【Animal Modeling】-Regulatory T cell therapy for experimental mouse polymyositis and its mechanism

To investigate the therapeutic value and mechanism of CD4+ CD25+ Foxp3+ Treg cells in experimental autoimmune myositis (EAM) mice...

2022-02-09

【Animal Modeling】-Expression of Transient Receptor Potential Channel 1 in Ozone-induced Lung Tissue Inflammation in Mice

To investigate the expression of canonical transient receptor potential channel 1 (TRPC1) in mouse lung tissue under ozone exposure...

2022-02-09

【Animal modeling】-The inhibitory effect of ursolic acid on the rejection of corneal transplantation in rats

To investigate the therapeutic effect of ursolic acid on corneal transplant rejection in rats...

2022-02-09

【Animal modeling】-The treatment and mechanism of hemin on gestational hypertensive rats

To preliminarily explore the therapeutic effect and possible regulatory mechanism of heme oxygenase inducer hemin (Hemin) in rats with pregnancy-induced hypertension (HDCP)...

2022-02-09

【Animal modeling】- Oral human alpha interferon transforms Bifidobacterium to promote the proliferation and maturation of mouse lymphocytes

To investigate the regulatory effect of human alpha interferon (IFN-α) gene on the immune function of mice after oral administration of Bifidobacterium transformed...

2022-02-09

【Animal modeling】-Edaravone can reduce oxidative stress and delay myocardial fibrosis in rats

To investigate the effect of edaravone on reducing oxidative stress and anti-myocardial fibrosis...

2022-02-09

【Animal modeling】-Recombinant lentivirus-mediated LXRα RNA interference improves the function of rat fatty liver donor liver transplantation

To investigate the effect and mechanism of LXRα RNA interference (RNAi) in improving liver function in rats with fatty liver after liver transplantation...

2022-02-09

【Animal modeling】-Effect of acute incision pain on the expression of connexin Cx43 in the dorsal horn of spinal cord in rats

To observe the effect of acute incision pain on the expression of connexin43 (Cx43) in the dorsal horn of rat spinal cord...

2022-02-09

【Animal Modeling】-Effect of Dexamethasone Pollution in Drinking Water on Intestinal Microflora in Mice

To discuss the effect of dexamethasone pollution in the water environment on the intestinal flora of mice...

2022-02-09

【Animal Modeling】-Effects of propofol on tumor lung metastasis and the expression of MTA1 and Wnt1 in tumor-bearing rats

To discuss the effect of different doses of propofol on the expression of MTA1 and Wnt1 in rat MADB106 cells lung metastasis and tumor tissue...

2022-02-09

【Animal modeling】-Protective effect of ulinastatin on acute lung injury in severe heatstroke mice

To discuss the maintenance effect of ulinastatin on acute lung injury in severe heatstroke mice...

2022-02-09

【Animal modeling】-Subacute inhalation toxicity study of ivermectin original drug in rats

To study the subacute inhalation toxicity of ivermectin original drug to rats and find out the maximum ineffective dose...

2022-02-09

【Animal modeling】-Effect of rapamycin on proliferation of rat aortic valve interstitial cells

To apply rapamycin to target mTOR and discuss its effect on the proliferation of rat heart valve interstitial cells...

2022-02-09

【Animal modeling】-Effect of Ghrelin on the expression of DKK-1 in the hippocampus and learning and memory function of diabetic rats

To observe the expression changes of Ghrelin on DKK-1 and WNT signaling pathways in diabetic rats, and to explore the mechanism involved in learning and memory function...

2022-02-09

【Animal modeling】-Protective effect of piperphentonamine hydrochloride on gentamicin-induced hearing loss in guinea pigs

To investigate the relationship between the expression of autophagy-related proteins beclin1 and LC3, Na+-K+-2Cl-binding transporter (NKCC1) mRNA, endothelin (ET) and cochlear gentamicin (GM) injury in guinea pig cochlea and piperphentonamine hydroch...

2022-02-09

【Animal modeling】-Effect of octachlorodibenzodioxin on gene expression profile of mouse testis tissue

To discuss the effect of octachlorodibenzodioxins on the alteration of gene expression profiles in the testis of male mice...

2022-02-09