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【Animal modeling】-Preparation of rat thoracic aortic vascular smooth muscle cells by an improved two-step compound enzyme digestion method

【Animal modeling】-Preparation of rat thoracic aortic vascular smooth muscle cells by an improved two-step compound enzyme digestion method

This paper reports an improved method for the isolation of rat thoracic aortic vascular smooth muscle cells based on compound enzymatic digestion...

2022-02-21
【Animal Modeling】-Discussion on the mode of administration of cyclophosphamide in rabbit embryo-fetal developmental toxicity test

【Animal Modeling】-Discussion on the mode of administration of cyclophosphamide in rabbit embryo-fetal developmental toxicity test

To investigate the effects of different administration routes and doses of cyclophosphamide on the embryos and fetuses of pregnant rabbits, so as to determine the best administration method for inducing fetal malformation in rabbits...

2022-02-21
【Animal modeling】-Protective effect of GDF11 on myocardial injury in type II diabetic mice

【Animal modeling】-Protective effect of GDF11 on myocardial injury in type II diabetic mice

To observe the protective effect of GDF11 on myocardial injury and the changes of myocardial apoptosis in C57BL/6J mice with type Ⅱ diabetes...

2022-02-21
【Animal Modeling】-The effect of exercise on pancreatic islets in diabetic rats and its mechanism

【Animal Modeling】-The effect of exercise on pancreatic islets in diabetic rats and its mechanism

To investigate the effect of aerobic exercise on pancreatic islets and β cells in type 2 diabetic rats and its mechanism...

2022-02-21
【Animal modeling】The effect of -1α,25(OH)2D3 on the expression of lubricin in rat articular chondrocytes

【Animal modeling】The effect of -1α,25(OH)2D3 on the expression of lubricin in rat articular chondrocytes

To investigate the effect of 1α,25(OH)2D3 on the synthesis and secretion of lubricin in chondrocytes at the cellular level...

2022-02-21
【Animal modeling】-Flow cytometry analysis of the phenotypic characteristics of PMA-induced THP-1 differentiation into macrophages

【Animal modeling】-Flow cytometry analysis of the phenotypic characteristics of PMA-induced THP-1 differentiation into macrophages

To clarify the differentiation of macrophages derived from THP-1 cells induced by PMA alone by flow cytometry...

2022-02-21
【Animal modeling】-The effect of platelet-rich plasma on rabbit Achilles tendon healing

【Animal modeling】-The effect of platelet-rich plasma on rabbit Achilles tendon healing

Surgical treatment of acute Achilles tendon rupture includes early accelerated rehabilitation, which shortens the fixation period and allows early range exercise and muscle strengthening exercises...

2022-02-19
【Animal Modeling】-The effect of methylene blue and sevoflurane on serum and lung tissue oxidative stress indicators and inflammatory factors in a rat model of lung ischemia-reperfusion (IR) injury

【Animal Modeling】-The effect of methylene blue and sevoflurane on serum and lung tissue oxidative stress indicators and inflammatory factors in a rat model of lung ischemia-reperfusion (IR) injury

To study the effects of methylene blue and sevoflurane on oxidative stress indicators and inflammatory factors in serum and lung tissue of rats with lung ischemia-reperfusion (IR) injury...

2022-02-19
[Animal Modeling]-Epileptic mouse model of primary epilepsy

[Animal Modeling]-Epileptic mouse model of primary epilepsy

The replication method is to measure the degree of epileptic seizures of the mice before the experiment and select suitable experimental animals...

2022-02-19
【Animal Modeling】-L-glutamic acid induces neonatal rat-dependent retinal toxicity

【Animal Modeling】-L-glutamic acid induces neonatal rat-dependent retinal toxicity

Glutamate, an excitatory neurotransmitter in the retina, is known to cause excitotoxicity, in which neuronal cell death occurs after excessive excitatory neurotransmitter....

2022-02-19
【Animal Modeling】-Yucatan mini-pig congenital ventricular septal defect model

【Animal Modeling】-Yucatan mini-pig congenital ventricular septal defect model

In infants born in humans, the incidence of congenital ventricular septal defect (VSD) is about 0.1% to 0.2%, making it one of the most common congenital malformations....

2022-02-19
【Animal Modeling】-Efficacy observation and action path of Eucommia ulmoides extract on mice with lipopolysaccharide-induced mastitis

【Animal Modeling】-Efficacy observation and action path of Eucommia ulmoides extract on mice with lipopolysaccharide-induced mastitis

How to study the therapeutic effect and behavior of eucommia extract on mice with mastitis?...

2022-02-19
【Animal Modeling】-A model of myocardial infarction caused by electrical stimulation of the canine coronary artery

【Animal Modeling】-A model of myocardial infarction caused by electrical stimulation of the canine coronary artery

Fix the animal in the correct position of the pressure ulcer and separate the femoral artery and vein. Using these, measure the peripheral arterial pressure, give a test sample, and give anesthesia [Add 500ml of normal saline to 10ml of 3% sodium pen...

2022-02-19
【Animal Modeling】-Establishment of rat models of acute and chronic tubal inflammatory infertility caused by Staphylococcus aureus

【Animal Modeling】-Establishment of rat models of acute and chronic tubal inflammatory infertility caused by Staphylococcus aureus

Objective: To establish a rat model of acute and chronic tubal inflammatory infertility with Staphylococcus aureus...

2022-02-19
【Animal Modeling】-Miniature Pig Root Resorption Model

【Animal Modeling】-Miniature Pig Root Resorption Model

Root resorption is a common and difficult complication in orthodontic treatment, and root resorption involves many factors, including age, sex, nutritional status, appliance type, orthodontic strength, correction method and treatment process...

2022-02-19
【Animal Modeling】-Vertical osteotomy of bilateral mandibular ramus in miniature pig

【Animal Modeling】-Vertical osteotomy of bilateral mandibular ramus in miniature pig

Orthognathic surgery and animal experiments of the temporomandibular joint use animal models to simulate various orthodontic operations on the human body and observe the postoperative morphological and functional changes of the temporomandibular join...

2022-02-19