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【Animal Modeling】-The effect of icariin on experimental IgA nephropathy in rats and related mechanisms

【Animal Modeling】-The effect of icariin on experimental IgA nephropathy in rats and related mechanisms

To explore the effects of different doses of icariin on rats with experimental IgA nephropathy, and to study its related mechanism...

2022-02-22
【Animal modeling】-Effect of deoxycholic acid on the growth of ileal organoids in C57BL/6 mice

【Animal modeling】-Effect of deoxycholic acid on the growth of ileal organoids in C57BL/6 mice

To establish a mouse intestinal organoid culture system, and to investigate the effect of deoxycholic acid (DCA) on the growth of intestinal organoids...

2022-02-22
【Animal modeling】-Protective effect of nimodipine on H2O2-induced apoptosis of PC12 cells

【Animal modeling】-Protective effect of nimodipine on H2O2-induced apoptosis of PC12 cells

To investigate the protective effect of nimodipine on the apoptosis of PC12 cells induced by hydrogen peroxide (H2O2)...

2022-02-21
【Animal Modeling】-Mechanism of platelets in salt-sensitive hypertension through inflammatory response

【Animal Modeling】-Mechanism of platelets in salt-sensitive hypertension through inflammatory response

To explore the role and molecular mechanism of platelets in high-salt-induced salt-sensitive hypertension...

2022-02-21
【Animal modeling】-Observation on the effect of improved anesthesia on goat anesthesia

【Animal modeling】-Observation on the effect of improved anesthesia on goat anesthesia

To observe the anesthesia effect of the improved anesthesia method by comparing it with the original goat anesthesia method, and to provide theoretical and practical reference for goat anesthesia during animal modeling...

2022-02-21
【Animal Modeling】-Hydrogen-rich liquid attenuates cerebral ischemia-reperfusion injury in rats through PI3K pathway

【Animal Modeling】-Hydrogen-rich liquid attenuates cerebral ischemia-reperfusion injury in rats through PI3K pathway

To investigate the effect of hydrogen-rich solution on the apoptosis of hippocampal neurons and the expression of PI3K/Akt/FoxO1 signaling pathway induced by cerebral ischemia-reperfusion in rats...

2022-02-21
【Animal modeling】-Preparation of rat thoracic aortic vascular smooth muscle cells by an improved two-step compound enzyme digestion method

【Animal modeling】-Preparation of rat thoracic aortic vascular smooth muscle cells by an improved two-step compound enzyme digestion method

This paper reports an improved method for the isolation of rat thoracic aortic vascular smooth muscle cells based on compound enzymatic digestion...

2022-02-21
【Animal Modeling】-Discussion on the mode of administration of cyclophosphamide in rabbit embryo-fetal developmental toxicity test

【Animal Modeling】-Discussion on the mode of administration of cyclophosphamide in rabbit embryo-fetal developmental toxicity test

To investigate the effects of different administration routes and doses of cyclophosphamide on the embryos and fetuses of pregnant rabbits, so as to determine the best administration method for inducing fetal malformation in rabbits...

2022-02-21
【Animal modeling】-Protective effect of GDF11 on myocardial injury in type II diabetic mice

【Animal modeling】-Protective effect of GDF11 on myocardial injury in type II diabetic mice

To observe the protective effect of GDF11 on myocardial injury and the changes of myocardial apoptosis in C57BL/6J mice with type Ⅱ diabetes...

2022-02-21
【Animal Modeling】-The effect of exercise on pancreatic islets in diabetic rats and its mechanism

【Animal Modeling】-The effect of exercise on pancreatic islets in diabetic rats and its mechanism

To investigate the effect of aerobic exercise on pancreatic islets and β cells in type 2 diabetic rats and its mechanism...

2022-02-21
【Animal modeling】The effect of -1α,25(OH)2D3 on the expression of lubricin in rat articular chondrocytes

【Animal modeling】The effect of -1α,25(OH)2D3 on the expression of lubricin in rat articular chondrocytes

To investigate the effect of 1α,25(OH)2D3 on the synthesis and secretion of lubricin in chondrocytes at the cellular level...

2022-02-21
【Animal modeling】-Flow cytometry analysis of the phenotypic characteristics of PMA-induced THP-1 differentiation into macrophages

【Animal modeling】-Flow cytometry analysis of the phenotypic characteristics of PMA-induced THP-1 differentiation into macrophages

To clarify the differentiation of macrophages derived from THP-1 cells induced by PMA alone by flow cytometry...

2022-02-21
【Animal modeling】-The effect of platelet-rich plasma on rabbit Achilles tendon healing

【Animal modeling】-The effect of platelet-rich plasma on rabbit Achilles tendon healing

Surgical treatment of acute Achilles tendon rupture includes early accelerated rehabilitation, which shortens the fixation period and allows early range exercise and muscle strengthening exercises...

2022-02-19
【Animal Modeling】-The effect of methylene blue and sevoflurane on serum and lung tissue oxidative stress indicators and inflammatory factors in a rat model of lung ischemia-reperfusion (IR) injury

【Animal Modeling】-The effect of methylene blue and sevoflurane on serum and lung tissue oxidative stress indicators and inflammatory factors in a rat model of lung ischemia-reperfusion (IR) injury

To study the effects of methylene blue and sevoflurane on oxidative stress indicators and inflammatory factors in serum and lung tissue of rats with lung ischemia-reperfusion (IR) injury...

2022-02-19
[Animal Modeling]-Epileptic mouse model of primary epilepsy

[Animal Modeling]-Epileptic mouse model of primary epilepsy

The replication method is to measure the degree of epileptic seizures of the mice before the experiment and select suitable experimental animals...

2022-02-19
【Animal Modeling】-L-glutamic acid induces neonatal rat-dependent retinal toxicity

【Animal Modeling】-L-glutamic acid induces neonatal rat-dependent retinal toxicity

Glutamate, an excitatory neurotransmitter in the retina, is known to cause excitotoxicity, in which neuronal cell death occurs after excessive excitatory neurotransmitter....

2022-02-19