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【Animal Modeling】-Effects of ethinylestradiol exposure before pregnancy on changes in glucose metabolism and the expression of genes related to hepatic glucose metabolism in offspring of rats

【Animal Modeling】-Effects of ethinylestradiol exposure before pregnancy on changes in glucose metabolism and the expression of genes related to hepatic glucose metabolism in offspring of rats

To use SD rats as a model to observe the effects of pre-pregnancy ethinyl estradiol exposure on the changes of glucose metabolism in offspring and the expression of genes related to glucose metabolism in the liver...

2022-07-21
【Animal Modeling】-Study on Oral Rehydration Salts Reducing Mortality in Rats with Lithium Chloride-Pilocarpine Status Convulsions

【Animal Modeling】-Study on Oral Rehydration Salts Reducing Mortality in Rats with Lithium Chloride-Pilocarpine Status Convulsions

To investigate a method for reducing mortality in a lithium chloride-pilocarpine-induced status convulsive model by gastric gavage with modified oral rehydration salts...

2022-07-21
【Animal modeling】-Effect of different intervention programs of simvastatin on bone mass in osteoporotic rats

【Animal modeling】-Effect of different intervention programs of simvastatin on bone mass in osteoporotic rats

To explore and compare the intervention effects of simvastatin on bone loss and bone quality decline in ovariectomized rats under different intervention programs...

2022-07-21
【Animal Modeling】-Effect of Polygoniside on the Expression Level of miR-214 and Liver Function in ApoE-/- Mice

【Animal Modeling】-Effect of Polygoniside on the Expression Level of miR-214 and Liver Function in ApoE-/- Mice

To study the effect of polydatin (PD) on liver miR-214 and liver function in ApoE-/- mice...

2022-07-21
【Animal Modeling】-Effects of Microbial Antioxidants on Sleep and Antioxidant Properties in Mice

【Animal Modeling】-Effects of Microbial Antioxidants on Sleep and Antioxidant Properties in Mice

To explore the effects of different doses of microbial-derived antioxidants on sleep and its antioxidant properties in mice...

2022-07-21
【Animal modeling】-Lithium chloride combined with calcium phosphate bone cement can promote the repair of tibial bone defect in rats

【Animal modeling】-Lithium chloride combined with calcium phosphate bone cement can promote the repair of tibial bone defect in rats

To observe the effect of calcium phosphate cement (CPC) and lithium chloride combined calcium phosphate cement (Li/CPC) on fracture healing in SD rats...

2022-07-21
【Animal modeling】-Comparison of repeated administration toxicity between doxorubicin liposome injection and doxorubicin injection in rats

【Animal modeling】-Comparison of repeated administration toxicity between doxorubicin liposome injection and doxorubicin injection in rats

To study the toxic effects of doxorubicin liposome injection and doxorubicin injection by continuous intravenous injection on rats and compare the similarities and differences of toxicity...

2022-07-21
【Animal modeling】-Effect of bee venom on TrkA and TRPV1 in dorsal root ganglia of rats with collagen-induced arthritis inflammatory pain

【Animal modeling】-Effect of bee venom on TrkA and TRPV1 in dorsal root ganglia of rats with collagen-induced arthritis inflammatory pain

To investigate the effect of bee venom on TrkA and TRPV1 pain signaling molecules in collagen-induced arthritis rats...

2022-07-21
【Animal Modeling】-Effects of chronic corticosterone treatment on learning and memory and synapse-related proteins in mice

【Animal Modeling】-Effects of chronic corticosterone treatment on learning and memory and synapse-related proteins in mice

To establish a drinking method, chronically administer corticosterone, and observe the effects of corticosterone on learning and memory and synapse-related proteins...

2022-07-21
【Animal modeling】-The phenotypic characteristics of lymphocytes in HBV transgenic mice and the effect of interferon α on them

【Animal modeling】-The phenotypic characteristics of lymphocytes in HBV transgenic mice and the effect of interferon α on them

To investigate the phenotypic characteristics of lymphocytes in hepatitis B virus (HBV) transgenic mice and the effect of interferon α on virological indexes and immune cell phenotypes...

2022-07-21
【Animal Modeling】-Changes of Blood Indexes in Long-term Toxicity Experiment of Niaotongkake Naiqi Tablets in Rats

【Animal Modeling】-Changes of Blood Indexes in Long-term Toxicity Experiment of Niaotongkake Naiqi Tablets in Rats

To investigate the changes of hematological indexes in the long-term toxicity test of Niaotongkake Naiqi tablets in rats...

2022-07-20
【Animal modeling】-Effect of hypoxia on the expressions of drug transporters MDR1 and MRP2 in rats

【Animal modeling】-Effect of hypoxia on the expressions of drug transporters MDR1 and MRP2 in rats

To study the effects of simulated rapid altitude hypoxia on some physiological indexes and the expressions of MDR1 and MRP2 efflux drug transporters in the small intestine, liver and kidney of rats, and to preliminarily explore the effect of high alt...

2022-07-20
【Animal Modeling】-Effects of chronic arsenic exposure on brain and serum metabolomics in mice

【Animal Modeling】-Effects of chronic arsenic exposure on brain and serum metabolomics in mice

To observe the effects of chronic arsenic exposure on the metabolomics of mouse cortex and serum, and to explore its neurotoxicity mechanism...

2022-07-20
【Animal Modeling】-The relationship between sex differences in blood pressure and sodium channels in mouse kidneys

【Animal Modeling】-The relationship between sex differences in blood pressure and sodium channels in mouse kidneys

To study blood pressure, renal urinary sodium excretion and related renal sodium channels and signaling pathways in male and female mice, and to preliminarily explore the relationship between sex differences in blood pressure and renal sodium channel...

2022-07-20
【Animal modeling】-Protective effect of liraglutide on stress-stressed chronic heart failure in rats

【Animal modeling】-Protective effect of liraglutide on stress-stressed chronic heart failure in rats

To study the effect and mechanism of liraglutide on cardiac function in pressure-stressed chronic heart failure rats...

2022-07-20
【Animal Modeling】-Study on vascular calcification and expression of vascular wall osteopontin and osteocalcin in aged rats

【Animal Modeling】-Study on vascular calcification and expression of vascular wall osteopontin and osteocalcin in aged rats

To study the occurrence of vascular calcification in aged rats, and the changes of osteopontin and osteocalcin expression in the arterial vessel wall of aged rats...

2022-07-20