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【Animal modeling】-nicotine inhibits MIA-induced apoptosis of rat osteoarthritis chondrocytes

【Animal modeling】-nicotine inhibits MIA-induced apoptosis of rat osteoarthritis chondrocytes

To investigate the inhibition of nicotine on the apoptosis of osteoarthritis chondrocytes induced by sodium iodoacetate (MIA)...

2022-07-21
【Animal Modeling】-Research on the standard of abnormal toxicity of Asarum injection preparations detected by mice

【Animal Modeling】-Research on the standard of abnormal toxicity of Asarum injection preparations detected by mice

To determine the LD50 value of mice intravenously administered with Asarum injection preparation, and to draft the abnormal toxicity inspection standard of this product...

2022-07-21
【Animal modeling】-Construction and effect evaluation of Noggin gene silencing expression vector

【Animal modeling】-Construction and effect evaluation of Noggin gene silencing expression vector

To construct lentivirus-mediated Noggin RNAi interference sequences, and to analyze the silencing effect of these interference sequences on Noggin gene...

2022-07-21
【Animal modeling】-Propofol protects against cerebral ischemia-reperfusion injury and may be related to the inhibition of gap junction function

【Animal modeling】-Propofol protects against cerebral ischemia-reperfusion injury and may be related to the inhibition of gap junction function

To investigate the relationship between the protective effect of propofol on cerebral ischemia-reperfusion injury and gap junctions and its possible mechanism...

2022-07-21
【Animal modeling】-New polycitric acid filler material induces soft tissue regeneration after rat skull defect

【Animal modeling】-New polycitric acid filler material induces soft tissue regeneration after rat skull defect

To evaluate the ability of two novel polycitric acid degradable biomaterials to induce soft tissue regeneration after calvarial defect in rats...

2022-07-21
【Animal modeling】-Effect of dexmedetomidine pretreatment on inflammatory factors and oxidative stress in rats with septic kidney injury

【Animal modeling】-Effect of dexmedetomidine pretreatment on inflammatory factors and oxidative stress in rats with septic kidney injury

To investigate the effect of dexmedetomidine on inflammatory factors and oxidative stress of AKI (acute kidney injury) in septic rats...

2022-07-21
【Animal Modeling】-Vitamin C enhances the proliferation of BMSCs derived from aging individuals in SAMP6 mice

【Animal Modeling】-Vitamin C enhances the proliferation of BMSCs derived from aging individuals in SAMP6 mice

To observe whether vitamin C (Vc) can promote the proliferation of bone marrow mesenchymal stem cells derived from aging individuals by increasing telomerase activity...

2022-07-21
【Animal modeling】-Propofol protects against cerebral ischemia-reperfusion injury and may be related to the inhibition of gap junction function

【Animal modeling】-Propofol protects against cerebral ischemia-reperfusion injury and may be related to the inhibition of gap junction function

To investigate the relationship between the protective effect of propofol on cerebral ischemia-reperfusion injury and gap junctions and its possible mechanism...

2022-07-21
【Animal modeling】-New polycitric acid filler material induces soft tissue regeneration after rat skull defect

【Animal modeling】-New polycitric acid filler material induces soft tissue regeneration after rat skull defect

To evaluate the ability of two novel polycitric acid degradable biomaterials to induce soft tissue regeneration after calvarial defect in rats...

2022-07-21
【Animal Modeling】-Experimental study of CD45 mAb-mediated 188Re-avidin two-step pretargeting targeting lymphoma

【Animal Modeling】-Experimental study of CD45 mAb-mediated 188Re-avidin two-step pretargeting targeting lymphoma

To establish a CD45 mAb-mediated two-step pre-localization method for 188Re-avidin, to observe its biological distribution in tumor-bearing mice, and to evaluate its feasibility in the treatment of lymphoma...

2022-07-21
【Animal modeling】The effect and mechanism of -2,3-butanedione monooxime in improving abnormal calcium injury in isolated rat heart

【Animal modeling】The effect and mechanism of -2,3-butanedione monooxime in improving abnormal calcium injury in isolated rat heart

To investigate the effect and mechanism of contracture inhibitor 2,3-butanedione monooxime in improving abnormal calcium injury in isolated rat hearts...

2022-07-21
【Animal modeling】-Solanine inhibits the growth of nude mouse prostate cancer cell Du145 xenografts by inducing cell cycle G1/S arrest

【Animal modeling】-Solanine inhibits the growth of nude mouse prostate cancer cell Du145 xenografts by inducing cell cycle G1/S arrest

To investigate the effect and molecular mechanism of solanine on the growth of prostate cancer cell Du145 transplanted in nude mice...

2022-07-21
【Animal Modeling】-Research on the antidepressant mechanism of licorice and its application in animal behavior

【Animal Modeling】-Research on the antidepressant mechanism of licorice and its application in animal behavior

Depression, also known as \"emotional cold\", is a common affective disorder characterized by persistent low mood. The clinical manifestations are depression, loss of various interests and pleasures, and are often accompanied by physical sy...

2022-07-21
【Animal modeling】-Effect of camel milk on glucose and lipid metabolism and PPAR-γ, TNF-α mRNA in type 2 diabetic rats

【Animal modeling】-Effect of camel milk on glucose and lipid metabolism and PPAR-γ, TNF-α mRNA in type 2 diabetic rats

To study the effect of camel milk (CM) on body weight, blood glucose, blood lipid, insulin, PPARγ and TNF-α gene expression in type 2 diabetic rats...

2022-07-21
【Animal Modeling】-Effect of subchronic exposure to diflubenzuron on the blood system of rats

【Animal Modeling】-Effect of subchronic exposure to diflubenzuron on the blood system of rats

Based on the study of the subchronic oral toxicity of diflubenzuron to rats, the effect on the blood system of rats after exposure was preliminarily discussed...

2022-07-21
【Animal modeling】-Effect of fibrinolytic system on podocyte injury in rats with membranous nephropathy

【Animal modeling】-Effect of fibrinolytic system on podocyte injury in rats with membranous nephropathy

To investigate the importance of early prevention of fibrinolytic disorder in preventing the progression of MN...

2022-07-21