【Animal Modeling】-Minocycline inhibits the hyperpolarization-activated current of glial neurons in the dorsal horn of rat spinal cord

To study the effect of minocycline on the hyperpolarization-activated current (Ih) of colloidal (SG) neurons in the spinal dorsal horn of rats...

2022-07-25

【Animal modeling】-Protective effect of emulsified fluorocarbon combined with ligustrazine on pulmonary ischemia-reperfusion injury in rats

To investigate the effect and mechanism of emulsified fluorocarbon combined with ligustrazine on pulmonary ischemia-reperfusion injury...

2022-07-25

【Animal Model】-Inhibitory effect of chloroquine on airway hyperresponsiveness in asthmatic mice

To investigate the effect of chloroquine on airway hyperresponsiveness in asthmatic mice and its possible mechanism...

2022-07-25

【Animal Modeling】-Effect of repetitive hypoxic preconditioning on liver injury induced by renal ischemia-reperfusion in rats

To investigate the effect of repetitive hypoxic preconditioning (RHP) on liver injury induced by renal ischemia-reperfusion injury (IRI) in rats and to preliminarily explore its mechanism...

2022-07-25

【Animal modeling】-The role of KA1 subreceptors in the death of hippocampal neurons induced by endoplasmic reticulum stress

To explore the role of up-regulated expression of KA1 sub-receptors in the death of hippocampal neurons induced by endoplasmic reticulum stress...

2022-07-25

【Animal Modeling】-Lentivirus-mediated shRNA targeting survivin gene inhibits the growth of endometrium in the abdominal cavity of nude mice

To study the effect of lentivirus-mediated survivin gene-specific short hairpin RNA (shRNA) on the growth of human endometrium in the peritoneal cavity of nude mice...

2022-07-25

【Animal Modeling】-Effect of alcohol exposure during pregnancy on basal rhythmic respiratory discharges in the medulla oblongata of neonatal rats

To investigate the effect of alcohol exposure during pregnancy on the basic rhythmic respiratory discharge in medullary bulb slices of offspring neonatal rats...

2022-07-25

【Animal Modeling】-miR-20b inhibits airway inflammation in asthmatic mice

To investigate the effect of miR-20b on airway inflammation in asthmatic mice...

2022-07-25

【Animal Modeling】-Regulatory T cell therapy for experimental mouse polymyositis and its mechanism

To investigate the therapeutic value and mechanism of CD4+ CD25+ Foxp3+ Treg cells in experimental autoimmune myositis (EAM) mice...

2022-07-25

【Animal modeling】-The treatment and mechanism of hemin on gestational hypertensive rats

To preliminarily explore the therapeutic effect and possible regulatory mechanism of heme oxygenase inducer hemin (Hemin) in rats with pregnancy-induced hypertension (HDCP)...

2022-07-25

【Animal modeling】- Oral human alpha interferon transforms Bifidobacterium to promote the proliferation and maturation of mouse lymphocytes

To investigate the regulatory effect of human alpha interferon (IFN-α) gene on the immune function of mice after oral administration of Bifidobacterium transformed...

2022-07-25

【Animal modeling】-Edaravone can reduce oxidative stress and delay myocardial fibrosis in rats

To investigate the effect of edaravone on reducing oxidative stress and anti-myocardial fibrosis...

2022-07-25

【Animal modeling】-Pathological changes of amyloidosis and cerebrovascular disease in Alzheimer's disease rats

To investigate the pathological changes of brain tissue of amyloidosis cerebrovascular lesions on the basis of establishing an experimental rat model of Alzheimer\\\'s disease...

2022-07-25

【Animal modeling】-Recombinant lentivirus-mediated LXRα RNA interference improves the function of rat fatty liver donor liver transplantation

To investigate the effect and mechanism of LXRα RNA interference (RNAi) in improving liver function in rats with fatty liver after liver transplantation...

2022-07-25

【Animal modeling】-Effect of acute incision pain on the expression of connexin Cx43 in the dorsal horn of spinal cord in rats

To observe the effect of acute incision pain on the expression of connexin43 (Cx43) in the dorsal horn of rat spinal cord...

2022-07-25

【Animal Modeling】-Determination of blood concentration of carbamazepine in rats after administration and its NMR metabolomics analysis

To analyze the effect of carbamazepine on the serum metabolome of rats after intragastric administration using nuclear magnetic resonance (NMR)-based metabolomics technology...

2022-07-25