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【Animal Modeling】-Screening and application of single nucleotide polymorphism markers for identification of four commonly used strains of rats

【Animal Modeling】-Screening and application of single nucleotide polymorphism markers for identification of four commonly used strains of rats

To screen out the single nucleotide polymorphisms that can rapidly identify four commonly used rat strains [Wistar rat, Goto-Kakizaki (GK) rat, Brown-Norway (BN) rat, Sprague-Dawley rat] sex, site and verify its reliability...

2022-05-25
【Animal Modeling】-Using a New Ultrasound Diagnostic Apparatus to Detect Cardiac Function in Rats

【Animal Modeling】-Using a New Ultrasound Diagnostic Apparatus to Detect Cardiac Function in Rats

To evaluate the cardiac function of rats by two-dimensional and M-mode echocardiography using a new type of ultrasonic diagnostic apparatus, and to understand the feasibility and accuracy of this method...

2022-05-25
【Animal modeling】-Experimental study on growth and reproduction of Tlr4 knockout mice

【Animal modeling】-Experimental study on growth and reproduction of Tlr4 knockout mice

To study the similarities and differences in growth and reproduction between Tlr4 knockout mice and KM mice...

2022-05-25
【Animal modeling】-Establishment and identification of vitamin D receptor gene knockout mouse strain

【Animal modeling】-Establishment and identification of vitamin D receptor gene knockout mouse strain

To explore the optimal breeding method and identification method of vitamin D receptor (VDR) knockout mice, and to provide animal models for further study of VDR function and related diseases...

2022-05-25
【Animal modeling】-Experimental study on puerarin alleviating radiation-induced acute intestinal mucosal injury in rats

【Animal modeling】-Experimental study on puerarin alleviating radiation-induced acute intestinal mucosal injury in rats

To study the protective effect of puerarin on the intestinal mucosal injury of SD rats induced by radiation and its molecular mechanism...

2022-05-19
【Animal Modeling】-Analysis of the expression levels of Rxra in six tissues of spontaneously diabetic gerbils

【Animal Modeling】-Analysis of the expression levels of Rxra in six tissues of spontaneously diabetic gerbils

To analyze the expression levels of Rxra gene in 6 tissues of diabetic gerbils, in order to explore the molecular mechanism of diabetes in gerbils...

2022-05-19
【Animal Modeling】-Preliminary study on the mechanism of hypoxic preconditioning reducing the susceptibility to epilepsy and its brain protective effect in rats

【Animal Modeling】-Preliminary study on the mechanism of hypoxic preconditioning reducing the susceptibility to epilepsy and its brain protective effect in rats

To preliminarily investigate the effect of intermittent hypoxic preconditioning on epileptic seizures in rats induced by lithium chloride and pilocarpine and its brain protective mechanism...

2022-05-19
【Animal modeling】-Protective effect of curcumin on renal fibrosis in 5/6 kidney ligation-induced chronic kidney disease mouse model

【Animal modeling】-Protective effect of curcumin on renal fibrosis in 5/6 kidney ligation-induced chronic kidney disease mouse model

To study the protective effect of curcumin on renal fibrosis in chronic kidney disease, and to explore the possible mechanism of action...

2022-05-19
[Animal Modeling]-Pathological Analysis of Spontaneous Giant Tumors in Rats

[Animal Modeling]-Pathological Analysis of Spontaneous Giant Tumors in Rats

To study the pathological characteristics of giant spontaneous tumors in Wistar and GK rats...

2022-05-19
【Animal modeling】-induced rheumatoid arthritis

【Animal modeling】-induced rheumatoid arthritis

So far, induced animal models have been the most widely used in RA research. Not only can you make rodents, but you can also make rabbits, dogs, and monkeys. There are many types of inducers, including AA, CIA and OIA models...

2022-05-19
【Animal Modeling】-Effect of plantar shock stress duration on anxiety-like behavior in rats

【Animal Modeling】-Effect of plantar shock stress duration on anxiety-like behavior in rats

To observe the effects of plantar shock stress duration on the elevated plus maze and anxiety-like behaviors in the opening test in rats...

2022-05-19
【Animal modeling】-Microsatellite DNA analysis of the genetic status of 24 domestic inbred strains of mice

【Animal modeling】-Microsatellite DNA analysis of the genetic status of 24 domestic inbred strains of mice

To analyze the genetic status of 24 domestic inbred mice using microsatellite loci...

2022-05-19
【Animal modeling】-Changes of IL-6, SOD and MDA in the lung tissue of rats with acute pulmonary edema

【Animal modeling】-Changes of IL-6, SOD and MDA in the lung tissue of rats with acute pulmonary edema

To investigate the changes and significance of malondialdehyde, superoxide dismutase and interleukin-6 in lung tissue of acute hypoxia-induced acute pulmonary edema in rats...

2022-05-19
【Animal modeling】-Effect of PLCζ on oocyte fertilization and embryonic development after injection of mouse round spermatids

【Animal modeling】-Effect of PLCζ on oocyte fertilization and embryonic development after injection of mouse round spermatids

To investigate the feasibility of PLCζ as an activator and its effect on oocyte fertilization and embryonic development after ROSI...

2022-05-19
【Animal Modeling】-Discussion on the Sequence Scheme of Reducing Image Respiration and Heartbeat Artifacts in In vivo Thoracic Scanning of Rats

【Animal Modeling】-Discussion on the Sequence Scheme of Reducing Image Respiration and Heartbeat Artifacts in In vivo Thoracic Scanning of Rats

To develop a sequence that reduces image breathing and heartbeat artifacts in 256-slice spiral CT rat in vivo chest CT scans...

2022-05-19
【Animal Modeling】-Exploration on the Application of Automatic Control Technology System of Laboratory Animal Barrier Facility System

【Animal Modeling】-Exploration on the Application of Automatic Control Technology System of Laboratory Animal Barrier Facility System

To realize the stable operation of the experimental animal barrier system, research and explore the automatic control technology of the experimental animal barrier system...

2022-05-19