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【Animal Modeling】-Analysis of the effect of microflora-sensing AHLs molecules on the diversity of intestinal microflora in mice

【Animal Modeling】-Analysis of the effect of microflora-sensing AHLs molecules on the diversity of intestinal microflora in mice

To investigate the effect of the microflora-sensing signal molecule N-acylhomoserine lactone on the composition of intestinal microflora in mice, so as to provide theoretical basis for the disturbance of intestinal microecology under infection...

2022-06-23
【Animal modeling】-Preliminary study on the toxicity of different extracts of Psoraleae on rats

【Animal modeling】-Preliminary study on the toxicity of different extracts of Psoraleae on rats

To study the toxicity of oral administration of different extracts of Psoralea in rats, and to provide a safe basis for its clinical application...

2022-06-23
【Animal Modeling】-Effect of Western Diet on Apolipoprotein E Knockout Mice

【Animal Modeling】-Effect of Western Diet on Apolipoprotein E Knockout Mice

To study the effect of western diet and standard diet on hematology and pathology of apolipoprotein E knockout mice (ApoE-/-)...

2022-06-23
【Animal Modeling】-Study on the inflammatory response of staphylococcus aureus infected by deep second degree scald in sterile rats

【Animal Modeling】-Study on the inflammatory response of staphylococcus aureus infected by deep second degree scald in sterile rats

To explore the inflammatory response of sterile rats after deep second-degree scald wounds were infected with Staphylococcus aureus, the test used sterile rats and SPF rats to establish deep second-degree scald models and post-scald Staphylococcus au...

2022-06-23
【Animal Modeling】-Effects of Unpredictable Stress Stimulation on the Immunity and Microflora of the Gastrointestinal Tract in Rats

【Animal Modeling】-Effects of Unpredictable Stress Stimulation on the Immunity and Microflora of the Gastrointestinal Tract in Rats

To analyze the effects of unpredictable stress on the gastrointestinal immune system and microbial population by observing the rats after 9 days of unpredictable stress stimulation, so as to provide a reference for the study of chronic stress on gast...

2022-06-23
【Animal Modeling】-Effect of Naoshuantong Capsule on blood lipid levels in atherosclerotic mice

【Animal Modeling】-Effect of Naoshuantong Capsule on blood lipid levels in atherosclerotic mice

To observe the effect of Naoshuantong Capsules on blood lipid levels in atherosclerotic mice, and to explore the mechanism of Naoshuantong Capsules in the treatment of stroke...

2022-06-23
【Animal Modeling】-Study on the effect of puffing on the nutritional components of experimental dog food

【Animal Modeling】-Study on the effect of puffing on the nutritional components of experimental dog food

Dogs are one of the earliest domesticated animals by humans. In the 1940s, dogs began to be used as experimental animals for research. In biomedicine, they were mainly used in experimental surgery, basic medicine, pharmacology, toxicology and some di...

2022-06-23
【Animal Modeling】-Correlation of BDNF and VEGF expression in hippocampus and forebrain cortex and chronic stress-induced depression in mice

【Animal Modeling】-Correlation of BDNF and VEGF expression in hippocampus and forebrain cortex and chronic stress-induced depression in mice

To investigate the correlation between the expression of brain-derived neurotrophic factor (BDNF) and vascular endothelial growth factor (VEGF) in hippocampus and forebrain cortex and chronic stress-induced depression in mice...

2022-06-23
【Animal Modeling】-Comparative study on the evaluation of left ventricular function by micro-CT, ultrasound and aortic cannulation in small animals

【Animal Modeling】-Comparative study on the evaluation of left ventricular function by micro-CT, ultrasound and aortic cannulation in small animals

To study the consistency and correlation of left ventricular function parameters measured by micro-CT, aortic cannulation and echocardiography, and to evaluate the scientific application value of micro-CT in evaluating left ventricular function...

2022-06-23
【Animal Modeling】-Isoproterenol-induced myocardial ischemia-induced changes in the pathological tissue of myocardial cells

【Animal Modeling】-Isoproterenol-induced myocardial ischemia-induced changes in the pathological tissue of myocardial cells

To observe the expression of HE staining, VEGF (vascular endothelial growth factor) and FCF (fibroblast growth factor) in myocardial tissue sections induced by subcutaneous injection of isoproterenol (1 mg/kg body weight) for different days in rats w...

2022-06-23
【Animal modeling】-Study on the inhibitory effect of low molecular weight heparin on PICC-related thrombosis in experimental rabbits

【Animal modeling】-Study on the inhibitory effect of low molecular weight heparin on PICC-related thrombosis in experimental rabbits

To investigate the inhibitory effect of different concentrations of low molecular weight heparin on PICC-related thrombosis...

2022-06-23
【Animal modeling】-Inhibitory effect of ethyl acetate extract of Radix Radix officinalis on mouse hepatocellular carcinoma cells and orthotopic transplanted tumors

【Animal modeling】-Inhibitory effect of ethyl acetate extract of Radix Radix officinalis on mouse hepatocellular carcinoma cells and orthotopic transplanted tumors

To investigate the inhibitory effect of ethyl acetate extract of Saxifrage Radix on mouse hepatocellular carcinoma cells and orthotopic transplanted tumors...

2022-06-23
【Animal modeling】-Effect of curcumin on Keap1/ARE signaling pathway and bile acid enterohepatic circulation in liver cancer model mice

【Animal modeling】-Effect of curcumin on Keap1/ARE signaling pathway and bile acid enterohepatic circulation in liver cancer model mice

To investigate the effect of curcumin on cytoplasmic protein chaperone (Keap1)/antioxidant response element (ARE) signaling pathway and bile acid enterohepatic circulation in liver cancer model mice...

2022-06-23
【Animal modeling】-Effect of aloin on NOX4/ROS/p38 MAPK signaling pathway and podocyte function in diabetic nephropathy rats

【Animal modeling】-Effect of aloin on NOX4/ROS/p38 MAPK signaling pathway and podocyte function in diabetic nephropathy rats

To investigate the effects of aloin on podocyte function and nicotinamide adenine dinucleotide phosphate oxidase 4 (NOX4)/reactive oxygen species (ROS)/p38 mitogen-activated protein kinase (p38 MAPK) signaling in diabetic nephropathy (DN) rats pathwa...

2022-06-23
【Animal Modeling】-Study on the autophagy mechanism of Zhenwu Decoction on cardiomyocytes in rats with heart failure due to deficiency of heart and kidney yang

【Animal Modeling】-Study on the autophagy mechanism of Zhenwu Decoction on cardiomyocytes in rats with heart failure due to deficiency of heart and kidney yang

To study the protective autophagy mechanism of Zhenwu Decoction on cardiomyocytes in rats with heart and kidney yang deficiency...

2022-06-23
【Animal Modeling】-Application of intracavitary shunt plug in rat abdominal cavity heterotopic heart transplantation

【Animal Modeling】-Application of intracavitary shunt plug in rat abdominal cavity heterotopic heart transplantation

To investigate the application of intravascular shunt thrombus in establishing a rat model of heterotopic heart transplantation in the abdominal cavity...

2022-06-23