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Through loperamide hydrochloride-induced slow transit constipation mouse model, compare the differences between the models induced by different doses and different administration times, and explore the establishment of a stable loperamide hydrochlori...
2020-12-09Construct a new type of long-term depression model mouse and compare the advantages and disadvantages of this type of mouse with common depression mouse models...
2020-12-09Establish allergic conjunctivitis mouse models under different antigens, different excitation pathways, and different ages of mice. By comparing the immune response status and screening the best sensitization conditions, it is the establishment of al...
2020-12-09Use a new type of hyperlipidemia susceptible rat to establish a non-alcoholic fatty liver disease model, observe the changes in blood biochemical indicators and pathological characteristics, explore its application and scientific research value, and ...
2020-12-09Use patient-derived cells (PDCs) of clear cell renal cancer cells to establish tumor animal models, detect the sensitivity of ccRCC PDCs to molecular targeted drugs, and provide theoretical and experimental basis for clinical diagnosis and treatment...
2020-12-09As an important way of early social deprivation, mother-infant separation has always been a classic animal model for studying the neurobiological mechanism of the adverse effects of early life stress on the individual\'s physiology and psychology...
2020-12-09Using liquid feed to establish a mouse model of alcoholic cardiomyopathy, providing a good animal model for the study of the mechanism of alcoholic cardiomyopathy...
2020-12-09
Previous studies have shown that transgenic mice expressing human ACE2 are highly susceptible to SARS-CoV infection...
2020-12-09To explore the method of making myocardial iron deposition animal model and the relationship between the iron deposition law of the heart and liver...
2020-12-09To study the regulatory effect and mechanism of silencing miR-16 on the immune function of pulmonary tuberculosis model mice...
2020-12-09A rat model of chronic obstructive pulmonary disease (COPD) was constructed by smoking method, protease instillation and a combination of the two methods, and the effect of the model was evaluated from the aspects of inflammation, imaging, and pathol...
2020-12-09Compare the changes in reproduction and development indexes of female rats after giving different doses and times of cyclophosphamide before mating, and establish a standardized positive control model for fertility and early embryonic developmental t...
2020-12-09
Tuberculosis meningitis (TBM) accounts for about 5%-10% of extrapulmonary tuberculosis cases and 1% of all active tuberculosis cases. It is the most deadly form of tuberculosis...
2020-12-09Analyze the modeling elements of asthma animal models, and provide methodological references for improving the success rate of modeling and effectively evaluating the tested drugs...
2020-12-09Evaluate the real-time fluorescent quantitative RT-PCR method of dengue virus and apply it to the detection of key indicators of dengue fever mouse models...
2020-12-09To construct a highly metastatic human hepatocellular carcinoma cell line labeled with Luc￣GFP, two methods to establish an orthotopic liver cancer model in nude mice that is convenient for observation and spontaneously metastasized...
2020-12-09