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【Animal modeling】-Comparing the similarities and differences of oral flora between humans and commonly used experimental animals by 16S rRNA high-throughput sequencing

【Animal modeling】-Comparing the similarities and differences of oral flora between humans and commonly used experimental animals by 16S rRNA high-throughput sequencing

To use 16S rRNA high-throughput sequencing method to determine the oral flora of several commonly used experimental animals (Tibetan miniature pigs, beagle dogs, macaques, New Zealand rabbits, Wistar rats), and to compare and analyze the oral flora o...

2022-02-08
【Animal Modeling】-SOD activity of diabetic rats and the effect of antioxidant treatment on the antioxidant status of the body

【Animal Modeling】-SOD activity of diabetic rats and the effect of antioxidant treatment on the antioxidant status of the body

To explore the changes of SOD activity and protein expression in main organs of diabetic rats, and to observe the effect of the antioxidant N-acetylcysteine (NAC) on the antioxidant status of the body after short-term treatment (4 weeks)....

2022-02-08
【Animal Modeling】-Changes of Blood Indexes in Long-term Toxicity Experiment of Niaotongkake Naiqi Tablets in Rats

【Animal Modeling】-Changes of Blood Indexes in Long-term Toxicity Experiment of Niaotongkake Naiqi Tablets in Rats

To investigate the changes of hematological indexes in the long-term toxicity test of Niaotongkake Naiqi tablets in rats...

2022-02-08
【Animal Modeling】-The relationship between sex differences in blood pressure and sodium channels in mouse kidneys

【Animal Modeling】-The relationship between sex differences in blood pressure and sodium channels in mouse kidneys

To study blood pressure, renal urinary sodium excretion and related renal sodium channels and signaling pathways in male and female mice, and to preliminarily explore the relationship between sex differences in blood pressure and renal sodium channel...

2022-02-08
【Animal Modeling】-Multi-electrode array implantation on choroid

【Animal Modeling】-Multi-electrode array implantation on choroid

Retinitis pigmentosa (Rp) is a hereditary degenerative retinal disease, which causes specific loss of photoreceptors and retinal pigment epithelium (RPE), and is accompanied by severe visual impairment...

2022-02-06
【Animal Modeling】-Mice Acne Model

【Animal Modeling】-Mice Acne Model

Choosing suitable mouse acne models for different experimental purposes is very important for studying the pathogenesis of acne and evaluating the effectiveness of anti-acne drugs...

2022-02-06
【Animal Modeling】-The effect of intermittent fasting on the intestinal flora and metabolism of obese rats

【Animal Modeling】-The effect of intermittent fasting on the intestinal flora and metabolism of obese rats

To study the effects of intermittent fasting on metabolism and intestinal flora in elderly obese rats...

2022-02-06
【Animal Modeling】-Establishment of in vitro apoptosis model of rat intervertebral disc nucleus pulposus cells

【Animal Modeling】-Establishment of in vitro apoptosis model of rat intervertebral disc nucleus pulposus cells

Establishment of an in vitro apoptosis model of rat nucleus pulposus cells...

2022-02-06
【Animal Modeling】-The neuroprotective effect of artesunate on mice with experimental autoimmune encephalomyelitis and the effect of autophagy

【Animal Modeling】-The neuroprotective effect of artesunate on mice with experimental autoimmune encephalomyelitis and the effect of autophagy

How to study the neuroprotective and autophagy effects of artesunate on experimental autoimmune encephalomyelitis (EAE) mice?...

2022-02-06
【Animal Modeling】-The use of bionic intestinal chip to study the intestinal tissue damage induced by new coronavirus infection has made progress

【Animal Modeling】-The use of bionic intestinal chip to study the intestinal tissue damage induced by new coronavirus infection has made progress

  The new coronavirus (SARS-CoV-2) infection has caused a global pandemic, posing a major public health crisis, and seriously threatening human health...

2022-02-06
【Animal Modeling】-How to verify the animal model of glaucoma?

【Animal Modeling】-How to verify the animal model of glaucoma?

Glaucoma is a neurodegenerative disease whose pathological feature is the death of retinal ganglion cells (RGC)...

2022-02-06
【Animal Modeling】-How to establish a small pig model of chronic myocardial ischemia with the syndrome of phlegm and blood stasis?

【Animal Modeling】-How to establish a small pig model of chronic myocardial ischemia with the syndrome of phlegm and blood stasis?

Intravenous injection of vitamin D3 (VD3) and isoproterenol to establish a piglet model of high-fat chronic myocardial ischemia...

2022-02-06
【Animal Modeling】-Experiment on the effect of curcumin on the survival rate of rats in desert dry and hot environment

【Animal Modeling】-Experiment on the effect of curcumin on the survival rate of rats in desert dry and hot environment

To discuss the effect of curcumin on the survival rate of rats in the desert dry and hot environment...

2022-02-06
【Animal Modeling】-The effect of angiotensin (1-7) on the expression of GFAP, GDNF and cognitive function in the hippocampus of diabetic rats

【Animal Modeling】-The effect of angiotensin (1-7) on the expression of GFAP, GDNF and cognitive function in the hippocampus of diabetic rats

Observe the effects of angiotensin (1-7) [Ang(1-7)] on the expression of glial fibrillary acidic protein (GFAP), glial cell-derived neurotrophic factor (GDNF) and cognitive function in the diabetic hippocampus influences...

2022-02-06
【Animal Modeling】-Research progress on behavioral evaluation of animal models of spinal cord injury

【Animal Modeling】-Research progress on behavioral evaluation of animal models of spinal cord injury

Various SCl animal models such as spinal cord contusion, compression injury, transection injury, ischemic injury, stretch injury and chemical injury have been established at home and abroad, and pharmacodynamic screening of some neuroprotective drugs...

2022-02-06
【Animal Modeling】-Preliminary Study on the Effect of Lipopolysaccharide on Naked Mole Lung Tissue

【Animal Modeling】-Preliminary Study on the Effect of Lipopolysaccharide on Naked Mole Lung Tissue

To observe and analyze the effects of lipopolysaccharide (LPS) on the morphological structure and pathological indexes of naked mole rats\\\' lung tissues, and to preliminarily explore whether the naked mole rats are resistant to LPS...

2022-02-06