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【Animal modeling】-Effect and mechanism of Shenqu Xiaoshi oral liquid on gastrointestinal motility in mice with functional dyspepsia

【Animal modeling】-Effect and mechanism of Shenqu Xiaoshi oral liquid on gastrointestinal motility in mice with functional dyspepsia

To explore the effect and mechanism of Shenqu Xiaoshi Oral Liquid on gastrointestinal motility in functional dyspepsia (FD) mice...

2022-02-11
【Animal modeling】-The effect of paeoniflorin on Bayk8644-induced depression-anxiety-like behavior in rats and its mechanism

【Animal modeling】-The effect of paeoniflorin on Bayk8644-induced depression-anxiety-like behavior in rats and its mechanism

To investigate the pharmacological mechanism of paeoniflorin in improving depression-anxiety-like behavior in rats based on L-type voltage-dependent calcium channel...

2022-02-11
【Animal Model】-Effect of α-mangostin on the immune function of immunosuppressed mice

【Animal Model】-Effect of α-mangostin on the immune function of immunosuppressed mice

To investigate the effect of α-mangostin on the immune function of cyclophosphamide-induced immunosuppression in mice, and to provide experimental basis for the follow-up mechanism research and the development of new drugs to increase immune function...

2022-02-11
To investigate the therapeutic effect of rapamycin on 3,5-diethoxycarbonyl 1,4-dihydrocollidine (DDC)-induced mouse primary sclerosing cholangitis (PSC), and to explore its potential mechanism

To investigate the therapeutic effect of rapamycin on 3,5-diethoxycarbonyl 1,4-dihydrocollidine (DDC)-induced mouse primary sclerosing cholangitis (PSC), and to explore its potential mechanism

To investigate the therapeutic effect of rapamycin on 3,5-diethoxycarbonyl 1,4-dihydrocollidine (DDC)-induced mouse primary sclerosing cholangitis (PSC), and to explore its potential mechanism...

2022-02-11
【Animal modeling】-Protective effect of curcumin on acute kidney injury in pregnant hypertensive rats

【Animal modeling】-Protective effect of curcumin on acute kidney injury in pregnant hypertensive rats

To investigate the protective effect of curcumin on acute kidney injury in rats caused by gestational hypertension and to explore its potential mechanism...

2022-02-11
【Animal Modeling】-Chronic toxicity test of Deinococcus radiodurans R1 in rats

【Animal Modeling】-Chronic toxicity test of Deinococcus radiodurans R1 in rats

To observe the chronic toxicity of Deinococcus radiodurans R1 to SD rats...

2022-02-10
【Animal modeling】-Protective effect of Xiaoxianxiong decoction on vascular endothelium in hyperlipidemic mice

【Animal modeling】-Protective effect of Xiaoxianxiong decoction on vascular endothelium in hyperlipidemic mice

To investigate the effect of Xiaoxianxiong Decoction on vascular endothelial injury in hyperlipidemia mice...

2022-02-10
【Animal Modeling】-Effect of long-term high-protein diet on hepatic steatosis and fat accumulation in OVX mice

【Animal Modeling】-Effect of long-term high-protein diet on hepatic steatosis and fat accumulation in OVX mice

To investigate the effect of long-term high-protein diet on liver and adipose tissue in ovariectomized mice and the effect of glucagon-like peptide-1...

2022-02-10
【Animal modeling】-The protective effect of etomidate on acute lung injury in septic shock rats based on TLR4 pathway

【Animal modeling】-The protective effect of etomidate on acute lung injury in septic shock rats based on TLR4 pathway

To investigate the protective effect of etomidate (Eto) on acute lung injury in rats with septic shock based on the Toll-like receptor 4 (TLR4) pathway...

2022-02-10
【Animal modeling】-Analysis of gentiopicroside on tumor growth inhibition and anti-angiogenesis in H22 liver cancer mice

【Animal modeling】-Analysis of gentiopicroside on tumor growth inhibition and anti-angiogenesis in H22 liver cancer mice

To investigate the inhibitory effect and anti-angiogenesis mechanism of gentiopicroside on H22 liver cancer mice...

2022-02-10
【Animal Modeling】-NOD2 promotes the production of nitrosamine by diethyl nitrosamine to study the mechanism of inducing liver tissue inflammation in mice

【Animal Modeling】-NOD2 promotes the production of nitrosamine by diethyl nitrosamine to study the mechanism of inducing liver tissue inflammation in mice

To investigate the role and mechanism of NOD2, a pattern recognition receptor in hepatocytes, in the process of hepatic inflammation...

2022-02-10
【Animal Modeling】-Effect of REST/NRSF on depression and anxiety-like behavior in corticosterone stress model mice

【Animal Modeling】-Effect of REST/NRSF on depression and anxiety-like behavior in corticosterone stress model mice

To study the expression of REST in corticosterone model mice and the effect of REST expression on depression and anxiety behavior in mice, and to explore its role in the mouse model of depression...

2022-02-10
【Animal Modeling】-Hemophilia Gene Therapy Animal Trials Successfully

【Animal Modeling】-Hemophilia Gene Therapy Animal Trials Successfully

Hemophilia is a disease caused by hereditary coagulation dysfunction, which is characterized by the inability of the body to produce coagulation factors or insufficient production of coagulation factors, resulting in prolonged coagulation time and di...

2022-02-10
【Animal Modeling】-Effect of plantar shock stress duration on anxiety-like behavior in rats

【Animal Modeling】-Effect of plantar shock stress duration on anxiety-like behavior in rats

To observe the effects of plantar shock stress duration on the elevated plus maze and anxiety-like behaviors in the opening test in rats...

2022-02-09
【Animal modeling】-Protective effect of emulsified fluorocarbon combined with ligustrazine on pulmonary ischemia-reperfusion injury in rats

【Animal modeling】-Protective effect of emulsified fluorocarbon combined with ligustrazine on pulmonary ischemia-reperfusion injury in rats

To investigate the effect and mechanism of emulsified fluorocarbon combined with ligustrazine on pulmonary ischemia-reperfusion injury...

2022-02-09
【Animal modeling】-High intensity focused ultrasound inhibits the metastasis of mouse melanoma cells B16-F10 in vivo

【Animal modeling】-High intensity focused ultrasound inhibits the metastasis of mouse melanoma cells B16-F10 in vivo

To investigate the effect of high-intensity focused ultrasound (HIFU) treatment on the in vivo metastasis of melanoma cells in a mouse model of melanoma...

2022-02-09