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【Animal modeling】-Optimization of dose-response relationship between N-ethyl-N-nitrosourea and cyclophosphamide in pig-a gene mutation test in rats

【Animal modeling】-Optimization of dose-response relationship between N-ethyl-N-nitrosourea and cyclophosphamide in pig-a gene mutation test in rats

To study the effect of different doses of N-ethyl-N-nitrosourea (ENU) and cyclophosphamide (CP) on the deletion rate of ankyrin CD59 on the peripheral blood red blood cell surface of SD rats, and to optimize the Pig-a gene mutation test Detection met...

2022-02-18
【Animal modeling】-The protective effect and mechanism of glycyrrhizic acid on hippocampal neuron damage in epileptic rats

【Animal modeling】-The protective effect and mechanism of glycyrrhizic acid on hippocampal neuron damage in epileptic rats

To investigate the protective effect and related mechanism of glycyrrhizic acid on hippocampal neuron damage in epileptic rats...

2022-02-17
【Animal Modeling】- Nutrient Elements and Protein Combined Intervention of Fluorosis on Ovarian Function in Female Rats

【Animal Modeling】- Nutrient Elements and Protein Combined Intervention of Fluorosis on Ovarian Function in Female Rats

To investigate the changes of ovarian function in female mice by the combined intervention of calcium, magnesium, copper, zinc, vitamin D and protein on coal-burning fluorosis...

2022-02-17
【Animal modeling】-Effect of Xuanfei recipe on mTOR/S6K1 signaling pathway in endotoxin-induced acute lung injury in rats

【Animal modeling】-Effect of Xuanfei recipe on mTOR/S6K1 signaling pathway in endotoxin-induced acute lung injury in rats

To observe the effect of Xuanfei Decoction on the mTOR/S6K1 signaling pathway of endotoxin-induced acute lung injury in rats, and to explore its mechanism of action...

2022-02-17
【Animal Modeling】-Myocardial Fibrosis and Changes of Myocardial AGEs/RAGE Levels in Diabetic Rats

【Animal Modeling】-Myocardial Fibrosis and Changes of Myocardial AGEs/RAGE Levels in Diabetic Rats

To study the changes of myocardial fibrosis and myocardial AGEs/RAGE levels by constructing a type Ⅱ diabetic rat model...

2022-02-17
【Animal modeling】-Study on the effect of compound Ejiao paste on the endometrium of mice

【Animal modeling】-Study on the effect of compound Ejiao paste on the endometrium of mice

To investigate the effect of Compound Ejiao paste on the endometrium of mice...

2022-02-17
【Animal modeling】-Effect of curcumin pretreatment on myocardial oxidative stress and apoptosis in rats with heat stroke in dry heat environment

【Animal modeling】-Effect of curcumin pretreatment on myocardial oxidative stress and apoptosis in rats with heat stroke in dry heat environment

To observe the effects of curcumin pretreatment on myocardial oxidative stress and apoptosis in rats with heat stroke in a dry heat environment and explore its possible mechanism...

2022-02-16
【Animal modeling】-Effect of lentiviral vector-mediated HCV receptor gene OCLN/CD81 transfection on tree shrew bone marrow mesenchymal stem cells

【Animal modeling】-Effect of lentiviral vector-mediated HCV receptor gene OCLN/CD81 transfection on tree shrew bone marrow mesenchymal stem cells

To observe the effects of lentiviral vector-mediated HCV receptor gene OCLN/CD81 transfection on the biological characteristics and gene expression of tree shrew bone marrow mesenchymal stem cells under in vitro culture conditions...

2022-02-16
【Animal Modeling】-Visual assessment of microcirculation after acute myocardial infarction in rabbits by contrast echocardiography

【Animal Modeling】-Visual assessment of microcirculation after acute myocardial infarction in rabbits by contrast echocardiography

To evaluate the blood perfusion status of the infarcted segment after acute myocardial infarction using the visual assessment method of myocardial contrast echocardiography in a rabbit model of acute myocardial infarction...

2022-02-16
【Animal modeling】-Study on the protective effect of morroniside administered 24 hours after operation on focal cerebral ischemia-reperfusion in rats

【Animal modeling】-Study on the protective effect of morroniside administered 24 hours after operation on focal cerebral ischemia-reperfusion in rats

To study the effect of morroniside on angiogenesis-related factors and neurological function 24 hours after focal cerebral ischemia-reperfusion in rats...

2022-02-16
【Animal Model】-Effect of X-ray whole body irradiation on the function of hematopoietic immune system in KKAy mice with type 2 diabetes

【Animal Model】-Effect of X-ray whole body irradiation on the function of hematopoietic immune system in KKAy mice with type 2 diabetes

To observe the damage effect of X-ray whole body irradiation on the function of hematopoietic immune system in KKAy mice, a model of type 2 diabetes mellitus, and compare it with the control C57 mice...

2022-02-15
【Animal modeling】-Effect of vitamin E on myocardial injury after renal ischemia-reperfusion in rats

【Animal modeling】-Effect of vitamin E on myocardial injury after renal ischemia-reperfusion in rats

To investigate the effect of vitamin E on myocardial injury after renal ischemia-reperfusion in rats...

2022-02-15
【Animal Modeling】-Effect of Maiqi Jiangtang Pill on blood sugar in ob/ob mice

【Animal Modeling】-Effect of Maiqi Jiangtang Pill on blood sugar in ob/ob mice

To study the effect of Maiqi Jiangtang Pills on blood sugar in ob/ob mice...

2022-02-15
【Animal modeling】-Effect of Fujiutie ointment on the expression of NGF/TrKA and related inflammatory factors in asthmatic mice

【Animal modeling】-Effect of Fujiutie ointment on the expression of NGF/TrKA and related inflammatory factors in asthmatic mice

To observe the effect of preparation \"Fujiu Tie Gao\" on serum interleukin-4, interferon γ, related immunoglobulin E cytokines, nerve growth factor and tyrosine kinase A protein expressions in lung tissue of asthmatic mice, and to explore ...

2022-02-15
【Animal modeling】-Effect of acute exercise on the expression of miRNA-30a in rat myocardium

【Animal modeling】-Effect of acute exercise on the expression of miRNA-30a in rat myocardium

To study the effect of acute exercise on myocardial miRNA-30a and the expression of autophagy-related genes in rats, and to explore the regulatory mechanism of miRNA-30a on myocardial autophagy activity in different recovery periods after exercise...

2022-02-15
【Animal modeling】-Protective effect of trigonelline on testicular injury induced by heat stress in mice

【Animal modeling】-Protective effect of trigonelline on testicular injury induced by heat stress in mice

To study the protective effect of trigonelline on heat stress-induced testicular injury in mice...

2022-02-15