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【Animal Modeling】-Effect of hypoxia training on Ghrelin-GHSR pathway in obese mice

【Animal Modeling】-Effect of hypoxia training on Ghrelin-GHSR pathway in obese mice

To apply hypoxic training to obese mice and observe the changes of GHSR levels in gastric tissue and hypothalamus, so as to explore whether hypoxic training affects the Ghrelin-GHSR pathway to improve obesity...

2022-03-21
【Animal Modeling】-Study on the antitumor effect of Xiuzhen mushroom powder on H22 tumor-bearing mice in vivo

【Animal Modeling】-Study on the antitumor effect of Xiuzhen mushroom powder on H22 tumor-bearing mice in vivo

The purpose of this experiment was to study the anti-tumor effect of Xiuzhen Mushroom and its anti-tumor mechanism...

2022-03-21
【Animal modeling】-The effect of simulated aging rat astrocyte conditioned medium on the proliferation of neural stem cells

【Animal modeling】-The effect of simulated aging rat astrocyte conditioned medium on the proliferation of neural stem cells

To establish a rat astrocyte aging model, simulate the aging of astrocytes in aged rats, and explore the effect of aging astrocyte conditioned medium on the proliferation of neural stem cells...

2022-03-21
【Animal Modeling】-Effect and mechanism of acute liver injury in mice on brown adipose tissue function

【Animal Modeling】-Effect and mechanism of acute liver injury in mice on brown adipose tissue function

To investigate the effects of carbon tetrachloride (CC14 ) on brown adipose tissue in mice with acute liver injury at different time points and the related mechanisms...

2022-03-21
【Animal modeling】-Preparation of curcumin nanoemulsion and its protective effect on myocardial ischemia-reperfusion in rats

【Animal modeling】-Preparation of curcumin nanoemulsion and its protective effect on myocardial ischemia-reperfusion in rats

To construct curcumin (CUR) nanoemulsion drug delivery system and study its protective effect and mechanism on myocardial ischemia-reperfusion in rats...

2022-03-21
【Animal modeling】-Effect of taurine on growth axis hormones and genes in intrauterine growth restriction pregnant mice

【Animal modeling】-Effect of taurine on growth axis hormones and genes in intrauterine growth restriction pregnant mice

To observe the effect of taurine on the expression of blood hormones and IGF gene in intrauterine growth restriction pregnant mice...

2022-03-21
【Animal Modeling】-Deletion of MD1 increases the susceptibility to ventricular arrhythmia in obese mice by activating the TLR4/MyD88 signaling pathway

【Animal Modeling】-Deletion of MD1 increases the susceptibility to ventricular arrhythmia in obese mice by activating the TLR4/MyD88 signaling pathway

To investigate the deletion of myeloid differentiation protein 1 (MD1) increases the susceptibility of ventricular arrhythmia in obese mice by activating Toll-like receptor 4 (TLR4)/myeloid differentiation factor (MyD88) signaling pathway...

2022-03-21
【Animal Modeling】-Effects of intermedia and adrenomedullin on cerebral microcirculation in rats with focal cerebral ischemia

【Animal Modeling】-Effects of intermedia and adrenomedullin on cerebral microcirculation in rats with focal cerebral ischemia

To investigate the effects of intermedin and adrenomedullin on cerebral microcirculation in rats with focal cerebral ischemia...

2022-03-19
【Animal Modeling】-Developmental Toxicity of Intravenous Cyclophosphamide on New Zealand Rabbit Embryos and Fetuses

【Animal Modeling】-Developmental Toxicity of Intravenous Cyclophosphamide on New Zealand Rabbit Embryos and Fetuses

To give cyclophosphamide intravenously to pregnant rabbits to observe its toxicity and performance on embryos and fetuses of pregnant rabbits, and to provide reference for selecting cyclophosphamide as a positive control...

2022-03-19
【Animal Modeling】-Study on the effect of vepromide combined with fluoxetine hydrochloride on depressive mice

【Animal Modeling】-Study on the effect of vepromide combined with fluoxetine hydrochloride on depressive mice

To investigate the effect of Weipronamine capsules combined with fluoxetine hydrochloride capsules on depression in mice...

2022-03-19
【Animal Modeling】-Construction and identification of an immunohumanized mouse model of prostate cancer

【Animal Modeling】-Construction and identification of an immunohumanized mouse model of prostate cancer

To construct a mouse model of humanized immune system and transplant it into human prostate cancer cell lines, so as to be used for the research of prostate cancer immunotherapy drugs...

2022-03-19
【Animal Modeling】-Effect of Naoshuantong Capsule on blood lipid levels in atherosclerotic mice

【Animal Modeling】-Effect of Naoshuantong Capsule on blood lipid levels in atherosclerotic mice

To observe the effect of Naoshuantong Capsule on blood lipid levels in atherosclerotic mice, and to explore the mechanism of Naoshuantong Capsule in the treatment of stroke...

2022-03-19
【Animal Modeling】-Construction and identification of an immunohumanized mouse model of prostate cancer

【Animal Modeling】-Construction and identification of an immunohumanized mouse model of prostate cancer

To construct a mouse model of humanized immune system and transplant it into human prostate cancer cell lines, so as to be used for the research of prostate cancer immunotherapy drugs...

2022-03-18
【Animal Modeling】-Based on the Rho/Rho-kinase signaling pathway to investigate the effect of propofol on reducing cerebral ischemia-reperfusion injury in rats

【Animal Modeling】-Based on the Rho/Rho-kinase signaling pathway to investigate the effect of propofol on reducing cerebral ischemia-reperfusion injury in rats

To investigate the effect of propofol on reducing cerebral ischemia-reperfusion injury in rats based on Rho/Rho-kinase signaling pathway...

2022-03-18
【Animal Modeling】-The effect of human umbilical cord mesenchymal stem cells on the level of autophagy in the hippocampus of natural aging rats

【Animal Modeling】-The effect of human umbilical cord mesenchymal stem cells on the level of autophagy in the hippocampus of natural aging rats

To investigate whether transplantation of human umbilical cord mesenchymal stem cells can improve learning and memory and cognitive decline by regulating the level of autophagy in naturally aging rats...

2022-03-18
【Animal modeling】-The lipid-lowering effect of citrus polymethoxyflavonoid biscuits on hyperlipidemia mice

【Animal modeling】-The lipid-lowering effect of citrus polymethoxyflavonoid biscuits on hyperlipidemia mice

This study was the first to evaluate the lipid-lowering effect of adding citrus polymethoxyflavone powder to biscuits in a hyperlipidemia mouse model through the measurement of lipid metabolism experimental indicators, aiming to provide a new functio...

2022-03-18