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【Animal Modeling】-Preliminary Study on the Effect of Lipopolysaccharide on Naked Mole Lung Tissue

【Animal Modeling】-Preliminary Study on the Effect of Lipopolysaccharide on Naked Mole Lung Tissue

To observe and analyze the effects of lipopolysaccharide on the morphological structure and pathological indexes of naked mole rats’ lung tissues, and to preliminarily explore whether the naked mole rats are resistant to LPS...

2022-02-01
【Animal Modeling】-Lentivirus-mediated shRNA targeting survivin gene inhibits the growth of endometrium in the abdominal cavity of nude mice

【Animal Modeling】-Lentivirus-mediated shRNA targeting survivin gene inhibits the growth of endometrium in the abdominal cavity of nude mice

To study the effect of lentivirus-mediated survivin gene specific short hairpin RNA (shRNA) on the growth of human endometrium implanted in the abdominal cavity of nude mice...

2022-02-01
【Animal Modeling】-What is the source tumor tissue xenograft model?

【Animal Modeling】-What is the source tumor tissue xenograft model?

The tumor transplantation model established by transplanting the patient\\\\\\\'s tumor tissue into immunodeficient mice retains the biological characteristics of the primary tumor, but the matrix components of the tumor tissue are passaged in the mi...

2022-02-01
【Animal Modeling】-Small Ubiquitin-like Modifier Protease 3 Regulates Autophagy in Mouse Alveolar Type Ⅱ Epithelial Cells

【Animal Modeling】-Small Ubiquitin-like Modifier Protease 3 Regulates Autophagy in Mouse Alveolar Type Ⅱ Epithelial Cells

To investigate the regulatory effect and molecular mechanism of small ubiquitin-like modifier-specific protease 3 on autophagy in mouse lung tissue cells...

2022-02-01
【Animal Modeling】-Ⅲ Type Allergic Reaction Model

【Animal Modeling】-Ⅲ Type Allergic Reaction Model

Replication method Dissolve rabbit anti-bovine serum albumin antiserum in PBS, pH 7.2, put 100μl into rabbit eyelid conjunctiva four times...

2022-02-01
【Animal Modeling】-How to establish an experimental animal model of chronic obstructive pulmonary disease?

【Animal Modeling】-How to establish an experimental animal model of chronic obstructive pulmonary disease?

Chronic obstructive pulmonary disease (COPD) is the leading cause of morbidity and mortality worldwide...

2022-01-31
【Animal Modeling】-How to improve the method of constructing myocardial ischemia-reperfusion injury model?

【Animal Modeling】-How to improve the method of constructing myocardial ischemia-reperfusion injury model?

Improved method for comprehensive evaluation of rat myocardial ischemia-reperfusion injury model...

2022-01-31
【Animal Modeling】-How to compare different animal models of Graves disease?

【Animal Modeling】-How to compare different animal models of Graves disease?

The purpose of this study is to start from the immune-related mechanisms of Graves disease, compare our previous studies of mouse and macaque GD animal models, explore the differences in the characteristics of different animal GD models, and based on...

2022-01-31
When will the first CRISPR/Cpf1 gene editing of rabbit and pig models be completed? -【Animal Modeling】

When will the first CRISPR/Cpf1 gene editing of rabbit and pig models be completed? -【Animal Modeling】

Lai Liangxue’s group from the Guangzhou Institute of Biomedical Sciences, Chinese Academy of Sciences published a new gene editing study in the international journal Cell and Molecular Life Sciences, \\\\\\\"Engineering CRISPR/Cpf1withtRNA to pr...

2022-01-31
【Animal Modeling】-How to build an animal model of human intestinal flora of Alzheimer\\

【Animal Modeling】-How to build an animal model of human intestinal flora of Alzheimer

Fecal bacterial transplantation was used to obtain human flora-related (HFA) model mouse Alzheimer\\\'s disease through oral route, and the model was evaluated through bioinformatics, histopathology and other methods...

2022-01-31
【Animal Modeling】-What is the difference between spontaneous and induced type 2 diabetes mouse models?

【Animal Modeling】-What is the difference between spontaneous and induced type 2 diabetes mouse models?

Compare the differences in glucose metabolism, insulin resistance and inflammation between spontaneous and induced type 2 diabetic mouse models...

2022-01-31
【Animal Modeling】-Single intraosseous injection of simvastatin promotes normalization of breast cancer tumor blood vessels in mice

【Animal Modeling】-Single intraosseous injection of simvastatin promotes normalization of breast cancer tumor blood vessels in mice

To study the effect of a single intraosseous injection of simvastatin on the vascular structure and function of breast cancer tumors in mice...

2022-01-31
【Animal Modeling】-Post-traumatic stress disorder model

【Animal Modeling】-Post-traumatic stress disorder model

Establish a model of post-traumatic stress disorder through single long-term stress (SPS), and observe the effect of orphan feeding on SPS model rats...

2022-01-31
【Animal Modeling】-How to build an animal model of choroidal and retinal neovascularization?

【Animal Modeling】-How to build an animal model of choroidal and retinal neovascularization?

The development of animal models of choroidal neovascularization (CNV) and retinal neovascularization (RNV) contributes to the understanding of biology in this situation...

2022-01-31
【Animal Modeling】-How to establish a Hr gene knockout mouse model?

【Animal Modeling】-How to establish a Hr gene knockout mouse model?

Establish knockout mice and study the function of hairless gene (Hr) in detail...

2022-01-31
【Animal Modeling】-Light Thrombus Stroke Model

【Animal Modeling】-Light Thrombus Stroke Model

Stroke has a high fatality rate, disability rate and recurrence rate, which is an insurmountable disease for human beings. It is mainly divided into hemorrhagic stroke and ischemic stroke. The latter accounts for 80% of all strokes...

2022-01-31