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Improvement and evaluation of the method of establishing necrotizing enterocolitis in neonatal rats

Improvement and evaluation of the method of establishing necrotizing enterocolitis in neonatal rats

By improving and comparing the methods for establishing necrotizing enterocolitis animal models commonly used at home and abroad, a simple and effective NEC modeling method is clarified...

2020-12-09
Experimental Study on the Model of Focal Cerebral Ischemia in Balb/c Mice Made by Electrocoagulation

Experimental Study on the Model of Focal Cerebral Ischemia in Balb/c Mice Made by Electrocoagulation

Observe the feasibility of electrocoagulation method to coagulate the middle cerebral artery in mice, causing middle cerebral artery occlusion, and establishing the feasibility of cerebral ischemia model in mice...

2020-12-09
Construction of a Systemic Model of Parkinson\'s Disease Cynomolgus Monkeys and Dynamic Evaluation of In Vivo Clinical Process

Construction of a Systemic Model of Parkinson's Disease Cynomolgus Monkeys and Dynamic Evaluation of In Vivo Clinical Process

  Applying behavioral and molecular imaging methods to dynamically evaluate the clinical change characteristics of the cynomolgus monkey model of Parkinson\'s disease in vivo, providing a stable and effective PD primate model for pre-clinical studies...

2020-12-09
Analysis of the preparation and comparison of animal models of facial paralysis

Analysis of the preparation and comparison of animal models of facial paralysis

Search the related literature of different models of facial paralysis animals, analyze the advantages and disadvantages of various model preparation methods, and explore the preparation methods suitable for different research types, so as to provide ...

2020-12-09
Experimental study of a mouse model of slow transit constipation induced by loperamide hydrochloride

Experimental study of a mouse model of slow transit constipation induced by loperamide hydrochloride

Through loperamide hydrochloride-induced slow transit constipation mouse model, compare the differences between the models induced by different doses and different administration times, and explore the establishment of a stable loperamide hydrochlori...

2020-12-09
Long-term depression mouse model establishment and behavioral and neuropathological characteristics observation

Long-term depression mouse model establishment and behavioral and neuropathological characteristics observation

Construct a new type of long-term depression model mouse and compare the advantages and disadvantages of this type of mouse with common depression mouse models...

2020-12-09
Comparative study on establishing mouse models of allergic conjunctivitis under different conditions

Comparative study on establishing mouse models of allergic conjunctivitis under different conditions

Establish allergic conjunctivitis mouse models under different antigens, different excitation pathways, and different ages of mice. By comparing the immune response status and screening the best sensitization conditions, it is the establishment of al...

2020-12-09
The establishment of a new type of hyperlipidemia susceptible (WSHc) rat model of non-alcoholic fatty liver disease and the study of its pathological characteristics

The establishment of a new type of hyperlipidemia susceptible (WSHc) rat model of non-alcoholic fatty liver disease and the study of its pathological characteristics

Use a new type of hyperlipidemia susceptible rat to establish a non-alcoholic fatty liver disease model, observe the changes in blood biochemical indicators and pathological characteristics, explore its application and scientific research value, and ...

2020-12-09
Construction of a nude mouse model of clear cell renal carcinoma and study on the sensitivity of targeted drugs

Construction of a nude mouse model of clear cell renal carcinoma and study on the sensitivity of targeted drugs

Use patient-derived cells (PDCs) of clear cell renal cancer cells to establish tumor animal models, detect the sensitivity of ccRCC PDCs to molecular targeted drugs, and provide theoretical and experimental basis for clinical diagnosis and treatment...

2020-12-09
Evaluation and research progress of common behavioral paradigms of mother-infant separation models

Evaluation and research progress of common behavioral paradigms of mother-infant separation models

As an important way of early social deprivation, mother-infant separation has always been a classic animal model for studying the neurobiological mechanism of the adverse effects of early life stress on the individual\'s physiology and psychology...

2020-12-09
Preparation of a mouse model of alcoholic cardiomyopathy by feeding liquid feed

Preparation of a mouse model of alcoholic cardiomyopathy by feeding liquid feed

Using liquid feed to establish a mouse model of alcoholic cardiomyopathy, providing a good animal model for the study of the mechanism of alcoholic cardiomyopathy...

2020-12-09
SARS-CoV-2 infection mouse model and its pathogenesis

SARS-CoV-2 infection mouse model and its pathogenesis

Previous studies have shown that transgenic mice expressing human ACE2 are highly susceptible to SARS-CoV infection...

2020-12-09
The Making of Rabbit Model of Myocardial Iron Overload and the Study of Iron Deposition

The Making of Rabbit Model of Myocardial Iron Overload and the Study of Iron Deposition

To explore the method of making myocardial iron deposition animal model and the relationship between the iron deposition law of the heart and liver...

2020-12-09
Study on the regulatory effect and mechanism of silencing miRNA-16 on the immune function of pulmonary tuberculosis model mice

Study on the regulatory effect and mechanism of silencing miRNA-16 on the immune function of pulmonary tuberculosis model mice

To study the regulatory effect and mechanism of silencing miR-16 on the immune function of pulmonary tuberculosis model mice...

2020-12-09
Establishment and evaluation of rat model of chronic obstructive pulmonary disease

Establishment and evaluation of rat model of chronic obstructive pulmonary disease

A rat model of chronic obstructive pulmonary disease (COPD) was constructed by smoking method, protease instillation and a combination of the two methods, and the effect of the model was evaluated from the aspects of inflammation, imaging, and pathol...

2020-12-09
Establishment and comparison of positive models of fertility and early embryonic developmental toxicity in female rats

Establishment and comparison of positive models of fertility and early embryonic developmental toxicity in female rats

Compare the changes in reproduction and development indexes of female rats after giving different doses and times of cyclophosphamide before mating, and establish a standardized positive control model for fertility and early embryonic developmental t...

2020-12-09