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【Animal modeling】-The role and mechanism of miR-221 in H2O2-induced myocardial cell injury in rats

【Animal modeling】-The role and mechanism of miR-221 in H2O2-induced myocardial cell injury in rats

To investigate the role and mechanism of miR-221 in hydrogen peroxide (H2O2)-induced rat cardiomyocyte (H9c2) injury...

2022-07-19
【Animal Modeling】-Deoxypurobacterin inhibits the proliferation and induces apoptosis of colon cancer TH29 cells and its mechanism

【Animal Modeling】-Deoxypurobacterin inhibits the proliferation and induces apoptosis of colon cancer TH29 cells and its mechanism

To investigate the inhibition of proliferation and induction of apoptosis of human colon cancer HT29 cells by deoxyvioletine and its possible mechanism...

2022-07-19
【Animal Modeling】-Deoxypurobacterin inhibits the proliferation and induces apoptosis of colon cancer TH29 cells and its mechanism

【Animal Modeling】-Deoxypurobacterin inhibits the proliferation and induces apoptosis of colon cancer TH29 cells and its mechanism

To investigate the inhibition of proliferation and induction of apoptosis of human colon cancer HT29 cells by deoxyvioletine and its possible mechanism...

2022-07-19
【Animal modeling】-Comparison of calcium chelated collagen polypeptide and estrogen on bone improvement in ovariectomized rats

【Animal modeling】-Comparison of calcium chelated collagen polypeptide and estrogen on bone improvement in ovariectomized rats

To compare the bone-improving effect of calcium chelated collagen polypeptide (CPCC) with that of estrogen, and to lay a foundation for the research and development of safe osteoporosis prevention and treatment drugs...

2022-07-19
【Animal modeling】-Effect of telmisartan on the expression of PPARs and adiponectin receptor 2 in liver tissue of rats with non-alcoholic fatty liver disease

【Animal modeling】-Effect of telmisartan on the expression of PPARs and adiponectin receptor 2 in liver tissue of rats with non-alcoholic fatty liver disease

To investigate the effect of telmisartan on the expression of PPARs and adiponectin receptor 2 in liver tissue of rats with non-alcoholic fatty liver disease...

2022-07-19
【Animal modeling】-Anti-fatigue effect of maca extract on sports

【Animal modeling】-Anti-fatigue effect of maca extract on sports

To investigate the anti-fatigue effect of maca extract on sports...

2022-07-19
【Animal Modeling】-Effect of ovariectomy on skin aging in osteoporotic rats

【Animal Modeling】-Effect of ovariectomy on skin aging in osteoporotic rats

The osteoporosis model constructed by ovariectomized rats is the most suitable model for the study of postmenopausal osteoporosis. However, there is little research on the effect of ovariectomized rats on the skin. The purpose of this study was to ob...

2022-07-19
【Animal modeling】-Observation on the effect of improved anesthesia on goat anesthesia

【Animal modeling】-Observation on the effect of improved anesthesia on goat anesthesia

To observe the anesthesia effect of the improved anesthesia method by comparing it with the original goat anesthesia method, and to provide theoretical and practical reference for goat anesthesia during animal modeling...

2022-07-19
【Animal modeling】-Analysis of the localization and expression of vitamin D receptor in the duodenum of C57BL/6 mice

【Animal modeling】-Analysis of the localization and expression of vitamin D receptor in the duodenum of C57BL/6 mice

To investigate the localization and expression of vitamin D receptors in the duodenum of C57BL/6 mice, and to study the correlation between vitamin D system and intestinal development...

2022-07-19
【Animal Modeling】-Hydrogen-rich liquid attenuates cerebral ischemia-reperfusion injury in rats through PI3K pathway

【Animal Modeling】-Hydrogen-rich liquid attenuates cerebral ischemia-reperfusion injury in rats through PI3K pathway

To investigate the effect of hydrogen-rich solution on the apoptosis of hippocampal neurons and the expression of PI3K/Akt/FoxO1 signaling pathway induced by cerebral ischemia-reperfusion in rats...

2022-07-19
【Animal modeling】-Preparation of rat thoracic aortic vascular smooth muscle cells by an improved two-step compound enzyme digestion method

【Animal modeling】-Preparation of rat thoracic aortic vascular smooth muscle cells by an improved two-step compound enzyme digestion method

This paper reports an improved method for the isolation of rat thoracic aortic vascular smooth muscle cells based on compound enzymatic digestion...

2022-07-19
【Animal Modeling】-High-throughput sequencing to study the effects of drinking water with different pH on the intestinal microbes of SPF mice

【Animal Modeling】-High-throughput sequencing to study the effects of drinking water with different pH on the intestinal microbes of SPF mice

To study the effects of drinking water with different pH on gut microbial diversity in SPF mice...

2022-07-19
【Animal Modeling】-DB11/T828.3-2011 Chromosome 12 Marker Screening and Applicability Evaluation Research

【Animal Modeling】-DB11/T828.3-2011 Chromosome 12 Marker Screening and Applicability Evaluation Research

To screen the vacant chromosome 12 markers in the local standard for genetic quality control of Beijing miniature pigs DB11/T828.3-2011, and to analyze the applicability of landmarks by comparing the genetic evaluation of different markers in the sam...

2022-07-19
【Animal Modeling】-Discussion on the mode of administration of cyclophosphamide in rabbit embryo-fetal developmental toxicity test

【Animal Modeling】-Discussion on the mode of administration of cyclophosphamide in rabbit embryo-fetal developmental toxicity test

To investigate the effects of different administration routes and doses of cyclophosphamide on the embryos and fetuses of pregnant rabbits, so as to determine the best administration method for inducing fetal malformation in rabbits...

2022-07-19
【Animal Modeling】-Effect of Bushen Bujing Recipe on Tripterygium wilfordii polyglycosides-induced premature ovarian failure rat model

【Animal Modeling】-Effect of Bushen Bujing Recipe on Tripterygium wilfordii polyglycosides-induced premature ovarian failure rat model

Primary hypogonadism is defined as ovarian insufficiency with high serum follicle-stimulating hormone (FSH) levels. In women, one of the most common forms of primary hypogonadism is premature ovarian failure (POF), also known as premature menopause...

2022-07-19
【Animal modeling】-Protective effect of GDF11 on myocardial injury in type II diabetic mice

【Animal modeling】-Protective effect of GDF11 on myocardial injury in type II diabetic mice

To observe the protective effect of GDF11 on myocardial injury in C57BL/6J mice with type Ⅱ diabetes mellitus and the changes of myocardial apoptosis...

2022-07-19