内页大图
【Animal Modeling】-Isolation and Culture of Primary Tree Shrews Corneal Stromal Cells

【Animal Modeling】-Isolation and Culture of Primary Tree Shrews Corneal Stromal Cells

To explore a simple and easy method for rapid isolation and culture of tree shrew corneal stromal cells in vitro...

2022-03-09
【Animal modeling】-CRISPR/Cas9 system-mediated reproduction and identification of Slc6a6 knockout rats

【Animal modeling】-CRISPR/Cas9 system-mediated reproduction and identification of Slc6a6 knockout rats

To construct a taurine transporter knockout rat by CRISPR/Cas9 technology, breed and identify it, and provide a stable rat model for studying the effect of taurine deficiency on nervous system diseases...

2022-03-09
【Animal Modeling】-Based on the luciferase dual reporter gene system to verify in vitro that the Cip4 gene of gerbils is regulated by RXR and T4

【Animal Modeling】-Based on the luciferase dual reporter gene system to verify in vitro that the Cip4 gene of gerbils is regulated by RXR and T4

To investigate the regulatory effects of nuclear transcription factors TRB, RXR and agonist T4 on Cip4 gene expression in gerbils...

2022-03-09
【Animal Modeling】-Application of Heat Pipe Air Heat Exchanger in the Construction of Laboratory Animal Facilities

【Animal Modeling】-Application of Heat Pipe Air Heat Exchanger in the Construction of Laboratory Animal Facilities

To use the heat pipe air heat exchanger to exchange heat with the gas discharged from the laboratory animal facility, recover the temperature energy in the exhaust gas, and use the recovered energy in the fresh air to reduce the energy consumption of...

2022-03-08
【Animal modeling】-D-galactose increases the expression of IL-18 in the gut of tree shrew and the intestinal flora imbalance

【Animal modeling】-D-galactose increases the expression of IL-18 in the gut of tree shrew and the intestinal flora imbalance

To analyze the expression of IL-18 in the intestinal tissue of tree shrew and the changes of intestinal flora under the action of D-galactose...

2022-03-08
【Animal modeling】-Analysis of peripheral blood and immune cell typing of aged and young SD rats

【Animal modeling】-Analysis of peripheral blood and immune cell typing of aged and young SD rats

To compare the differences of peripheral blood and immune cell typing indexes between aged SD rats and young SD rats...

2022-03-08
【Animal modeling】-The killing effect of PBLC of guinea pigs with different FMDV susceptibility on simulated FMDV-infected cells

【Animal modeling】-The killing effect of PBLC of guinea pigs with different FMDV susceptibility on simulated FMDV-infected cells

To investigate the genetic and immunological mechanisms of guinea pigs resistance to foot-and-mouth disease virus (FMDV). To elucidate the feasibility of FMDV pseudovirus-infected cells for studying FMDV pathogenesis...

2022-03-08
【Animal modeling】-Comparative study on the microbial composition of different parts of the digestive tract of wild tree shrew and artificially reared tree shrew

【Animal modeling】-Comparative study on the microbial composition of different parts of the digestive tract of wild tree shrew and artificially reared tree shrew

Using tree shrew as a research model to explore the composition of microbiota in different intestinal segments of wild tree shrew and artificially bred tree shrew...

2022-03-08
【Animal modeling】-Screening CA16 pathogenic related genes using genetically diverse mouse resources

【Animal modeling】-Screening CA16 pathogenic related genes using genetically diverse mouse resources

Coxsackievirus A16 is one of the main pathogenic pathogens of hand, foot and mouth disease, and its pathogenic mechanism is not yet clear....

2022-03-08
【Animal modeling】-Establishment and validation of electroporation transfection conditions for mouse macrophage RAW264.7 cells

【Animal modeling】-Establishment and validation of electroporation transfection conditions for mouse macrophage RAW264.7 cells

To screen and verify the conditions of electroporation for transfection of TRIB3 overexpression plasmid and TRIB3 siRNA in RAW264.7 cells, and to establish the optimal electroporation transfection scheme for RAW264.7 cells...

2022-03-08
【Animal modeling】-α-synuclein A53T mutation impairs cognitive function in mice

【Animal modeling】-α-synuclein A53T mutation impairs cognitive function in mice

To explore the changes of cognitive function, motor function, anxiety-like behavior and pathological changes in α-synuclein A53T transgenic mice...

2022-03-08
【Animal modeling】-Isolation, identification and drug sensitivity test of Proteus mirabilis from cynomolgus monkeys

【Animal modeling】-Isolation, identification and drug sensitivity test of Proteus mirabilis from cynomolgus monkeys

To provide theoretical and technical support for microbial detection of imported experimental monkeys and how to carry out feeding management and disease prevention and control by identifying and drug susceptibility testing of Proteus mirabilis isola...

2022-03-08
【Animal Modeling】-Construction of Bpi Gene Knockout Mice Using CRISPR/Cas9 Technology

【Animal Modeling】-Construction of Bpi Gene Knockout Mice Using CRISPR/Cas9 Technology

To use CRISPR/Cas9 gene editing technology to efficiently construct Bpi gene knockout mouse model, and to continue to breed, identify and build stable genetic Bpi gene knockout mouse strains...

2022-03-08
【Animal modeling】-Establishment of standard biological indicators of SD rats in GLP barrier environment animal laboratory

【Animal modeling】-Establishment of standard biological indicators of SD rats in GLP barrier environment animal laboratory

To establish the biological indicators of normal SD rats in the long-term toxicity test in the barrier environment animal laboratory of the Chinese Medicine Safety Evaluation Center (CLP), and to provide reference indicators for future researchers...

2022-03-08
【Animal Modeling】- Histopathological study of skin healing in miniature pigs after deep second-degree burns

【Animal Modeling】- Histopathological study of skin healing in miniature pigs after deep second-degree burns

To establish a pig model of deep second-degree scald, and to observe the histopathological changes of skin repaired at different time points...

2022-03-08
【Animal Modeling】- Transcriptome Analysis of Human Cells Infected by Porcine Circovirus Type 2

【Animal Modeling】- Transcriptome Analysis of Human Cells Infected by Porcine Circovirus Type 2

Whether circovirus 2 can infect human cells has been a topic of debate...

2022-03-08