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【Animal Modeling】-Anterior cingulate cortex mechanism of electroacupuncture at different time interventions on anxiety behavior in pain aversion rats

【Animal Modeling】-Anterior cingulate cortex mechanism of electroacupuncture at different time interventions on anxiety behavior in pain aversion rats

To investigate the relieving effect of electroacupuncture on anxiety behavior in pain-aversion rats and its effect on N-methyl-D-aspartate and γ-aminobutyric acid receptors in anterior cingulate cortex...

2022-05-31
【Animal modeling】-Effect of morroniside on the expression of TIMP in the cortex of ischemia-reperfusion rats

【Animal modeling】-Effect of morroniside on the expression of TIMP in the cortex of ischemia-reperfusion rats

To study the effect of morroniside on the expression of tissue inhibitor of metalloproteinases in the cortex of rats with ischemia-reperfusion for 7 days...

2022-05-31
【Animal Modeling】-Effects of heat exposure in the second trimester on the intrauterine development of rat offspring and the expression of HSP70, Bax and Bcl-2 in the placenta

【Animal Modeling】-Effects of heat exposure in the second trimester on the intrauterine development of rat offspring and the expression of HSP70, Bax and Bcl-2 in the placenta

To investigate the effect of heat exposure in the second trimester on the intrauterine growth and development of rat placenta and offspring...

2022-05-31
【Animal modeling】-Influence of RNA interference inhibition of Beclin1 gene on proliferation and apoptosis of naked mole rat fibroblasts

【Animal modeling】-Influence of RNA interference inhibition of Beclin1 gene on proliferation and apoptosis of naked mole rat fibroblasts

To inhibit the expression of autophagy-regulating gene Beclin 1 by RNA interference technology, and to detect the effect of Beclin 1 expression on the proliferation and apoptosis of naked mole rat skin fibroblasts and the expression of p53, BAX, Bcl2...

2022-05-31
【Animal modeling】-Establishment and application of immunocomb detection method for simian immunodeficiency virus antibody

【Animal modeling】-Establishment and application of immunocomb detection method for simian immunodeficiency virus antibody

To prepare the SIV30 protein of simian immunodeficiency virus (SIV) by genetic engineering technology as an antigen diagnostic reagent, and to establish an immunocomb method (IC) for the specific detection of anti-SIV antibody IgG in the serum of exp...

2022-05-31
【Animal modeling】-Effect of Astragalus on endoplasmic reticulum stress response in vascular remodeling in hypertensive rats

【Animal modeling】-Effect of Astragalus on endoplasmic reticulum stress response in vascular remodeling in hypertensive rats

To study the effect of Astragalus on endoplasmic reticulum stress response (ERS) in vascular remodeling in hypertensive rats, and to explore the molecular mechanism of its vascular protection...

2022-05-31
【Animal modeling】-The effect of DHEA on superovulation and oocyte quality in mice

【Animal modeling】-The effect of DHEA on superovulation and oocyte quality in mice

To study the effect of dehydroepiandrosterone (DHEA) on superovulation and oocyte quality in C57BL/6J female mice and its mechanism...

2022-05-31
【Animal Model】-Effect of β-arrestin2 gene knockout on the function of mouse peritoneal macrophages

【Animal Model】-Effect of β-arrestin2 gene knockout on the function of mouse peritoneal macrophages

To investigate the effect of β-arrestin2 gene knockout on the function of mouse peritoneal macrophages...

2022-05-31
【Animal Modeling】-Exploring the neuroprotective effect of DAHP on brain trauma rats based on NOS pathway

【Animal Modeling】-Exploring the neuroprotective effect of DAHP on brain trauma rats based on NOS pathway

To investigate the neuroprotective effect of 2,4-diamine-6-hydroxypyrimidine (DAHP) on traumatic brain injury rats, and to explore its possible mechanism...

2022-05-31
【Animal Modeling】-Mechanism of Aspirin on the Control of Salt-Sensitive Hypertension in Rats

【Animal Modeling】-Mechanism of Aspirin on the Control of Salt-Sensitive Hypertension in Rats

To investigate the regulatory effect and related mechanism of aspirin on salt-sensitive hypertension in rats...

2022-05-31
【Animal modeling】-Distribution of adenovirus type 5 in C57BL/6J mice after infection by different routes

【Animal modeling】-Distribution of adenovirus type 5 in C57BL/6J mice after infection by different routes

To detect the distribution of adenovirus type 5 (Ad5) in C57BL6J after infection by four ways...

2022-05-31
【Animal Modeling】-Lactobacillus rhamnosus culture supernatant prevents Escherichia coli meningitis by inhibiting NF-κB pathway

【Animal Modeling】-Lactobacillus rhamnosus culture supernatant prevents Escherichia coli meningitis by inhibiting NF-κB pathway

To investigate whether Lactobacillus rhamnosus supernatant (LGG-CM) can block bacterial meningitis caused by E. coli K1 strain by inhibiting NF-κB pathway in vitro...

2022-05-31
【Animal modeling】-Effect of low selenium diet on the expressions of CD163, CD206 and CCR7 in the liver and kidney of rats

【Animal modeling】-Effect of low selenium diet on the expressions of CD163, CD206 and CCR7 in the liver and kidney of rats

To investigate the effect of low selenium diet on liver and kidney in rats, and the role of macrophage polarization to M1 and M2 in liver and kidney fibrosis...

2022-05-31
【Animal modeling】-Observation of the anesthesia effect of compound anesthesia on Wuzhishan miniature pigs for up to 8 hours

【Animal modeling】-Observation of the anesthesia effect of compound anesthesia on Wuzhishan miniature pigs for up to 8 hours

To observe the general anesthesia effect of ketamine?Sumianxin II and midazolam mixture for induction of anesthesia, and ketamine and propofol to maintain anesthesia on Wuzhishan miniature pigs for up to 8 hours?...

2022-05-31
【Animal Modeling】-Effect of Trichinella spiralis and its worm-derived protein on cecal ligation and puncture-induced sepsis in mice

【Animal Modeling】-Effect of Trichinella spiralis and its worm-derived protein on cecal ligation and puncture-induced sepsis in mice

To observe the effect of Trichinella spiralis and its parasite-derived protein on cecal ligation and puncture (CLP)-induced sepsis in mice...

2022-05-31
【Animal Modeling】-Comparative Analysis of Skin Wound Healing in BALB/c Mutant Curly-haired Mice

【Animal Modeling】-Comparative Analysis of Skin Wound Healing in BALB/c Mutant Curly-haired Mice

To investigate the differences between BALB/c mutant curly hair mice and control BALB/c mice in the natural healing process of skin injury...

2022-05-31