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【Animal Modeling】-Effect of high-fat diet-induced obesity on ovarian function in female reproductive rats

【Animal Modeling】-Effect of high-fat diet-induced obesity on ovarian function in female reproductive rats

To evaluate the effect of high-fat diet-induced obesity on ovarian function in female rats, and to explore its mechanism...

2022-02-15
【Animal Modeling】-Effect of chronic PM2.5 exposure on lung inflammation and NLRP3 inflammasome activity in C57BL/6J mice

【Animal Modeling】-Effect of chronic PM2.5 exposure on lung inflammation and NLRP3 inflammasome activity in C57BL/6J mice

To study the effects of chronic PM2.5 exposure on pneumonia and NLRP3 inflammasome activity in mice, and to provide new targets for the prevention and treatment of PM2.5-induced lung injury...

2022-02-15
【Animal Modeling】-Therapeutic effect of puerarin on acute liver failure in mice and its mechanism of action

【Animal Modeling】-Therapeutic effect of puerarin on acute liver failure in mice and its mechanism of action

To investigate the protective effect of puerarin on D-galactosamine-induced acute liver failure in mice and to preliminarily observe its mechanism...

2022-02-15
【Animal modeling】-The effect of amputation trauma on cardiac electrophysiology, cardiac function and eNOS pathway in rats

【Animal modeling】-The effect of amputation trauma on cardiac electrophysiology, cardiac function and eNOS pathway in rats

To investigate the changes of cardiac electrophysiology and cardiac function after amputation in rats and their relationship with endothelial nitric oxide synthase/nitric oxide (eNOS/NO) pathway...

2022-02-15
【Animal modeling】-P38MAPK changes and immunoregulatory effects in diarrhea-predominant irritable bowel syndrome rats

【Animal modeling】-P38MAPK changes and immunoregulatory effects in diarrhea-predominant irritable bowel syndrome rats

To investigate the immune regulation of p38MAPK signaling in diarrhea-predominant irritable bowel syndrome rats...

2022-02-14
【Animal modeling】-Anti-atherosclerosis and cardioprotective effects of perilla seed extract in ApoE-/- mice

【Animal modeling】-Anti-atherosclerosis and cardioprotective effects of perilla seed extract in ApoE-/- mice

To study the effect and molecular mechanism of perilla seed oily extract (PSO) on reducing plaque formation and cardioprotection in ApoE-/- mice...

2022-02-14
【Animal Modeling】-Comparison of intravenous injection needle and self-made PE-50 needle in the measurement of intracavernous pressure in rats

【Animal Modeling】-Comparison of intravenous injection needle and self-made PE-50 needle in the measurement of intracavernous pressure in rats

To investigate the method of electrical stimulation of the cavernosal nerve of the penis to detect the intracavernous pressure, and to compare the differences between the two materials (PE-50 tube needle and intravenous infusion needle) for detecting...

2022-02-14
【Animal modeling】-Effect of busulfan on peripheral blood cells and bone marrow cells of type 2 diabetic KKAy mice

【Animal modeling】-Effect of busulfan on peripheral blood cells and bone marrow cells of type 2 diabetic KKAy mice

To observe the damage effect of busulfan on the hematopoietic function of type 2 diabetes model KK/upj-Ay/J mice, and to compare with the control C57BL/6J(B6) mice...

2022-02-14
【Animal Modeling】-Neuron \"Super Replacement\" Restores Vision in Blind Mice

【Animal Modeling】-Neuron "Super Replacement" Restores Vision in Blind Mice

Once it grows, it will last a lifetime. Even if some parts are worn out, there is almost no possibility of replacement...

2022-02-14
【Animal modeling】-Discuss the protective effect and mechanism of activated protein C on myocardial ischemia-reperfusion injury in rats

【Animal modeling】-Discuss the protective effect and mechanism of activated protein C on myocardial ischemia-reperfusion injury in rats

To investigate the protective effect and mechanism of activated protein C (APC) on myocardial ischemia-reperfusion injury in rats...

2022-02-14
【Animal modeling】-Effect of hydroxychloroquine on spleen lymphocytes in lupus mice

【Animal modeling】-Effect of hydroxychloroquine on spleen lymphocytes in lupus mice

To observe the effect of hydroxychloroquine on the distribution of lymphocytes in peripheral immune organs (spleen) of mice with systemic lupus erythematosus (TC mice)...

2022-02-14
【Animal Modeling】-Study on the antitumor effect of Xiuzhen mushroom powder on H22 tumor-bearing mice in vivo

【Animal Modeling】-Study on the antitumor effect of Xiuzhen mushroom powder on H22 tumor-bearing mice in vivo

The purpose of this experiment was to study the anti-tumor effect of Xiuzhen Mushroom and its anti-tumor mechanism...

2022-02-14
【Animal Modeling】-The inhibitory effect of miRNA-144 gene overexpression on hepatocellular carcinoma mice and its influence on intestinal flora

【Animal Modeling】-The inhibitory effect of miRNA-144 gene overexpression on hepatocellular carcinoma mice and its influence on intestinal flora

To analyze the antitumor effect of microRNA-144 (miRNA-144) gene overexpression on hepatocellular carcinoma mice and the effect on intestinal flora...

2022-02-14
【Animal modeling】-Preparation of curcumin nanoemulsion and its protective effect on myocardial ischemia-reperfusion in rats

【Animal modeling】-Preparation of curcumin nanoemulsion and its protective effect on myocardial ischemia-reperfusion in rats

To construct curcumin (CUR) nanoemulsion drug delivery system and study its protective effect and mechanism on myocardial ischemia-reperfusion in rats...

2022-02-14
【Animal Modeling】-Experimental Study on In Vitro Fertilization of Type Ⅰ Interferon Receptor Deficient Mice

【Animal Modeling】-Experimental Study on In Vitro Fertilization of Type Ⅰ Interferon Receptor Deficient Mice

To explore the effect of deletion of two type I interferon receptors on in vitro fertilization in mice and to optimize the conditions of in vitro fertilization...

2022-02-14
【Animal Modeling】-Deletion of MD1 increases the susceptibility to ventricular arrhythmia in obese mice by activating the TLR4/MyD88 signaling pathway

【Animal Modeling】-Deletion of MD1 increases the susceptibility to ventricular arrhythmia in obese mice by activating the TLR4/MyD88 signaling pathway

To investigate the deletion of myeloid differentiation protein 1 (MD1) increases the susceptibility of ventricular arrhythmia in obese mice by activating the Toll-like receptor 4 (TLR4)/myeloid differentiation factor (MyD88) signaling pathway...

2022-02-14