Animal Modeling】-Regulatory T cell therapy for experimental mouse polymyositis and its mechanism

To investigate the therapeutic value and mechanism of CD4+ CD25+ Foxp3+ Treg cells in experimental autoimmune myositis (EAM) mice...

2022-03-03

【Animal Modeling】-Regulatory T cell therapy for experimental mouse polymyositis and its mechanism

To investigate the therapeutic value and mechanism of CD4+ CD25+ Foxp3+ Treg cells in experimental autoimmune myositis (EAM) mice...

2022-03-02

【Animal modeling】- Oral human alpha interferon transforms Bifidobacterium to promote the proliferation and maturation of mouse lymphocytes

To investigate the regulatory effect of human alpha interferon (IFN-α) gene on the immune function of mice after oral administration of Bifidobacterium transformed...

2022-03-02

【Animal modeling】-Pathological changes of amyloidosis and cerebrovascular disease in Alzheimer's disease rats

To investigate the pathological changes of brain tissue of amyloidosis cerebrovascular lesions on the basis of establishing an experimental rat model of Alzheimer\'s disease...

2022-03-02

【Animal modeling】-Recombinant lentivirus-mediated LXRα RNA interference improves the function of rat fatty liver donor liver transplantation

To investigate the effect and mechanism of LXRα RNA interference (RNAi) in improving liver function in rats with fatty liver after liver transplantation...

2022-03-02

【Animal modeling】-Effect of acute incision pain on the expression of connexin Cx43 in the dorsal horn of spinal cord in rats

To observe the effect of acute incision pain on the expression of connexin43 in the dorsal horn of rat spinal cord...

2022-03-02

【Animal Modeling】-Effect of Dexamethasone Pollution in Drinking Water on Intestinal Microflora in Mice

To investigate the effect of dexamethasone pollution in water environment on intestinal flora of mice...

2022-03-02

【Animal Modeling】-Changes of telemetry EEG activity in the sublimbic region of morphine-dependent rats during drug-seeking extinction

To investigate the effect of telemetry EEG activity in the sublimbic region on drug-seeking behavior in morphine-dependent rats during drug-seeking regression and its mechanism...

2022-03-01

【Animal Modeling】-Experimental Study on Changes of Platelet Mitochondria after Tourniquet Limb Ischemia-Reperfusion Injury in Rats

To investigate the changes of platelet mitochondria after tourniquet ischemia-reperfusion injury, and to provide guidance for the clinical application of tourniquet...

2022-03-01

【Animal modeling】-RNA interference specifically blocks the effect of local angiotensin II type 1 receptor on the first-phase insulin secretion in pancreatic islets

To observe the changes of insulin secretion in the first phase of pancreatic islets in db/db mice after blocking the expression of local angiotensin II type 1 receptor (AT1R) by RNA interference technology, and to explore its potential mechanism...

2022-03-01

【Animal modeling】-Protective effect of piperphentonamine hydrochloride on gentamicin-induced hearing loss in guinea pigs

To observe the relationship between guinea pig cochlear autophagy-related proteins beclin1 and LC3, Na+-K+-2Cl- co-transporter (NKCC1) mRNA, endothelin (ET) expression and cochlear gentamicin (GM) injury and piperphentonamine hydrochloride (PPTA) pro...

2022-03-01

【Animal modeling】-Protective effect of Apelin-13 on focal cerebral ischemia-reperfusion injury in rats

To investigate the protective effect of Apelin-13 on focal cerebral ischemia-reperfusion injury (CIRI) in rats and its possible mechanism...

2022-03-01

【Animal modeling】-Effect of thalidomide on bisphosphonate-related osteonecrosis of the jaw

To study the effect of thalidomide on bisphosphonate-related osteonecrosis of the jaw...

2022-03-01

【Animal Modeling】-Effects of hesperidin on antioxidant activity and gene expression of antioxidant enzymes in mice

To investigate the effect of hesperidin on the antioxidant effect of the body...

2022-03-01