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【Animal Modeling】-Lactobacillus rhamnosus culture supernatant prevents Escherichia coli meningitis by inhibiting NF-κB pathway

【Animal Modeling】-Lactobacillus rhamnosus culture supernatant prevents Escherichia coli meningitis by inhibiting NF-κB pathway

To investigate whether Lactobacillus rhamnosus supernatant (LGG-CM) can block bacterial meningitis caused by E. coli K1 strain by inhibiting NF-κB pathway in vitro...

2022-05-31
【Animal modeling】-Effect of low selenium diet on the expressions of CD163, CD206 and CCR7 in the liver and kidney of rats

【Animal modeling】-Effect of low selenium diet on the expressions of CD163, CD206 and CCR7 in the liver and kidney of rats

To investigate the effect of low selenium diet on liver and kidney in rats, and the role of macrophage polarization to M1 and M2 in liver and kidney fibrosis...

2022-05-31
【Animal modeling】-Observation of the anesthesia effect of compound anesthesia on Wuzhishan miniature pigs for up to 8 hours

【Animal modeling】-Observation of the anesthesia effect of compound anesthesia on Wuzhishan miniature pigs for up to 8 hours

To observe the general anesthesia effect of ketamine?Sumianxin II and midazolam mixture for induction of anesthesia, and ketamine and propofol to maintain anesthesia on Wuzhishan miniature pigs for up to 8 hours?...

2022-05-31
【Animal Modeling】-Effect of Trichinella spiralis and its worm-derived protein on cecal ligation and puncture-induced sepsis in mice

【Animal Modeling】-Effect of Trichinella spiralis and its worm-derived protein on cecal ligation and puncture-induced sepsis in mice

To observe the effect of Trichinella spiralis and its parasite-derived protein on cecal ligation and puncture (CLP)-induced sepsis in mice...

2022-05-31
【Animal Modeling】-Comparative Analysis of Skin Wound Healing in BALB/c Mutant Curly-haired Mice

【Animal Modeling】-Comparative Analysis of Skin Wound Healing in BALB/c Mutant Curly-haired Mice

To investigate the differences between BALB/c mutant curly hair mice and control BALB/c mice in the natural healing process of skin injury...

2022-05-31
【Animal Modeling】-SOD activity of diabetic rats and the effect of antioxidant treatment on the antioxidant status of the body

【Animal Modeling】-SOD activity of diabetic rats and the effect of antioxidant treatment on the antioxidant status of the body

To explore the changes of SOD activity and protein expression in main organs of diabetic rats, and to observe the effect of the antioxidant N-acetylcysteine on the antioxidant status of the body after short-term treatment (4 weeks)...

2022-05-31
【Animal modeling】-Effect of Oct4 and Cdx2 on the differentiation of bovine embryo inner cell mass and trophectoderm

【Animal modeling】-Effect of Oct4 and Cdx2 on the differentiation of bovine embryo inner cell mass and trophectoderm

To investigate the effects of Oct4 and Cdx2 knockdown on the expression of genes related to the differentiation of bovine ICM and TE, and to explain the roles of Oct4 and Cdx2 in the early development of bovine embryos...

2022-05-31
【Animal Modeling】-Effects of Unpredictable Stress Stimulation on the Immunity and Microflora of the Gastrointestinal Tract in Rats

【Animal Modeling】-Effects of Unpredictable Stress Stimulation on the Immunity and Microflora of the Gastrointestinal Tract in Rats

To analyze the effects of unpredictable stress on the gastrointestinal immune system and microbial population by observing the rats after 9 days of unpredictable stress stimulation, so as to provide reference for the study of chronic stress on gastro...

2022-05-31
【Animal Modeling】-Corticosterone-induced Depression in Mice Associated with Learning and Memory Impairment

【Animal Modeling】-Corticosterone-induced Depression in Mice Associated with Learning and Memory Impairment

To study the effects of chronic subcutaneous injection of corticosterone on depressive-like behaviors with learning and memory impairment in mice...

2022-05-31
【Animal modeling】-The acute toxicity of CKLF1-C19 to Kunming mice

【Animal modeling】-The acute toxicity of CKLF1-C19 to Kunming mice

To study the acute toxicity of the polypeptide CKLF1-C19 of chemokine-like factor 1 (CKLF1) on Kunming mice...

2022-05-31
【Animal modeling】-Isolation, culture and identification of goat alveolar macrophages

【Animal modeling】-Isolation, culture and identification of goat alveolar macrophages

To establish a high-purity method for isolating and culturing alveolar macrophages to provide materials for studying the biological characteristics of macrophages and the survival mechanism of intracellular parasites...

2022-05-31
【Animal modeling】-Optimization of SD rat skin chemical hair removal parameters based on D-optimal design

【Animal modeling】-Optimization of SD rat skin chemical hair removal parameters based on D-optimal design

To study the depilation parameters of SD rat skin, and to provide basic experimental conditions for establishing skin photoaging animal model...

2022-05-31
【Animal modeling】-radioprotective effect of diallyl disulfide on mouse spermatogenic cells

【Animal modeling】-radioprotective effect of diallyl disulfide on mouse spermatogenic cells

To study the radioprotective effect of diallyl disulfide (DADS) on mouse spermatogenic cells...

2022-05-27
【Animal modeling】-Protective effect of Guanxinning tablet on myocardial ischemia-reperfusion injury in rats

【Animal modeling】-Protective effect of Guanxinning tablet on myocardial ischemia-reperfusion injury in rats

To observe the effect of Guanxinning Tablets (GXNT) on myocardial infarction and cardiac autonomic function in rats with myocardial ischemia-reperfusion injury (MI/RI)...

2022-05-27
【Animal Modeling】-Transcranial ultrasound perfusion imaging performance and safety evaluation in rats after skull thinning

【Animal Modeling】-Transcranial ultrasound perfusion imaging performance and safety evaluation in rats after skull thinning

To observe and quantitatively evaluate the performance of right brain transcranial ultrasound perfusion imaging by thinning the local skull of SD rats to improve the acoustic window, and to preliminarily evaluate the effect of bone grinding and trans...

2022-05-27
【Animal Modeling】-A comparative study of in situ liver cancer dynamic imaging and pathology in nude mice

【Animal Modeling】-A comparative study of in situ liver cancer dynamic imaging and pathology in nude mice

To dynamically monitor tumor growth in nude mice after orthotopic liver cancer modeling and to compare it with pathology, so as to determine the appropriate period of intervention therapy...

2022-05-27