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Animal experiment: Safety pharmacology and subchronic toxicity evaluation of Jinqing granules

Animal experiment: Safety pharmacology and subchronic toxicity evaluation of Jinqing granules

There are about 12,000 kinds of Chinese medicines in clinical use, most of which are herbal medicine. The origin and development of Chinese medicine are the practical experience and medical practice of working people....

2020-11-17
Animal experiments: Studies have found that mice that lose their sense of smell after ingesting high-fat foods do not increase significantly

Animal experiments: Studies have found that mice that lose their sense of smell after ingesting high-fat foods do not increase significantly

The aroma of food is a key factor in inducing appetite. According to foreign media reports, a study now found that mice that temporarily lose their sense of smell while ingesting the same food are much lighter than control mice with normal sense of s...

2020-11-17
Therapeutic effect of nutritional supplements on retinopathy of diabetic rats

Therapeutic effect of nutritional supplements on retinopathy of diabetic rats

Retinopathy remains one of the most devastating complications of diabetes. Although basic science and clinical research have made significant progress to understand the complex pathophysiological mechanism of this blinding disease, the exact mechanis...

2020-11-17
Comparison of acute postoperative response and postoperative stress between video-assisted thoracoscopy and thoracotomy for small pigs

Comparison of acute postoperative response and postoperative stress between video-assisted thoracoscopy and thoracotomy for small pigs

Video-assisted thoracoscopic surgery (VATS) has been used as a diagnostic and therapeutic platform to perform various thoracic surgery operations...

2020-11-17
Study on the Effect and Mechanism of miR-221 in H2O2 Induced Cardiomyocyte Injury in Rats

Study on the Effect and Mechanism of miR-221 in H2O2 Induced Cardiomyocyte Injury in Rats

To explore the role and mechanism of miR-221 in the damage of rat cardiomyocytes (H9c2) induced by hydrogen peroxide (H2O2)...

2020-11-17
Effect of paclitaxel on the expression of CD28, CTLA-4 and BAFF in rats with experimental autoimmune encephalomyelitis

Effect of paclitaxel on the expression of CD28, CTLA-4 and BAFF in rats with experimental autoimmune encephalomyelitis

To explore the effect of paclitaxel on the expression of CD28 and CTLA-4 in the brain tissue of experimental autoimmune encephalomyelitis (EAE) rats and the content of B cell stimulating factor (BAFF) in the supernatant of spleen tissue and its signi...

2020-11-17
Effect of intrauterine injection of absolute ethanol on the estrous cycle of mice

Effect of intrauterine injection of absolute ethanol on the estrous cycle of mice

To investigate the effect of intrauterine injection of absolute ethanol on the estrous cycle of mice...

2020-11-17
Mouse experiments revealed that low-dose penicillin may induce long-term behavioral changes in offspring

Mouse experiments revealed that low-dose penicillin may induce long-term behavioral changes in offspring

In a research report published in the international journal Nature Communications, researchers from McMaster University and other institutions completed a landmark study. They found that low-dose penicillin was provided to pregnant mice clinically Ma...

2020-11-16
Changes of blood biochemical indexes in rats with chronic alcoholic liver injury after transplantation of human amniotic membrane mesenchymal stem cells

Changes of blood biochemical indexes in rats with chronic alcoholic liver injury after transplantation of human amniotic membrane mesenchymal stem cells

Studies have shown that human amniotic mesenchymal stem cells (hAMSCs) have a variety of differentiation and proliferation functions, which can induce differentiation into liver-like cells, thereby having a certain repair effect on liver injury...

2020-11-16
Pharmacokinetic study of multi-dose administration of granisetron hydrochloride transdermal patch in Beagle dogs

Pharmacokinetic study of multi-dose administration of granisetron hydrochloride transdermal patch in Beagle dogs

Establish a blood concentration determination method for granisetron hydrochloride transdermal patch in Beagle dogs. Through multi-dose administration in Beagle dogs, reveal the pharmacokinetics of granisetron hydrochloride transdermal patch in Beagl...

2020-11-16
The effect of DS-1226 on the depressive behavior of mice induced by chronic sleep disturbance

The effect of DS-1226 on the depressive behavior of mice induced by chronic sleep disturbance

To study the antidepressant effect of ginsenoside hydrolysate DS-1226 on chronic sleep disturbance mice, and provide scientific basis for the development of antidepressant drugs...

2020-11-16
Study on the mechanism of trace element strontium to improve non-alcoholic fatty liver in rats

Study on the mechanism of trace element strontium to improve non-alcoholic fatty liver in rats

To explore the mechanism of trace element strontium to improve non-alcoholic fatty liver in rats...

2020-11-16
Effects of neural stem cell-specific LSD1 gene knockout on mood and memory in mice

Effects of neural stem cell-specific LSD1 gene knockout on mood and memory in mice

After conditionally knocking out the LSD1 gene of mouse neural stem cells, the neurobiological function of LSD1 was revealed by observing the proliferation of mouse nerve cells and the behavior of mice...

2020-11-16
Effects of androgen deficiency on visceral fat accumulation and inflammatory gene expression in miniature pigs under high-fat environment

Effects of androgen deficiency on visceral fat accumulation and inflammatory gene expression in miniature pigs under high-fat environment

To explore the effects of androgen deficiency in high-fat environment on visceral fat deposition, serum hormones and inflammation-related gene expression in miniature pigs...

2020-11-16
Influence of Labrador Retriever\'s Behavior and Heart Rate Changes on the Success Rate of Guide Dog Training in Distance Test

Influence of Labrador Retriever's Behavior and Heart Rate Changes on the Success Rate of Guide Dog Training in Distance Test

Using distance test (DT) to evaluate the behavioral and heart rate characteristics of Labrador dogs, in order to provide effective behavioral methods and physiological basis for the preliminary screening of guide dogs...

2020-11-16
Inhibitory effect of low-frequency electroacupuncture on DRG P2X3 receptor in type 2 diabetic neuralgia rats

Inhibitory effect of low-frequency electroacupuncture on DRG P2X3 receptor in type 2 diabetic neuralgia rats

To observe the effect of low-frequency electroacupuncture (EA) on the pain threshold of type 2 diabetic neuropathic pain (DNP) model rats and the expression of P2X3 receptors in the L5 dorsal root ganglion (DRG)...

2020-11-16