内页大图
【Animal Modeling】-Preliminary study on knockout of MATP gene in mouse melanoma cell line using CRISPR-Cas9 system

【Animal Modeling】-Preliminary study on knockout of MATP gene in mouse melanoma cell line using CRISPR-Cas9 system

To use the CRISPR/Cas9 system to knock out the MATP gene in mouse melanoma cell lines, laying the foundation for the functional study of the MATP gene...

2022-06-07
【Animal Modeling】-Verification of the B2m gene silencing site in marmosets at the cellular level

【Animal Modeling】-Verification of the B2m gene silencing site in marmosets at the cellular level

To screen and verify the effective silencing target of marmoset B2m gene at the cellular level...

2022-06-07
【Animal modeling】-Optimization of SD rat skin chemical hair removal parameters based on D-optimal design

【Animal modeling】-Optimization of SD rat skin chemical hair removal parameters based on D-optimal design

To study the depilation parameters of SD rat skin, and to provide basic experimental conditions for establishing skin photoaging animal model...

2022-06-06
【Animal modeling】-Design and efficacy evaluation of anti-reflux device for positioning evaluation of orotracheal intubation in experimental rats

【Animal modeling】-Design and efficacy evaluation of anti-reflux device for positioning evaluation of orotracheal intubation in experimental rats

To improve the positioning technique of orotracheal intubation in experimental rats, improve the efficiency of endotracheal intubation and reduce complications...

2022-06-06
【Animal Modeling】-Effects of different samples and methods on the determination of blood biochemical indexes in rats

【Animal Modeling】-Effects of different samples and methods on the determination of blood biochemical indexes in rats

To compare the effects of two different samples of serum and plasma and different test methods on the measured values of blood biochemical indexes and blood glucose in rats...

2022-06-06
【Animal modeling】-The role and mechanism of miR-221 in H2O2-induced myocardial cell injury in rats

【Animal modeling】-The role and mechanism of miR-221 in H2O2-induced myocardial cell injury in rats

To investigate the role and mechanism of miR-221 in hydrogen peroxide (H2O2)-induced rat cardiomyocyte (H9c2) injury...

2022-06-06
【Animal Modeling】-Fluorescence two-dimensional electrophoresis to detect the differences in liver tissue proteomics between male and female mice

【Animal Modeling】-Fluorescence two-dimensional electrophoresis to detect the differences in liver tissue proteomics between male and female mice

To detect the differences in the expression of proteomes in the liver tissue of male and female mice, and to explore the mechanism of gender differences in the occurrence of liver diseases...

2022-06-06
【Animal Modeling】-Establishment and Application of In Vitro Culture System of Mouse Small Intestinal Organoids

【Animal Modeling】-Establishment and Application of In Vitro Culture System of Mouse Small Intestinal Organoids

To establish an in vitro model of intestinal epithelial cells—small intestinal organoid culture system, and to explore its related pathological detection techniques, so as to provide a convenient platform for the in vitro research of intestinal-relat...

2022-06-06
【Animal Modeling】-The mechanism of acute hyperglycemia affecting the first phase insulin secretion in mice

【Animal Modeling】-The mechanism of acute hyperglycemia affecting the first phase insulin secretion in mice

To observe the function and morphological changes of acute hyperglycemia affecting the first phase insulin secretion in mice...

2022-06-06
【Animal Modeling】- Abnormal glucose metabolism leads to changes in body weight in SIVmac239-infected northern flat-topped monkeys in acute phase

【Animal Modeling】- Abnormal glucose metabolism leads to changes in body weight in SIVmac239-infected northern flat-topped monkeys in acute phase

To investigate the effects of inflammatory factors, lipid metabolism and glucose metabolism on body weight in the acute phase of AIDS...

2022-06-06
【Animal modeling】-pathological comparative analysis of BALB/c mice infected with herpes simplex virus type Ⅱ through different routes

【Animal modeling】-pathological comparative analysis of BALB/c mice infected with herpes simplex virus type Ⅱ through different routes

To compare the pathological changes of BALB/c mice infected with herpes simplex virus type Ⅱ (HSV-2) by different routes...

2022-06-06
【Animal modeling】-The expression changes of dendritic cell surface factors in lung tissue of COPD rats and the intervention effect of CCL20 antibody

【Animal modeling】-The expression changes of dendritic cell surface factors in lung tissue of COPD rats and the intervention effect of CCL20 antibody

To understand the expression changes of dendritic cell surface factors OX62 and CD83 in the lungs of COPD rats, and to explore the intervention effect of CCL20 antibody...

2022-06-06
【Animal Modeling】-Effects of chronic corticosterone treatment on learning and memory and synapse-related proteins in mice

【Animal Modeling】-Effects of chronic corticosterone treatment on learning and memory and synapse-related proteins in mice

To establish a drinking method, chronically administer corticosterone, and observe the effects of corticosterone on learning and memory and synapse-related proteins...

2022-06-06
【Animal modeling】-Effect of rosuvastatin on myocardial matrix metalloproteins and inflammatory factors in rats with acute myocardial infarction

【Animal modeling】-Effect of rosuvastatin on myocardial matrix metalloproteins and inflammatory factors in rats with acute myocardial infarction

To observe the changes of matrix metalloproteinase MMPs, TIMP2 and inflammatory factors TNF-α and IL-1β in myocardial tissue of rats with acute myocardial infarction (AMI) treated with rosuvastatin...

2022-06-06
【Animal Modeling】-Effects of different frequencies of music on spatial learning and memory in mice

【Animal Modeling】-Effects of different frequencies of music on spatial learning and memory in mice

To preliminarily explore whether music affects the learning and memory ability of adult mice...

2022-06-06
【Animal Modeling】-Pathological Observation of Spontaneous Tumors in Aged SD Rats

【Animal Modeling】-Pathological Observation of Spontaneous Tumors in Aged SD Rats

To observe the occurrence of spontaneous tumors in SD rats, and to provide background data for the carcinogenicity test of new drugs...

2022-06-05