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【Animal modeling】-Effect of dexmedetomidine pretreatment on inflammatory factors and oxidative stress in rats with septic kidney injury

【Animal modeling】-Effect of dexmedetomidine pretreatment on inflammatory factors and oxidative stress in rats with septic kidney injury

To investigate the effect of dexmedetomidine on inflammatory factors and oxidative stress of AKI (acute kidney injury) in septic rats...

2022-02-28
【Animal modeling】-New polycitric acid filler material induces soft tissue regeneration after rat skull defect

【Animal modeling】-New polycitric acid filler material induces soft tissue regeneration after rat skull defect

To evaluate the ability of two novel polycitric acid degradable biomaterials to induce soft tissue regeneration after calvarial defect in rats...

2022-02-28
【Animal Modeling】-Experimental study of CD45 mAb-mediated 188Re-avidin two-step pretargeting targeting lymphoma

【Animal Modeling】-Experimental study of CD45 mAb-mediated 188Re-avidin two-step pretargeting targeting lymphoma

To establish a CD45 mAb-mediated two-step pre-localization method for 188Re-avidin, observe its biological distribution in tumor-bearing mice, and evaluate its feasibility in the treatment of lymphoma...

2022-02-28
【Animal Modeling】-Research on the antidepressant mechanism of licorice and its application in animal behavior

【Animal Modeling】-Research on the antidepressant mechanism of licorice and its application in animal behavior

Depression, also known as \"emotional cold\", is a common affective disorder characterized by persistent low mood...

2022-02-28
【Animal modeling】-Protective effect of myricetin on ischemia-reperfusion injury in isolated rat hearts

【Animal modeling】-Protective effect of myricetin on ischemia-reperfusion injury in isolated rat hearts

To study the protective effect and mechanism of myricetin on ischemia-reperfusion injury in isolated rat hearts...

2022-02-28
【Animal Modeling】-Effect of subchronic exposure to diflubenzuron on the blood system of rats

【Animal Modeling】-Effect of subchronic exposure to diflubenzuron on the blood system of rats

Based on the study of the subchronic oral toxicity of diflubenzuron to rats, the effect on the blood system of rats after exposure was preliminarily discussed...

2022-02-28
【Animal modeling】-Foxo3a gene regulates the development of rat ovarian granulosa cells in vitro and prevents the toxic effect of cisplatin on the ovary

【Animal modeling】-Foxo3a gene regulates the development of rat ovarian granulosa cells in vitro and prevents the toxic effect of cisplatin on the ovary

To study the regulation of Foxo3a gene on the development of rat ovarian granulosa cells in vitro and its preventive effect on the ovarian toxicity of cisplatin...

2022-02-25
【Animal Modeling】-Effect of Maca Extract on Toxicity and Immune Organs of Mice

【Animal Modeling】-Effect of Maca Extract on Toxicity and Immune Organs of Mice

To investigate the effects of maca extract on the toxicity and immune organs of mice...

2022-02-25
【Animal modeling】-Effect of tacrolimus on the expression of rat liver tissue protein phosphatase 2A and P-AKT

【Animal modeling】-Effect of tacrolimus on the expression of rat liver tissue protein phosphatase 2A and P-AKT

By observing the effects of tacrolimus on blood glucose, insulin levels, hepatic tissue protein phosphatase 2A and phosphorylated AKT expression in rats, to further explore the mechanism of tacrolimus-induced blood glucose elevation...

2022-02-25
【Animal Modeling】-Effect and mechanism of propofol intervention on optic nerve injury in rats

【Animal Modeling】-Effect and mechanism of propofol intervention on optic nerve injury in rats

To investigate the effect and mechanism of propofol intervention on the injured optic nerve and retinal ganglia after optic nerve injury in rats...

2022-02-25
【Animal modeling】-Effect of miR-126 on myocardial cell apoptosis in rats with acute myocardial infarction

【Animal modeling】-Effect of miR-126 on myocardial cell apoptosis in rats with acute myocardial infarction

To investigate the effect of miR-126 on myocardial cell apoptosis in acute myocardial infarction (AMI) rats...

2022-02-25
【Animal Modeling】-Comparison of the effect of gene therapy and traditional non-surgical therapy on postpartum stress urinary incontinence model rats

【Animal Modeling】-Comparison of the effect of gene therapy and traditional non-surgical therapy on postpartum stress urinary incontinence model rats

To study the effect of TGF-β1 gene therapy on rat model of postpartum stress urinary incontinence, and to explore the ideal new non-surgical treatment method for the disease...

2022-02-25
【Animal Modeling】-SOD activity of diabetic rats and the effect of antioxidant treatment on the antioxidant status of the body

【Animal Modeling】-SOD activity of diabetic rats and the effect of antioxidant treatment on the antioxidant status of the body

To explore the changes of SOD activity and protein expression in main organs of diabetic rats, and to observe the effect of the antioxidant N-acetylcysteine (NAC) on the antioxidant status of the body after short-term treatment (4 weeks)...

2022-02-25
【Animal Modeling】-Effect of Trichinella spiralis and its worm-derived protein on cecal ligation and puncture-induced sepsis in mice

【Animal Modeling】-Effect of Trichinella spiralis and its worm-derived protein on cecal ligation and puncture-induced sepsis in mice

To observe the effect of Trichinella spiralis and its parasite-derived protein on cecal ligation and puncture (CLP)-induced sepsis in mice...

2022-02-25
【Animal modeling】-Protective effect of liraglutide on stress-stressed chronic heart failure in rats

【Animal modeling】-Protective effect of liraglutide on stress-stressed chronic heart failure in rats

To study the effect and mechanism of liraglutide on cardiac function in pressure-stressed chronic heart failure rats...

2022-02-25
【Animal Model】-Diabetic Retinopathy Model

【Animal Model】-Diabetic Retinopathy Model

NOD xiǎo shǔ shì yánjiū rénlèi 1 xíng tángniàobìng zuì hǎo de móxíng, qí zài yíchuán hé miǎnyì fāngmiàn yǔ rénlèi jíqí xiāngsì 37/5000 NOD mice are the best model for studying human type 1 diabetes, which is very similar to humans in terms of genet...

2022-02-24