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【Animal modeling】-Anti-atherosclerosis and cardioprotective effects of perilla seed extract in ApoE-/- mice

【Animal modeling】-Anti-atherosclerosis and cardioprotective effects of perilla seed extract in ApoE-/- mice

The effect and molecular mechanism of perilla seed oily extract (PSO) on reducing plaque formation and cardioprotection in ApoE-/- mice...

2022-01-11
【Animal Modeling】-Biosafety and Data Quality Considerations for Animal Experiments on Highly Infectious Drugs in ABSL-3 Facility

【Animal Modeling】-Biosafety and Data Quality Considerations for Animal Experiments on Highly Infectious Drugs in ABSL-3 Facility

Animal models are the key to the study of serious infectious diseases, and are of great significance to determine the pathogenesis of the disease and develop vaccines and drugs...

2022-01-11
【Animal modeling】-Protective effect of aerobic exercise combined with paeonol PLGA nanoparticles on obese rats with hyperlipidemia

【Animal modeling】-Protective effect of aerobic exercise combined with paeonol PLGA nanoparticles on obese rats with hyperlipidemia

To investigate the effect of aerobic exercise combined with paeonol PLGA nanoparticles on blood biochemistry and lipid metabolism in obese rats with hyperlipidemia...

2022-01-11
【Animal modeling】-Effect of busulfan on peripheral blood cells and bone marrow cells of type 2 diabetic KKAy mice

【Animal modeling】-Effect of busulfan on peripheral blood cells and bone marrow cells of type 2 diabetic KKAy mice

To observe the damage effect of busulfan on the hematopoietic system function of type 2 diabetes model KK/upj-Ay/J (KKAy) mice and compare with control C57BL/6J (B6) mice...

2022-01-11
【Animal Model】-Effects of nicotine on changes in pain threshold plasticity and cardioprotection in rats with myocardial infarction

【Animal Model】-Effects of nicotine on changes in pain threshold plasticity and cardioprotection in rats with myocardial infarction

To observe the plasticity of pain threshold in rats with myocardial infarction, and to explore the effect of nicotine on visceral pain and whether it has a protective effect on ischemic myocardium...

2022-01-11
【Animal modeling】-The dose-response relationship of Xingnaojing injection in the treatment of traumatic brain coma in Beagle dogs

【Animal modeling】-The dose-response relationship of Xingnaojing injection in the treatment of traumatic brain coma in Beagle dogs

To observe the effect of Xingnaojing injection on the dose-response relationship of coma in Beagle dogs...

2022-01-11
【Animal Modeling】-Effects of Different Exercise Mode Interventions on Emotional Behavior in Aggressive Rats

【Animal Modeling】-Effects of Different Exercise Mode Interventions on Emotional Behavior in Aggressive Rats

To investigate the effects of different exercise interventions on emotional behavior of aggressive rats...

2022-01-11
【Animal Modeling】-Effect of hypoxia training on Ghrelin-GHSR pathway in obese mice

【Animal Modeling】-Effect of hypoxia training on Ghrelin-GHSR pathway in obese mice

To apply hypoxic training to obese mice and observe the changes of GHSR levels in gastric tissue and hypothalamus, so as to explore whether hypoxic training affects the Ghrelin-GHSR pathway to improve obesity...

2022-01-11
【Animal modeling】-Intervention effect of electroacupuncture on NF-κBp65 protein in the spinal dorsal horn of rats with diabetic neuralgia

【Animal modeling】-Intervention effect of electroacupuncture on NF-κBp65 protein in the spinal dorsal horn of rats with diabetic neuralgia

To observe the intervention effect of electroacupuncture on the nuclear transcription factor κB-p65 protein in the spinal dorsal horn of rats with diabetic neuralgia, so as to explore the partial analgesic mechanism of electroacupuncture in diabetic ...

2022-01-11
【Animal Modeling】-Antioxidative protective effect of terrein on CCl4-induced chronic liver injury in mice

【Animal Modeling】-Antioxidative protective effect of terrein on CCl4-induced chronic liver injury in mice

To investigate the antioxidant protective effect of teretin on CCl4-induced chronic liver injury in mice...

2022-01-11
【Animal modeling】-The regulatory effect of ferulic acid on hepatic steatosis and intestinal flora in hyperlipidemia mice

【Animal modeling】-The regulatory effect of ferulic acid on hepatic steatosis and intestinal flora in hyperlipidemia mice

To investigate the regulatory effect of ferulic acid on hepatic steatosis and intestinal flora in hyperlipidemia mice...

2022-01-11
【Animal modeling】-Effect of hydroxychloroquine on spleen lymphocytes in lupus mice

【Animal modeling】-Effect of hydroxychloroquine on spleen lymphocytes in lupus mice

To observe the effect of hydroxychloroquine on the distribution of lymphocytes in peripheral immune organs (spleen) of mice with systemic lupus erythematosus (TC mice)...

2022-01-11
【Animal Modeling】-Galactosamine-induced liver failure model

【Animal Modeling】-Galactosamine-induced liver failure model

Replication method Adult rats are fasted for 12 hours and injected intraperitoneally with D-galactosamine (D-Gal) at a body weight of 1.2 to 1.8 g/kg...

2022-01-10
【Disease Animal Model】-Acute Myeloid Leukemia Animal Model

【Disease Animal Model】-Acute Myeloid Leukemia Animal Model

he human acute myeloid leukemia cell line HL-60 is allotransplanted into SCID mice with T and B lymphocyte function combined with immunodeficiency to establish a SCID mouse model with human hematopoietic function. This is the current study of humans...

2022-01-10
[Animal modeling] The effect of thrombolysis within 6 hours on acute cerebral infarction in a rat model of ischemic stroke with middle cerebral artery embolism

[Animal modeling] The effect of thrombolysis within 6 hours on acute cerebral infarction in a rat model of ischemic stroke with middle cerebral artery embolism

Stroke is one of the most common diseases affecting human health, the second leading cause of death and the first leading cause of disability in China...

2022-01-10
【Animal Modeling】-Study on the characteristics of spontaneous hindlimb paralysis in hyperlipidemia-susceptible (WSHc) rats

【Animal Modeling】-Study on the characteristics of spontaneous hindlimb paralysis in hyperlipidemia-susceptible (WSHc) rats

Observe the etiology and pathological characteristics of hyperlipidemia (WSHc) rats with spontaneous hindlimb paralysis, study the etiology in advance, and explore its application and scientific research value...

2022-01-10