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【Animal Modeling】-Bupivacaine-induced Myocardial Cell Mitochondria Damage Rat Model

【Animal Modeling】-Bupivacaine-induced Myocardial Cell Mitochondria Damage Rat Model

Observe the changes in the mitochondrial morphology of bupivacaine cardiomyocytes and the production of reactive oxygen species under electrical stimulation, and explore the establishment of an ideal rat cardiomyocyte model of bupivacaine poisoning...

2022-02-01
【Animal Modeling】-The establishment of a mouse model of erlotinib-induced skin adverse reactions

【Animal Modeling】-The establishment of a mouse model of erlotinib-induced skin adverse reactions

Erlotinib is a new type of targeted drug for the treatment of non-small cell lung cancer. In recent years, it has been widely used in clinical practice, but it has many side effects. Among them, rash is the most common and most difficult for patients...

2022-02-01
[Animal Modeling]-Explore the effect of natural hot spring water on lipid peroxidation in aged mice

[Animal Modeling]-Explore the effect of natural hot spring water on lipid peroxidation in aged mice

To study the effectiveness and feasibility of vaccine immune intervention with human-derived RBP-4 as the target of insulin resistance, and to provide basic research data for advancing the development of new therapies for type 2 diabetes...

2022-02-01
The protective effect of anesthesia on the establishment of a rat model of severe trauma and hemorrhagic shock

The protective effect of anesthesia on the establishment of a rat model of severe trauma and hemorrhagic shock

Establish a modified rat model of severe trauma and hemorrhagic shock to explore the protective effect of anesthesia on the establishment of STHS rat model...

2022-02-01
【Animal Modeling】-Establishment and evaluation of rabbit knee osteoarthritis model

【Animal Modeling】-Establishment and evaluation of rabbit knee osteoarthritis model

Preparation and evaluation of rabbit knee osteoarthritis model by rabbit cartilage defect...

2022-02-01
【Animal Modeling】-How to establish a nude mouse model of human prostate cancer xenograft?

【Animal Modeling】-How to establish a nude mouse model of human prostate cancer xenograft?

Establish a human-derived xenograft (PDX) model of prostate cancer and evaluate the anti-tumor efficacy of various treatment options?...

2022-02-01
【Animal modeling】-Effects of bis(2-ethylhexyl) phthalate exposure during pregnancy on growth and development of mouse placenta

【Animal modeling】-Effects of bis(2-ethylhexyl) phthalate exposure during pregnancy on growth and development of mouse placenta

Through exposure to bis(2-ethylhexyl) phthalate (DEHP) during pregnancy, observe the effects of DEHP exposure on the growth and development of mouse placenta, the number of uNK cells at the maternal-fetal interface, and angiogenesis in vivo...

2022-02-01
【Animal Modeling】-Determination of Microbial Diversity of Common Cotton-eared Marmoset Manure Based on High-throughput Sequencing Technology

【Animal Modeling】-Determination of Microbial Diversity of Common Cotton-eared Marmoset Manure Based on High-throughput Sequencing Technology

Apply high-throughput sequencing technology to analyze the structure and composition of the fecal flora of common cotton-eared marmoset monkeys, and lay the foundation for the further development and utilization of new experimental animals...

2022-02-01
[Animal Modeling]-Hemorrhoids Magnetizing Ointment to Mouse Model of Hemorrhoids

[Animal Modeling]-Hemorrhoids Magnetizing Ointment to Mouse Model of Hemorrhoids

To study the protective effect of hemorrhoids magnetic ointment on mice with hemorrhoids induced by acetic acid...

2022-02-01
【Animal Modeling】-Effects of Electroacupuncture on Synaptic Plasticity and Microglia Polarization in Rats with Cerebral Ischemia

【Animal Modeling】-Effects of Electroacupuncture on Synaptic Plasticity and Microglia Polarization in Rats with Cerebral Ischemia

Explore the electroacupuncture synaptic plasticity and microglia polarization in rats with focal cerebral ischemia, and detect the expression of miR-21/signal transducer and activator of transcription 3 (STAT3) pathway...

2022-02-01
【Animal Modeling】-Von Willebrand Disease Mini Pig Model

【Animal Modeling】-Von Willebrand Disease Mini Pig Model

A research team led by Zhou Qi, a researcher at the Institute of Zoology, Chinese Academy of Sciences, obtained vWF knockout pigs for the first time using CRISPR/Cas9 technology and established a miniature pig model of von Willebrand disease...

2022-02-01
【Animal Modeling】-Effect of alcohol exposure during pregnancy on basic rhythmic respiratory discharge in medulla oblongata of newborn rats

【Animal Modeling】-Effect of alcohol exposure during pregnancy on basic rhythmic respiratory discharge in medulla oblongata of newborn rats

To investigate the effect of alcohol exposure during pregnancy on basic rhythmic respiratory discharge activity (RRDA) in the medulla oblongata slices of offspring of newborn rats...

2022-02-01
Skin stem cells cultivated human 【mini】hearts, which will replace animal experiments in the future

Skin stem cells cultivated human 【mini】hearts, which will replace animal experiments in the future

American scientists have genetically recombined pluripotent stem cells extracted from human skin and cultivated a microventricle with human heart cells...

2022-02-01
【Animal Modeling】-The effect of estrogen and progesterone on the induced differential expression of αvβ3 in bovine endometrial epithelial cells in vitro

【Animal Modeling】-The effect of estrogen and progesterone on the induced differential expression of αvβ3 in bovine endometrial epithelial cells in vitro

To study the changes in the induced differential expression of integrin αvβ3 gene in bovine uterine epithelial cells cultured in vitro, in order to provide a reference for exploring the marker protein of bovine uterine receptivity?...

2022-02-01
[Animal Modeling]-The combined effect of estrogen and androgen on the blood lipid level and coagulation function of hyperlipidemia mice

[Animal Modeling]-The combined effect of estrogen and androgen on the blood lipid level and coagulation function of hyperlipidemia mice

To explore the effect of combined action of estrogen and androgen on blood lipid level and coagulation function in hyperlipidemia mice...

2022-02-01
【Animal Modeling】-Hr gene knockout mouse model construction and phenotype analysis

【Animal Modeling】-Hr gene knockout mouse model construction and phenotype analysis

Establishment of knockout mice for detailed study of the function of hairless genes (Hr)...

2022-02-01