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【Animal modeling】-Optimization of dose-response relationship between N-ethyl-N-nitrosourea and cyclophosphamide in pig-a gene mutation test in rats

【Animal modeling】-Optimization of dose-response relationship between N-ethyl-N-nitrosourea and cyclophosphamide in pig-a gene mutation test in rats

To study the effect of different doses of N-ethyl-N-nitrosourea (ENU) and cyclophosphamide (CP) on the deletion rate of ankyrin CD59 on the peripheral blood red blood cell surface of SD rats, and to optimize the Pig-a gene mutation test Detection met...

2022-05-17
【Animal modeling】-Combined with high-resolution MRI and micro-CT to evaluate the repairing effect of Taohong Siwu Decoction on femoral head necrosis in rabbits

【Animal modeling】-Combined with high-resolution MRI and micro-CT to evaluate the repairing effect of Taohong Siwu Decoction on femoral head necrosis in rabbits

To establish a rabbit model of steroid-induced necrosis of the femoral head, and to evaluate the repairing effect of Taohong Siwu Decoction (THSWD) on the microscopic bone structure damage of SIONFH combined with high-resolution MRI and micro-CT...

2022-05-17
【Animal Modeling】-Effects of intraperitoneal injection of human tumor cells into fetal mice in pregnant mice on the growth and development of fetal mice

【Animal Modeling】-Effects of intraperitoneal injection of human tumor cells into fetal mice in pregnant mice on the growth and development of fetal mice

To investigate the effect of intraperitoneal injection of human tumor HepG2 cells on fetal mouse growth and development in pregnant mice...

2022-05-17
【Animal Modeling】-The effect of icariin on experimental IgA nephropathy in rats and related mechanisms

【Animal Modeling】-The effect of icariin on experimental IgA nephropathy in rats and related mechanisms

To explore the effects of different doses of icariin on rats with experimental IgA nephropathy, and to study its related mechanism...

2022-05-17
【Animal Modeling】-CBA/CaJ Mice Organ Weight, Blood Physiological and Biochemical Indexes and Immune Cell Proportion

【Animal Modeling】-CBA/CaJ Mice Organ Weight, Blood Physiological and Biochemical Indexes and Immune Cell Proportion

To determine the basic biological indicators of SPF CBA/CaJ mice, and to lay a foundation for better use of this strain of mice for biomedical research...

2022-05-16
【Animal modeling】-Polymorphism analysis of PPARγ2 gene promoter in Wuzhishan miniature pigs

【Animal modeling】-Polymorphism analysis of PPARγ2 gene promoter in Wuzhishan miniature pigs

To analyze the polymorphisms in the regulatory region of the PPARγ2 gene promoter in Wuzhishan miniature pigs...

2022-05-16
【Animal Modeling】-Analysis of Bacterial Community Diversity in Large Intestine Contents of Tree Shrews

【Animal Modeling】-Analysis of Bacterial Community Diversity in Large Intestine Contents of Tree Shrews

To analyze the structure and composition of E. coli bacteria in tree shrew by high-throughput sequencing technology...

2022-05-16
【Animal Modeling】-improved New Zealand Rabbit Common Carotid Artery Cannulation Fixation Method

【Animal Modeling】-improved New Zealand Rabbit Common Carotid Artery Cannulation Fixation Method

To investigate a stable, not easy to fall off, and continuous and timed blood collection method for the common carotid artery cannulation of New Zealand rabbits...

2022-05-16
【Animal Modeling】-Evaluation of the Operational Effect of Animal Nasal Aerosol Exposure Device

【Animal Modeling】-Evaluation of the Operational Effect of Animal Nasal Aerosol Exposure Device

The purpose of this study is to investigate whether the animal nasal aerosol exposure device can operate normally and generate aerosol particles with a specific particle size, and to explore the air tightness, distribution uniformity and disinfection...

2022-05-16
【Animal Modeling】-Screening and application of single nucleotide polymorphism markers for identification of four commonly used strains of rats

【Animal Modeling】-Screening and application of single nucleotide polymorphism markers for identification of four commonly used strains of rats

To screen out the single nucleosides that can rapidly identify four commonly used rat strains [Wistar rat, Goto-Kakizaki (GK) rat, Brown-Norway (BN) rat, Sprague-Dawley (SD) rat] acid polymorphism sites and verify their reliability...

2022-05-16
【Animal Modeling】-Using a New Ultrasound Diagnostic Apparatus to Detect Cardiac Function in Rats

【Animal Modeling】-Using a New Ultrasound Diagnostic Apparatus to Detect Cardiac Function in Rats

To evaluate the cardiac function of rats by two-dimensional and M-mode echocardiography using a new type of ultrasonic diagnostic apparatus, and to understand the feasibility and accuracy of this method...

2022-05-16
【Animal Modeling】-Study found a new mechanism of competition among different iron transport pathways in Drosophila melanogaster

【Animal Modeling】-Study found a new mechanism of competition among different iron transport pathways in Drosophila melanogaster

Xiao Guiran, a professor at the School of Food and Bioengineering, Hefei University of Technology, led a team to discover that Drosophila melanogaster transferrin1 (transferrin1) is involved in iron transport in vivo and competes with ferritin...

2022-05-16
【Animal modeling】-Effect of PLCζ on oocyte fertilization and embryonic development after injection of mouse round spermatids

【Animal modeling】-Effect of PLCζ on oocyte fertilization and embryonic development after injection of mouse round spermatids

To investigate the feasibility of PLCζ as an activator and its effect on oocyte fertilization and embryonic development after ROSI...

2022-05-16
【Animal Modeling】-Exploration on the Application of Automatic Control Technology System of Laboratory Animal Barrier Facility System

【Animal Modeling】-Exploration on the Application of Automatic Control Technology System of Laboratory Animal Barrier Facility System

To realize the stable operation of the experimental animal barrier system, research and explore the automatic control technology of the experimental animal barrier system...

2022-05-16
【Animal modeling】-The expression changes and effects of BDNF and its receptor TrkB in hypoxia-preconditioned mice

【Animal modeling】-The expression changes and effects of BDNF and its receptor TrkB in hypoxia-preconditioned mice

To explore the expression changes and effects of BDNF, TrkB receptor and BDNF/TrkB signaling pathway in acute hypoxia and hypoxia preconditioning mice, to further improve the molecular mechanism of hypoxia preconditioning neuroprotection, and to prov...

2022-05-16
【Animal Modeling】-Measurement and Significance of Noninvasive Pulmonary Function in Mice

【Animal Modeling】-Measurement and Significance of Noninvasive Pulmonary Function in Mice

To detect non-invasive pulmonary function indexes in C57BL/6 mice, and to provide a basis for the monitoring of pulmonary function in experimental studies in mice...

2022-05-16