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【Animal Modeling】-The effect of rapid modeling of KK mouse diet on related indicators of KK/Upj-Ay/J mice

【Animal Modeling】-The effect of rapid modeling of KK mouse diet on related indicators of KK/Upj-Ay/J mice

To study the rapid modeling of KK mouse diet and its effect on related indexes in KK/Upj-Ay/J mice...

2022-06-27
【Animal modeling】-Effect of lamotrigine on the expression of PGP, MVP and amino acid content in the hippocampus of chronic epilepsy rats

【Animal modeling】-Effect of lamotrigine on the expression of PGP, MVP and amino acid content in the hippocampus of chronic epilepsy rats

To investigate the effect of lamotrigine on the expression and amino acid content of P-glycoprotein and main vault protein in the hippocampus of chronic epilepsy rats...

2022-06-27
【Animal Modeling】-Protein Transformation Regulation Mechanism of Rat Skeletal Muscle Atrophy Induced by Hypoxia Exposure

【Animal Modeling】-Protein Transformation Regulation Mechanism of Rat Skeletal Muscle Atrophy Induced by Hypoxia Exposure

To compare the expression of genes related to protein synthesis and decomposition in skeletal muscle of rats under hypoxia exposure and normoxia paired with hypoxic feeding intervention (semi-starvation state), in order to explore the possible mechan...

2022-06-27
【Animal Modeling】-Effect of fasting time on glucose tolerance and insulin secretion in Kunming mice

【Animal Modeling】-Effect of fasting time on glucose tolerance and insulin secretion in Kunming mice

In order to explore the stable, reliable and reasonable fasting time of OGTT in Kunming mice, which are used the most in China in a specific environment...

2022-06-27
【Animal Modeling】-Human umbilical cord mesenchymal stem cell transplantation repairs premature ovarian failure in rats

【Animal Modeling】-Human umbilical cord mesenchymal stem cell transplantation repairs premature ovarian failure in rats

To investigate the mechanism of transplantation of human umbilical cord mesenchymal stem cells (hUCMSCs) to restore ovarian function in rats with premature ovarian failure...

2022-06-27
【Animal modeling】-Effect of selenium-enriched rice bran instead of organic selenium on growth performance and antioxidant function of experimental young rabbits

【Animal modeling】-Effect of selenium-enriched rice bran instead of organic selenium on growth performance and antioxidant function of experimental young rabbits

To study the effect of selenium-enriched rice bran instead of organic selenium supplementation on the growth performance and antioxidant function of young rabbits...

2022-06-27
【Animal modeling】-Effect of Shenren Huoxue Granules on TGF-β1/Smad signaling pathway in carbon tetrachloride-induced hepatic fibrosis in rats

【Animal modeling】-Effect of Shenren Huoxue Granules on TGF-β1/Smad signaling pathway in carbon tetrachloride-induced hepatic fibrosis in rats

To observe the effect of Shenren Huoxue Granules on the TGF-β1/Smad signaling pathway of carbon tetrachloride-induced liver fibrosis in rats, and to explore the mechanism of Shenren Huoxue Granules in the treatment of liver fibrosis...

2022-06-27
【Animal Modeling】-Effect of quinsulfacyclohexanone on diabetic nephropathy in rats and its effect on the expression of AngⅡ and VEGF in the kidney

【Animal Modeling】-Effect of quinsulfacyclohexanone on diabetic nephropathy in rats and its effect on the expression of AngⅡ and VEGF in the kidney

To study the effect of quinsulfacyclohexanone on diabetic nephropathy in rats and its effects on the expression of angiotensin Ⅱ and vascular endothelial growth factor in the kidneys...

2022-06-27
【Animal modeling】- Guanxinning tablet inhibits myocardial cell apoptosis in chronic heart failure mice through PI3K/AKT signaling pathway

【Animal modeling】- Guanxinning tablet inhibits myocardial cell apoptosis in chronic heart failure mice through PI3K/AKT signaling pathway

To observe the therapeutic effect of Guanxinning Tablets on chronic heart failure (CHF) mice, and to explore its action pathway from myocardial cell apoptosis and related cell signaling pathways, so as to provide experimental basis for the clinical a...

2022-06-27
【Animal modeling】-Effect of natural enemy sound stress on anxiety-like behavior in SD rats

【Animal modeling】-Effect of natural enemy sound stress on anxiety-like behavior in SD rats

To observe the effects of natural enemy sounds on anxiety-like behaviors of SD rats under different durations and repeated stress...

2022-06-24
【Animal Modeling】-Injury and mechanism of short-term PM2.5 exposure to uterine tissue in rats

【Animal Modeling】-Injury and mechanism of short-term PM2.5 exposure to uterine tissue in rats

To study the damage effect and possible molecular mechanism of PM2...

2022-06-24
【Animal modeling】-Anti-atherosclerosis and cardioprotective effects of perilla seed extract in ApoE-/- mice

【Animal modeling】-Anti-atherosclerosis and cardioprotective effects of perilla seed extract in ApoE-/- mice

To study the effect and molecular mechanism of perilla seed oily extract (PSO) on reducing plaque formation and cardioprotection in ApoE-/- mice...

2022-06-24
【Animal Modeling】-Comparison of intravenous injection needle and self-made PE-50 needle in the measurement of intracavernous pressure in rats

【Animal Modeling】-Comparison of intravenous injection needle and self-made PE-50 needle in the measurement of intracavernous pressure in rats

To investigate the method of electrical stimulation of the cavernosal nerve of the penis to detect the intracavernous pressure, and to compare the differences between the two materials (PE-50 tube needle and intravenous infusion needle) for detecting...

2022-06-24
【Animal modeling】-Protective effect of aerobic exercise combined with paeonol PLGA nanoparticles on obese rats with hyperlipidemia

【Animal modeling】-Protective effect of aerobic exercise combined with paeonol PLGA nanoparticles on obese rats with hyperlipidemia

To investigate the effect of aerobic exercise combined with paeonol PLGA nanoparticles on blood biochemistry and lipid metabolism in obese rats with hyperlipidemia...

2022-06-24
【Animal modeling】-Effect of busulfan on peripheral blood cells and bone marrow cells of type 2 diabetic KKAy mice

【Animal modeling】-Effect of busulfan on peripheral blood cells and bone marrow cells of type 2 diabetic KKAy mice

To observe the damage effect of busulfan on the function of hematopoietic system in KK/upj-Ay/J mice of type 2 diabetes mellitus and compare it with the control C57BL/6J(B6) mice...

2022-06-24
【Animal Model】-Effects of nicotine on changes in pain threshold plasticity and cardioprotection in rats with myocardial infarction

【Animal Model】-Effects of nicotine on changes in pain threshold plasticity and cardioprotection in rats with myocardial infarction

To observe the plastic changes of pain threshold in rats with myocardial infarction, and to explore the effect of nicotine on visceral pain and whether it has a protective effect on ischemic myocardium...

2022-06-24