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【Animal Modeling】-Naphthoquine induces central nervous system and hepatic vascular center toxicity in Beagle dogs

【Animal Modeling】-Naphthoquine induces central nervous system and hepatic vascular center toxicity in Beagle dogs

He was approximately 14 months old at the start of the administration and weighed 7.8 to 10.1 kg. Vehicle control group (0 mg/kg/day, 1 female and 1 male), low-dose group (2 mg/kg/day, 1 female and 1 male) and medium-dose group (10 mg/kg/day, 1 femal...

2022-01-31
【Animal modeling】-Effect of low selenium diet on the expressions of CD163, CD206 and CCR7 in the liver and kidney of rats

【Animal modeling】-Effect of low selenium diet on the expressions of CD163, CD206 and CCR7 in the liver and kidney of rats

To investigate the effect of low selenium diet on liver and kidney in rats, and the role of macrophage polarization to M1 and M2 in liver and kidney fibrosis...

2022-01-28
【Animal Modeling】-Glucagon-like polypeptide-1 improves learning and memory ability in type 2 diabetic rats

【Animal Modeling】-Glucagon-like polypeptide-1 improves learning and memory ability in type 2 diabetic rats

To observe the improvement effect of diabetes treatment drug glucagon-like peptide-1 (GLP-1) on learning and memory dysfunction in diabetic rats...

2022-01-28
【Animal modeling】-Effect of hypoxic preconditioning on the formation of endometriotic lesions in rats

【Animal modeling】-Effect of hypoxic preconditioning on the formation of endometriotic lesions in rats

To understand the effect of hypoxic preconditioning on the formation of ectopic lesions in a rat model of endometriosis, so as to further clarify the molecular mechanism of the occurrence and development of EMs, so as to provide new ideas for its pre...

2022-01-28
【Animal Modeling】-Depression-like behavioral changes in male and female rats induced by restraint stress of different durations

【Animal Modeling】-Depression-like behavioral changes in male and female rats induced by restraint stress of different durations

To investigate the effects of chronic restraint stress of different restraint durations on the depression-like behavior of male and female SD rats, and to provide a basis for the selection of experimental animals\\\' gender and experimental duration ...

2022-01-28
【Animal modeling】-Effect of Bcl-2 inhibitor on astragalus injection on reducing the apoptosis of hippocampal neurons in rats with hypoxia and hypoglycemia/reoxygenation and reglycemia

【Animal modeling】-Effect of Bcl-2 inhibitor on astragalus injection on reducing the apoptosis of hippocampal neurons in rats with hypoxia and hypoglycemia/reoxygenation and reglycemia

To investigate the effect of astragalus injection (AI) on the apoptosis of hippocampal neurons in hypoxia-hypoglycemia/reoxygenation and reglycemia (H/R) rats under the action of Bcl-2 inhibitor (TW-37)...

2022-01-28
【Animal Modeling】-Study on the synergistic analgesic effect of choline and parecoxib sodium and its mechanism through mouse experiments

【Animal Modeling】-Study on the synergistic analgesic effect of choline and parecoxib sodium and its mechanism through mouse experiments

To investigate the interaction between choline and parecoxib sodium in analgesia and to conduct a preliminary study on its mechanism...

2022-01-28
【Animal modeling】-Experimental study on the differentiation of bone marrow mesenchymal stem cells into cardiomyocyte-like cells induced by Jiawei Danshen Decoction in vitro

【Animal modeling】-Experimental study on the differentiation of bone marrow mesenchymal stem cells into cardiomyocyte-like cells induced by Jiawei Danshen Decoction in vitro

Experimental study on the differentiation of bone marrow mesenchymal stem cells into cardiomyocyte-like cells induced by modified Danshen decoction in vitro...

2022-01-28
【Animal Modeling】-Effects of benzene pollution on liver and kidney function and blood nucleotide levels in rats

【Animal Modeling】-Effects of benzene pollution on liver and kidney function and blood nucleotide levels in rats

To explore the effect of benzene on liver and kidney function and blood nucleotide levels in Wistar rats...

2022-01-28
【Animal modeling】-Protective effect of ginseng coenzyme Q10 sunscreen on UV-injured mice

【Animal modeling】-Protective effect of ginseng coenzyme Q10 sunscreen on UV-injured mice

Study on the protective effect of ginseng coenzyme Q10 sunscreen on UV-injured mice...

2022-01-28
【Animal Modeling】-Preliminary study on the mechanism of hypoxic preconditioning reducing the susceptibility to epilepsy and its brain protective effect in rats

【Animal Modeling】-Preliminary study on the mechanism of hypoxic preconditioning reducing the susceptibility to epilepsy and its brain protective effect in rats

To preliminarily investigate the effect of intermittent hypoxic preconditioning on epileptic seizures in rats induced by lithium chloride and pilocarpine and its brain protective mechanism...

2022-01-28
【Animal Modeling】-A comparative study of two puncture routes for hepatic artery intubation in rabbits

【Animal Modeling】-A comparative study of two puncture routes for hepatic artery intubation in rabbits

To explore the route and method of hepatic artery cannulation in experimental rabbits...

2022-01-28
【Animal modeling】-Effect of Bushen Cuovv Decoction on ovarian morphology and sex hormones in polycystic ovary syndrome model rats

【Animal modeling】-Effect of Bushen Cuovv Decoction on ovarian morphology and sex hormones in polycystic ovary syndrome model rats

To explore the mechanism of Bushen Cuovv Decoction in the treatment of polycystic ovary syndrome by observing the effects of Bushen Cuovv Decoction on sex hormones, anti-Müllerian hormone and ovarian morphology in polycystic ovary syndrome model rats...

2022-01-28
【Animal modeling】-Distribution and differential expression of Hba-α protein in hatched blastocysts and dormant embryos of mice before and after programmed freezing

【Animal modeling】-Distribution and differential expression of Hba-α protein in hatched blastocysts and dormant embryos of mice before and after programmed freezing

To explore the distribution and differential expression of Hba-α protein in hatched blastocysts and dormant embryos of mice before and after freezing by means of programmed freezing, so as to provide a theoretical basis for the future development and...

2022-01-28
【Animal Modeling】-The effect of targeted inhibition of macrophage Act1 expression on ulcerative colitis

【Animal Modeling】-The effect of targeted inhibition of macrophage Act1 expression on ulcerative colitis

To investigate the role of macrophage NF-κB activating factor 1 in inflammatory bowel disease...

2022-01-28
What is the retinal aging model in mice caused by osteopontin deficiency? -【Animal Modeling】

What is the retinal aging model in mice caused by osteopontin deficiency? -【Animal Modeling】

Osteopontin (OPN) is a secreted glycosylated phosphoprotein encoded by the SPP1 gene...

2022-01-27