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【Animal modeling】-Microsatellite DNA analysis of the genetic status of 24 domestic inbred strains of mice

【Animal modeling】-Microsatellite DNA analysis of the genetic status of 24 domestic inbred strains of mice

To analyze the genetic status of 24 domestic inbred mice using microsatellite loci...

2022-05-19
【Animal modeling】-Changes of IL-6, SOD and MDA in the lung tissue of rats with acute pulmonary edema

【Animal modeling】-Changes of IL-6, SOD and MDA in the lung tissue of rats with acute pulmonary edema

To investigate the changes and significance of malondialdehyde, superoxide dismutase and interleukin-6 in lung tissue of acute hypoxia-induced acute pulmonary edema in rats...

2022-05-19
【Animal modeling】-Effect of PLCζ on oocyte fertilization and embryonic development after injection of mouse round spermatids

【Animal modeling】-Effect of PLCζ on oocyte fertilization and embryonic development after injection of mouse round spermatids

To investigate the feasibility of PLCζ as an activator and its effect on oocyte fertilization and embryonic development after ROSI...

2022-05-19
【Animal Modeling】-Discussion on the Sequence Scheme of Reducing Image Respiration and Heartbeat Artifacts in In vivo Thoracic Scanning of Rats

【Animal Modeling】-Discussion on the Sequence Scheme of Reducing Image Respiration and Heartbeat Artifacts in In vivo Thoracic Scanning of Rats

To develop a sequence that reduces image breathing and heartbeat artifacts in 256-slice spiral CT rat in vivo chest CT scans...

2022-05-19
【Animal Modeling】-Exploration on the Application of Automatic Control Technology System of Laboratory Animal Barrier Facility System

【Animal Modeling】-Exploration on the Application of Automatic Control Technology System of Laboratory Animal Barrier Facility System

To realize the stable operation of the experimental animal barrier system, research and explore the automatic control technology of the experimental animal barrier system...

2022-05-19
【Animal modeling】-The regulatory effect of Quqi powder on telomerase activity in precancerous lesions of liver cancer

【Animal modeling】-The regulatory effect of Quqi powder on telomerase activity in precancerous lesions of liver cancer

To investigate the role of telomerase in the formation and development of precancerous lesions of hepatocellular carcinoma and the regulation mechanism of the prescription mistletoe powder (HQS) and the monarch drug mistletoe on its activity...

2022-05-18
【Animal modeling】-plasma lipidomic characteristics of spontaneously obese rhesus monkeys

【Animal modeling】-plasma lipidomic characteristics of spontaneously obese rhesus monkeys

The increasing prevalence of obesity is becoming a medical and public health concern as obesity is closely associated with metabolic abnormalities including hyperlipidemia, nonalcoholic fatty liver disease (NAFLD), type 2 diabetes (T2D) and cardiovas...

2022-05-18
【Animal modeling】-Exploration of the protective effect of bifidobacteria on liver function in rats with chronic alcoholic liver injury

【Animal modeling】-Exploration of the protective effect of bifidobacteria on liver function in rats with chronic alcoholic liver injury

To investigate the protective or influence of bifidobacteria on liver function in rats with chronic alcoholic liver injury, and to explore its mechanism preliminarily...

2022-05-18
【Animal Modeling】-Efficacy and safety of electroacupuncture combined with methylprednisolone on intervertebral disc prolapse in rats

【Animal Modeling】-Efficacy and safety of electroacupuncture combined with methylprednisolone on intervertebral disc prolapse in rats

To observe the effects of electroacupuncture combined with methylprednisolone and electroacupuncture or methylprednisolone alone on limb motor function and neuronal Nissl bodies in a rat model 24 hours after intervertebral disc prolapse, and to provi...

2022-05-18
【Animal modeling】-Construction of MiR-31 transgenic mice and its expression in tissues and organs

【Animal modeling】-Construction of MiR-31 transgenic mice and its expression in tissues and organs

To construct stably overexpressed miR-31 transgenic mice, to detect the expression changes of miR-31 in major tissues and organs, and to provide qualified tool mice for the application of miR-31 overexpression in vivo...

2022-05-18
【Animal Modeling】-Effect of Mac-1 gene deletion on the growth of melanoma

【Animal Modeling】-Effect of Mac-1 gene deletion on the growth of melanoma

To investigate the effect of Mac-1 deletion on melanoma tumor growth...

2022-05-18
【Animal Modeling】-Relevant mechanism of hypertonic saline protecting blood-brain barrier and reducing cerebral edema in rats with cerebral hemorrhage

【Animal Modeling】-Relevant mechanism of hypertonic saline protecting blood-brain barrier and reducing cerebral edema in rats with cerebral hemorrhage

To investigate the related mechanism of hypertonic saline treatment in reducing cerebral edema in rats with cerebral hemorrhage...

2022-05-18
【Animal modeling】-Effect of Bcl-2 inhibitor on astragalus injection on reducing the apoptosis of hippocampal neurons in rats with hypoxia and hypoglycemia/reoxygenation and reglycemia

【Animal modeling】-Effect of Bcl-2 inhibitor on astragalus injection on reducing the apoptosis of hippocampal neurons in rats with hypoxia and hypoglycemia/reoxygenation and reglycemia

To investigate the effect of astragalus injection (AI) on the apoptosis of hippocampal neurons in hypoxia-hypoglycemia/reoxygenation and reglycemia (H/R) rats under the action of Bcl-2 inhibitor (TW-37)...

2022-05-18
【Animal modeling】-Effect of acute exercise on the expression of miRNA-30a in rat myocardium

【Animal modeling】-Effect of acute exercise on the expression of miRNA-30a in rat myocardium

To study the effect of acute exercise on myocardial miRNA-30a and the expression of autophagy-related genes in rats, and to explore the regulatory mechanism of miRNA-30a on myocardial autophagy activity in different recovery periods after exercise...

2022-05-18
【Animal Modeling】-partial simple epilepsy model in rats

【Animal Modeling】-partial simple epilepsy model in rats

1. Model animals: male or female rats weighing 200-300 g: drugs: pentobarbital, FeCl3 solution, equipment: rat stereotaxic device....

2022-05-18
【Animal modeling】-Guanxinning tablet inhibits myocardial cell apoptosis in chronic heart failure mice through PI3K/AKT signaling pathway

【Animal modeling】-Guanxinning tablet inhibits myocardial cell apoptosis in chronic heart failure mice through PI3K/AKT signaling pathway

To observe the therapeutic effect of Guanxinning Tablets on chronic heart failure (CHF) mice, and to explore its action pathway from myocardial cell apoptosis and related cell signaling pathways, so as to provide experimental basis for the clinical a...

2022-05-17