miR-199a aggravates cardiomyocyte damage by activating NF-κB signaling pathway in primary rat cardiomyocytes induced by LPS

Explore the role of miR-199a in LPS-induced primary rat cardiomyocytes...

2020-12-10

IVC cage replacement standard operating procedures and the risk of transmission of mouse virus pathogens

Study the standard operating procedures for cage replacement of independent ventilated cages and the risk of virus infection in mice reared with IVC (individual ventilated cage, IVC) equipment in laboratory animal negative pressure barrier facilities...

2020-12-10

Based on the systematic review of pathomorphology to explore the difference between porcine coronary artery balloon injury and atherosclerosis

Through a systematic review to analyze the histomorphological characteristics of porcine coronary artery balloon injury lesions, and compare with the histomorphology of human atherosclerotic plaques, provide a basis for the rational application of th...

2020-12-10

Determination of blood physiological and biochemical indexes in guinea pigs

Measure the growth body mass, blood physiology and biochemical indexes of SPF grade Hartley guinea pig core group, and compare it with the clean grade guinea pig indexes...

2020-12-10

The relationship between serum TF, TM, vWF levels in SD rats and the formation of CRT

By establishing a rat external jugular vein catheter-related thrombosis (CRT) model, observing the formation of rat CRT, and detecting tissue factor (TF), thrombomodulin (TM) and von Willebrand factor in rat serum (vWF) content, study its relationshi...

2020-12-10

Establishment of RT-qPCR method for detecting the transcription level of xanthine dehydrogenase/oxidase gene in Wistar rats

Establish a real-time fluorescence quantitative (RT-qPCR) method to detect the transcription level of the xanthine hydrogenase/oxidase (XDH/XO) gene in Wistar rats in order to quantitatively detect the XDH/XO gene at the transcription level...

2020-12-10

A simple and convenient new method for extracting mouse cerebrospinal fluid

Establish a simple and easy method for extracting mouse cerebrospinal fluid, low materials, high survival rate and success rate, and provide reference for related research on mouse cerebrospinal fluid...

2020-12-10

Breeding and genotype identification of type I interferon receptor (Ifnar) knockout mice

Analyze the breeding and identification and adjustment methods of Ifnar gene knockout mice to provide an ideal animal model for a variety of virus research...

2020-12-10

Discussion on the Technique of Frozen Section of Different Tissues in Mice

Explore the methods and techniques of making frozen sections of different tissues in experimental animals and mice, improve the quality of frozen sections, and better serve the non-clinical safety evaluation of monoclonal antibodies...

2020-12-10

Phenomorphological analysis of GFP nude mouse skull cells cultured in vitro

The green fluorescent protein gene inbred nude mice (GFP nude mice) established in this study have played an important role in tracing and studying the microenvironment of gliomas, but they are important for the treatment of bone resorption complicat...

2020-12-10

Investigation of new coronavirus infection in laboratory animals

Investigation of new coronavirus infection in laboratory animals...

2020-12-10

Establishment of Fluorescence Quantitative PCR Detection Method for Common Mycoplasma in Laboratory Animals

Establish a fluorescent quantitative PCR method that can detect common mycoplasma in laboratory animals...

2020-12-10

Stable expression of human coagulation factor IX gene in mouse adipose stem cells

Transfect the recombinant adenovirus carrying the human coagulation factor IX (hFIX) gene (F9) into C57BL/6 mouse adipose-derived stem cell (ADSC), after subculture, observe whether F9 is in the ADSC Stable expression to explore whether ADSC can be u...

2020-12-10

A comparative study of the effects of different factors on the establishment of a rat model of myocardial hypertrophy induced by isoprenaline

To observe and compare the effects of different genders and injection doses on the establishment of a rat model of myocardial hypertrophy induced by isoproterenol (ISO)...

2020-12-10

Establishment of lung metastasis and postoperative recurrence model in mice injected by bone marrow

Establish models of lung metastasis and postoperative recurrence via bone marrow injection, reveal the superiority and feasibility of the model constructed by bone marrow injection, and provide a new research basis for studying lung metastasis of mal...

2020-12-10

Establishment of a rat model of coronary heart disease with combination of Qi deficiency and blood stasis syndrome

Through the analysis of coronary heart disease syndrome of Qi deficiency and blood stasis syndrome combined with pathology, etiology, compound model tongue manifestations and the relationship with prostacyclin (PGI2) and thromboxane A2 (thromboxane A...

2020-12-10