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【Animal Modeling】-Evaluation of the Operational Effect of Animal Nasal Aerosol Exposure Device

【Animal Modeling】-Evaluation of the Operational Effect of Animal Nasal Aerosol Exposure Device

The purpose of this study is to investigate whether the animal nasal aerosol exposure device can operate normally and generate aerosol particles with a specific particle size, and to explore the air tightness, distribution uniformity and disinfection...

2022-05-26
【Animal modeling】-Analysis of the genetic structure of microsatellites in three outbred guinea pigs

【Animal modeling】-Analysis of the genetic structure of microsatellites in three outbred guinea pigs

To evaluate the microsatellite genetic structure of the three outbred guinea pig populations cultivated in our school, and to screen the microsatellite loci showing differential alleles among different populations, so as to provide data for the futur...

2022-05-26
【Animal Modeling】-A comparative study of in situ liver cancer dynamic imaging and pathology in nude mice

【Animal Modeling】-A comparative study of in situ liver cancer dynamic imaging and pathology in nude mice

To dynamically monitor tumor growth in nude mice after orthotopic liver cancer modeling and to compare it with pathology, so as to determine the appropriate period of intervention therapy...

2022-05-26
【Animal Modeling】-Study finds first evidence of rapid changes in primate fur pigmentation

【Animal Modeling】-Study finds first evidence of rapid changes in primate fur pigmentation

Chameleons and squid can change their colors, but monkeys can\'t—until humans step in. Researchers found that a normally black long-haired howler monkey in Costa Rica began to develop distinctive yellow patches on its tail and legs...

2022-05-26
【Animal Modeling】-Analysis of fecal microbial diversity of wild tree shrews using Illumina MiSeq sequencing platform

【Animal Modeling】-Analysis of fecal microbial diversity of wild tree shrews using Illumina MiSeq sequencing platform

To analyze the structure and composition of the fecal flora of wild tree shrew by high-throughput sequencing technology, and to lay a foundation for the further development and utilization of this new experimental animal...

2022-05-26
【Animal modeling】-Experimental study on growth and reproduction of Tlr4 knockout mice

【Animal modeling】-Experimental study on growth and reproduction of Tlr4 knockout mice

To study the similarities and differences in growth and reproduction between Tlr4 knockout mice and KM mice...

2022-05-26
【Animal Modeling】-Comparison of Two Staining Methods for Rat Vaginal Smears

【Animal Modeling】-Comparison of Two Staining Methods for Rat Vaginal Smears

To find a simple staining method for determining the four stages of the rat estrous cycle by staining the vaginal smears of SD female rats to observe the cell morphology...

2022-05-26
【Animal modeling】-Establishment and identification of vitamin D receptor gene knockout mouse strain

【Animal modeling】-Establishment and identification of vitamin D receptor gene knockout mouse strain

To explore the optimal breeding method and identification method of vitamin D receptor (VDR) knockout mice, and to provide animal models for further study of VDR function and related diseases...

2022-05-26
【Animal Modeling】-Discussion on the Sequence Scheme of Reducing Image Respiration and Heartbeat Artifacts in In vivo Thoracic Scanning of Rats

【Animal Modeling】-Discussion on the Sequence Scheme of Reducing Image Respiration and Heartbeat Artifacts in In vivo Thoracic Scanning of Rats

To develop a sequence that reduces image breathing and heartbeat artifacts in 256-slice spiral CT rat in vivo chest CT scans...

2022-05-26
【Animal Modeling】-Effect of nicotine on changes of pain threshold plasticity and cardioprotection in rats with myocardial infarction

【Animal Modeling】-Effect of nicotine on changes of pain threshold plasticity and cardioprotection in rats with myocardial infarction

To observe the plastic changes of pain threshold in rats with myocardial infarction, and to explore the effect of nicotine on visceral pain and whether it has a protective effect on ischemic myocardium...

2022-05-26
[Animal Modeling]-Blocking the PD1/PD-L1 pathway mediated by macrophages inhibits the recurrence of tuberculosis in mice

[Animal Modeling]-Blocking the PD1/PD-L1 pathway mediated by macrophages inhibits the recurrence of tuberculosis in mice

Functional PD? Using L1 (programmed cell death ligand 1, PD 2 L1) monoclonal antibody, PD1/PD 3. To study the mechanism of immune intervention and relapse after tuberculosis treatment by blocking the L1 pathway...

2022-05-26
【Animal Modeling】-Effect of psycho-dependent heroin on embryonic development and Bax expression in brain tissue of rats

【Animal Modeling】-Effect of psycho-dependent heroin on embryonic development and Bax expression in brain tissue of rats

To investigate the effect of heroin, a psychotropic substance, on the development of embryonic rats and the expression of Bax in the brain...

2022-05-26
【Animal Modeling】-Effect of a single intraosseous injection of low-dose simvastatin on angiogenesis after myocardial infarction in rats

【Animal Modeling】-Effect of a single intraosseous injection of low-dose simvastatin on angiogenesis after myocardial infarction in rats

To study the effect of intraosseous local single injection of low-dose simvastatin on angiogenesis and cardiac function in rats after myocardial infarction...

2022-05-26
【Animal Modeling】-Effects of IL-27 and its receptors on the proliferation and transformation of lung fibroblasts

【Animal Modeling】-Effects of IL-27 and its receptors on the proliferation and transformation of lung fibroblasts

To investigate the effects of IL-27 and its receptor (WSX-1) on the proliferation, transformation and collagen synthesis of mouse lung fibroblasts induced by TGF-β1...

2022-05-26
【Animal Modeling】-Minocycline inhibits the hyperpolarization-activated current of glial neurons in the dorsal horn of rat spinal cord

【Animal Modeling】-Minocycline inhibits the hyperpolarization-activated current of glial neurons in the dorsal horn of rat spinal cord

To study the effect of minocycline on the hyperpolarization-activated current (Ih) of colloidal (SG) neurons in the spinal dorsal horn of rats...

2022-05-26
【Animal Modeling】-Experimental study of CD45 mAb-mediated 188Re-avidin two-step pretargeting targeting lymphoma

【Animal Modeling】-Experimental study of CD45 mAb-mediated 188Re-avidin two-step pretargeting targeting lymphoma

To establish a CD45 mAb-mediated two-step pre-localization method for 188Re-avidin, observe its biological distribution in tumor-bearing mice, and evaluate its feasibility in the treatment of lymphoma...

2022-05-26